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Tramadol, Love it or hate it

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drivinthattrain

drivinthattrain

Bluelighter
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Aug 26, 2012
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Hello, This is my first post since joining. I have been following,using, and learning from this site for a long time though. My "twin" wanted to shed some perspective about tramadol. He has been a heavy opiate user in the past, at his peak was 80mg oxycotin once a day and 30mg oxycodone four times a day. Eventually all good things come to an end an family became more important
. However, he still suffers from pain, and a strange attraction to euphoria ;) Tramadol seems to be a very picked on med by opiate lovers.
He is in the medical field and has a foundation with pharamcology and phamacuetics. My twin, after a few weeks of no pain pills can take 150mg of tramadol and feel like he just took 30mgs of hydro, very stimulating, decent euphoria, kick in 4 mgs of k-pins (He has a very high
benzo tolerance) and its wonderful. He has always found it fascinating how drugs can have completely opposite effects on people, brain chemistry is such a mystery to him. In promoting harm reduction, although over dramatized, tramadol does lower the seizure threshold, so people prone to seizures should aviod this dr
ug, he has taken very high doses and has never had a problem, he always has a decent level of klonopin built up in his sysytem as well, and that helps, its not a typical anti-siezure med but it is the best
anticonvulsant benzo, which he has used on the job to treat siezures. Another odd fact about him, is that not only does he covet euphoria and loves opiates, he does not like getting the nods....I know this will raise eyebrows. He enjoys the energy, euphoria. He also enjoys Stims, but they just dont stand up to a good opiate, for ma
ny reasons....re-dosing sucks, crashes suck, doesnt last long.....but 2 hours on 110mgs of Ritalin....daytrana patch chewed up is bliss...but, then all over and redosing just makes i
t worse. Opiates, he can sustain for a long long time. Keep in mind, Before daytrana he hated Ritalin and preferred Adderall any day...but daytrana is Magic...but thats off topic. Currently he is on 250mgs tramadol and 6mgs klonopin and feels that lovey dovey opiate high with a touch of energy
. He knows the chemistry behind tramadol, and how it acts on seratonin, and acts weakly on opiate receptors, but he puts it on par with hydro. He has had every opiate on the U.S market expect Heroin. Been on the iv drips and all that great stuff. Sorry for the long post. Are there any out there that love opiates, find tramadol euphoric and dont particularly like the nods? Probably not, He is a strange one....oh,
He is completely immune to placebo, too old, too many drugs and too skeptical. He will be posting more on drug synergy, combos and potentiation on other drugs of "fun". Peace. Although Im not sure there is a topic that hasnt been disscussed here. Such a wonderful site and resource.
 
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Man, make paragraphs; reading such wall of text is "unpleasant"

When I started with tramadol, I had very little opiate tolerance and experience (some codeine, but not too often). The first few times were magical. I was full of energy, talkative (that's not usual for me), and with doses ~~300mg euphoric and nodding. I never knew why so many people say it's worthless drug. It was this way for quite long time (due to lack of permanent source never for more than few days in row), until I got addicted to PST (poppy seed tea). Since then I wasn't taking too much pleasure from it.

Once I got a package of 30x100mg extended release (Retard) tabs, and only first day or two I found it nice. After that I didn't find it that good, even when I took 700 or 800mg.

Recently while WD from PST I got my hands on 150mg in ampules and IM-ed it along with 10mg of diazepam (PO) and I was relived form WD symptoms and felt really good.
It's quite unpredictable drug for me. Also friends who I know react to it differently. One felt anger, other not too much, one felt nice, but the next day she was very sick, and other two who felt similar to me.

As advice to OP, I'd say you should be aware of possibility of tramadol WD, which I haven't felt myself, but I've read that it's worse and longer than "normal" opiates
 
I have read that as well, I tend to take breaks to avoid. Sorry about the fragments and run-ons. My first post, and a little medicated.

Moderation is your premise, and a wise one.
 
