Weed on a meth binge = short-term psychosis and a blackout?

[Jabberwocky]

You should probably get checked by a psychiatrist, a sub-recreational dose of dexedrine combined with weed with no sleep deprivation causing full blown psychosis is far from normal and pretty alarming. (Sure, it may cause some confusion and psychosis-like symptoms in some, but full blown "no clue where you are/word-salad spewing/everyone is out to get me" psychosis from that sounds alarming.)

it's not far from alarming at all. amphetamine triggers a dopamine release in the brain - which is "supposedly" the reason behind psychosis (at a higher level), coupled with cannabis which can trigger psychosis in individuals, (possibly though dopamine release too?) makes it no surprise that it could occur.

and yes it did happen - both times. word salad/there are police men watching me all around me/i am lost in a barrel full of ants (yes i said that, to my embarrassment)

the same goes for cocaine and me - if i smoked a joint as i was coming down it would actually WORSEN it and make the paranoia even worse.

i think that being said though, everyone's brain is different and reacts differently to drugs. i could just be a psycho - but in reality if i don't touch weed i'm safe. and alcohol. but thats another story.

i don't know the mechanisms of cannabis personally - i don't really study it, and when i do, i take a biased view in favor of it being damaging, as i have witnessed many people turn into absolute crazies when they hit the weed. worse than people who rail lines and lines of cocaine, and they still argue with me that it "relaxes them" and makes them "chilled" yet when you look at them.... god it's a sight. i'm more interested in the harder drugs that are being pushed to be extremely harmful yet when looked in depth you realize there's a really fine line on whether or not they truly are. it's never interested me or will - it's a plant that people smoke to get high, you like it or you don't, in my case i hate it.

if i ever smoke cannabis, even if i don't take my medication, i experience large scale panic attacks and extreme paranoia, regardless of the quality of the weed. if i ever smoke weed i have to have a benzo handy otherwise i turn a little crazy. but this runs in my family - my sisters who have both tried said it made them felt the same even when visiting countries where it was legal. it may be a genetic thing with weed.

sorry for going a little OT.

as to the OP - the meth will have played a huge part in the psychosis. sleep deprivation, dopamine depletion and cannabis's characteristics (the setting you took it in, your state of mind when you took it, which would have probably been fucking atrocious) will have all played a part in it.

 

[Achten]

I wonder why people think weed is such a great comedown drug, it usually sends people tripping balls. I remember after raves id always smoke cause my friends were but it would always make me feel anxious and spacey as hell unless i had a benzo with it. I think weed is the worst thing to have after a coke binge , or amphetamine binge. It just makes you think of such weird things and throws your anxiety up, benzo's ftw.

I use it because it partially brings back the magic after a psychedelic. And with amphetamines/coke it used to bring another layer of euphoria, imo. (Not that it doesn't anymore, I just don't use uppers anymore since I got to know psychedelics.)

 

[Renz Envy]

GHB is the only good comedown drug I've experienced. It takes the "strung out" feeling away and leaves you in a state of euphoria. You will sleep like a baby and it lowers your heart rate and blood pressure to a safe level. G has been studied to do the opposite of what amphetamines do to your brain and body; which makes it the perfect way to end a binge.

 

[JackiesBabyy]

GHB is the only good comedown drug I've experienced. It takes the "strung out" feeling away and leaves you in a state of euphoria. You will sleep like a baby and it lowers your heart rate and blood pressure to a safe level. G has been studied to do the opposite of what amphetamines do to your brain and body; which makes it the perfect way to end a binge.

I don't think GHB's mechanism of action is the opposite of amphs, because then it'd involve draining your brain of dopamine/noradrenaline/serotonin.

 

[Jabberwocky]

I don't think GHB's mechanism of action is the opposite of amphs, because then it'd involve draining your brain of dopamine/noradrenaline/serotonin.

theoretically renz is correct. it inhibits dopamine release, and controls it in time like way. so, if you have a dopamegenic drug (amphetamine in this case) producing more and more dopamine, GHB will not allow it to be released. how this would help on a comedown, i have no idea, as your depleted dopamine is what is causing a comedown. it also lowers glutamate and acetylcholine levels, of which amphetamines rise.

it acts on its own principle receptors in the brain and on GABA-B, which is what causes the sedation and lowered blood pressure (temporarily)

 

[JackiesBabyy]

theoretically renz is correct. it inhibits dopamine release, and controls it in time like way. so, if you have a dopamegenic drug (amphetamine in this case) producing more and more dopamine, GHB will not allow it to be released. how this would help on a comedown, i have no idea, as your depleted dopamine is what is causing a comedown.

it acts on its own principle receptors in the brain and on GABA-B, which is what causes the sedation and lowered blood pressure (temporarily)

Why is GHB considered recreational then? (I've never had it.)

 

[Jabberwocky]

because it acts on its own set of receptors in the brain, GHB, it's a really dose dependent curve as to what effect it has on your body.

it increases tryptothan levels - meaning more serotonin. it acts on its own receptors which are actually stimulating along with GABA-B which is where the sedative element of it comes from.

in low doses it actually stimulates dopamine release. at higher doses it inhibits it.

a lot of people using it to come down with get to sleep for about 2-3 hours before waking up a stimulated mess. it's just an awful drug.

it can in theory be considered a stimulant, but its essentially the same as alcohol, a dirty drug that makes you black out and lose your inhibitions, waking up on a pavement covered in your own faeces and vomit.

 

[JackiesBabyy]

it can in theory be considered a stimulant, but its essentially the same as alcohol, a dirty drug that makes you black out and lose your inhibitions, waking up on a pavement covered in your own faeces and vomit.

Which is why the only class of recreational drug I've never been addicted to and never will be are GABA-ergics.

 

[Jabberwocky]

well.. no... ghb acts on ghb receptors primarily, not gaba. it does to some extent but like i said its a dose dependent curve.

also, gaba-ergics aren't really recreational drugs... well.... it depends if you're talking about primary acting gaba drugs or not.

 

[JackiesBabyy]

well.. no... ghb acts on ghb receptors primarily, not gaba. it does to some extent but like i said its a dose dependent curve.

also, gaba-ergics aren't really recreational drugs... well.... it depends if you're talking about primary acting gaba drugs or not.

Benzos, alcohol, z-drugs, and etc. are what I was referring to when I said GABA-ergics

 

[Jabberwocky]

well.... alcohol is just a dirty drug that acts on everything in order to