I'm one of the rare ones, i actually love tramadol. To start with i found it like a typical opioid and right at the start i could find myself nodding at 150mg. As my opiate tolerance has grown over the years those effects from tramadol are long gone.
What it is to me now tho is a good anti depressant, and good pick me up. 200-300 mg keeps me happy, energetic, and it lasts all day. Bit too easy to use daily and withdrawal is hell.
I also found doses above 500mg (yeah i know 400is the seizure limit) can be very uncomfortable, nausea, sweating, really unpleasant headrushes.
But all in all if i stick to 200-300mg a day, tramadol works well for me. Im a noticably better person on it.
 
i used to love tramadol while i was still not too tolerant to it. would provide a great buzz and a general sense of warmth all around my body...

i don't dare to cross 400mg though, and i can't get high off 300mg anymore :(

would clonazepam reduce a risk of seizure from them?
 
if i were to take say 2mg of clonazepam could i take 800mg of tramadol?

i hate clonazepam - but if it meant that i could take more tramadol i'd happily take it up.
 
Nobody can tell you that for sure.
As I've written, I've taken 700 or 800mg without any anticonvulasnt (btw, I wonder if beer highers the seizure threshold), friend took 1g and I know from trip reports that we're not the only people with this "immunity".

400mg isn't a magic number, there's plot linking amounts of seizure attacks with dose of tramadol, and I believe pharmacists looked at the graph and said "400mg a day seems to be quite safe". I don't believe that the risk between, say, 350 and 450mg doubles, or even is 1,5 times higher.

That said, YOU DON'T WANT to have the attack and you don't know how much you'd have to take to have one.
With 2mg clons it seems not so dangerous, but I repeat - you never know for sure.
 
I agree with mindtools. Unles you are prone to siezures you should be fine at higher doses with Klonopins. Beer lowers it, but one or two wont hurt, just dont start in on the hard stuff:)

I have taken 800-1,000mgs everyday for a week with wellbutrin which also lowers threshold...I dont reccomend this, I was also taking 4-6mgs kpins a day. Nothing in life is certain, but the risk is far lower than street drugs, coke, meth etc...which people brag about all the time then turn around and say how dangerous tramadol is. You can have a seizure on lexapro .2%, its a strange drug because of its ability to work on seratonin, so for the right person its very nice, tolerance does build fast, but with me, all pain killers build up fast...which is a shame, in the 1950's that was frontline treatment for depression, if only you could find a drug combo/regimine to keep tolerance at bay.
 
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drivinthattrain said:
I have taken 800-1,000mgs everyday for a week with wellbutrin which also lowers threshold...I dont reccomend this, I was also taking 4-6mgs kpins a day. Nothing in life is certain, but the risk is far lower than street drugs, coke, meth etc...which people brag about all the time then turn around and say how dangerous tramadol is..
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The risk is "far lower than street drugs, coke, meth, etc?" C'mon son... do some research and stop spouting subjective <snip> beliefs on these harm reduction boards, you could seriously harm or kill someone with your misinformation.

Tramadol is the number one cause for non-epilepsy-related seizure admissions in the ER, for its unique ability to cause seizures by not only releasing serotonin (not blocking its reuptake like Lexapro), acting as a sympathominetic, and also as an opioid (M1 metabolite), all three of which actions increase seizure risk. You were incredibly <snip> careless for combining Wellbutrin and tramadol at those dosages; you certainly would have seized without those klonopins after a whole week of that stupidity.

If you had gained tolerance to the anti-convulsant effects of clonazepam, synthetix, which happens sooner than people think with benzos, then it would not help you as much as you would expect as far as avoiding seizures. Tramadol is a very dirty drug, and as much as I love it, I don't recommend anyone taking more than 250-300mg/day with a staggered dosage, and NEVER more than 200mg all at once.
 
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taking over 200mg at once seems pointless to me, id get much better effects from 200mg in the morning and then another 100 later on.
I work with an old guy who took 2000mg one day, and although he didnt seize, he was getting rather worrying tics and brain zaps, what an idiot.
 
ErgicMergic said:
The risk is "far lower than street drugs, coke, meth, etc?" C'mon son... do some research and stop spouting subjective bullshit on these harm reduction boards, you could seriously harm or kill someone with your misinformation.

Tramadol is the number one cause for non-epilepsy-related seizure admissions in the ER, for its unique ability to cause seizures by not only releasing serotonin (not blocking its reuptake like Lexapro), acting as a sympathominetic, and also as an opioid (M1 metabolite), all three of which actions increase seizure risk. You were incredibly stupid for combining Wellbutrin and tramadol at those dosages; you certainly would have seized without those klonopins after a whole week of that stupidity.

If you had gained tolerance to the anti-convulsant effects of clonazepam, synthetix, which happens sooner than people think with benzos, then it would not help you as much as you would expect as far as avoiding seizures. Tramadol is a very dirty drug, and as much as I love it, I don't recommend anyone taking more than 250-300mg/day with a staggered dosage, and NEVER more than 200mg all at once.
Click to expand...

You have no idea what you are talking about. I have been a Paramedic for 20 years. I have seen seizures from coke and meth all the time, Never one from tramadol. It becomes dangerous when mixed. I also posted I NO NOT RECCOMEND THIS, for harm reducation. Read entire post before making uneducated, insulting statements. Tramadol is not a dirty drug. Citation please. Tramadol is also molecularly similar to venlafaxine (Effexor) and has similar SNRI effects, http://en.wikipedia.org/wiki/Tramadol please read about this drug before scaring people <snip>. You gain tolerance to the seditative effects of kpin not to the anti-convulsant effects. Coke lowers your seizure threshold four times has much as tramadol and is not regulated, who knows what it can be mixed with. I have taken those doses without kpins and have not had a siezed. It is people like you who over dramatize misinformation they read off the internet with no pratical medical experince or formal education that reduces harm reduction on this site. I only reccomend taking as persribed, but advocate the use over street drugs, and the ignorance of people like you who read but do not comprehend. If you have a low seizure threshold, this drug is not for you. But stick to coke, and maybe ill see you while im administering Advanced Cardiac Life Support to you on the way to the ER.
Clonazepam may be prescribed for epilepsy.[8][9] Clonazepam is approved by the Food and Drug Administration for treatment of epilepsy. It is approved for treatment of typical and atypical abcences, infantile myoclonic, myoclonic and akinetic seizures [10] and also as a second-line agent. An open label study suggested that the combination of valproate, lamotrigine, and a benzodiazepine such as clonazepam could markedly reduce the frequency of drop attacks in patients with generalized or multifocal epilepsies.
<snip>
 
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Dude, I love tramadol but I can't be bothered to read that huge chunk of text.

Havign an addiction to tramadol AND benzos is possibly the worse thing you could do to yourself. Benzos are glorious little helpers for the tramadol withdrawal and benzo withdrawal is possibly the worse withdrawal of all drugs.
 
It amazes me how incredibly reckless some people are. Look, it's your life, do as you please, but keep your nonsense off of Bluelight. Just because you can suppress seizures with an extremely addictive dosage of clonazepam doesn't mean taking up to 20 times the intended dose of tramadol is even close to safe, you are seriously delusional and are justifying your reckless tramadol abuse by telling yourself that cocaine is more unsafe. Sure, cocaine is more dangerous, ODB died from an interaction of cocaine and tramadol, for instance, but that doesn't mean what you're doing is even remotely safe.

Don't take my posts personally, <snip>
 
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I did not say it was safe! I said I do not reccomend this and that dosage. <snip>
<snip>
I have provided citations for all facts, you have none, but opinions and insults, you need to keep that off bluelight, this is a site for education and harm reduction, <snip>
 
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Anoymator said:
Dude, I love tramadol but I can't be bothered to read that huge chunk of text.

Havign an addiction to tramadol AND benzos is possibly the worse thing you could do to yourself. Benzos are glorious little helpers for the tramadol withdrawal and benzo withdrawal is possibly the worse withdrawal of all drugs.
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take Tramadol on perscription only about three times a year, no withdrawals, usually as perscribed, sometimes recreational. I have been on benzos perscribed for 15 years, and will be for the rest of my life. This is not about addiction, its about debunking misinformation regarding overdramatization of Tramadol. I am a Paramedic, i treat benzo withdrawals every shift.
 
This thread needs to be closed. All information has been provided with links to professional fact based advice, there is nothing left to accomplish here except to bring the neurotics out from under their rocks.
 
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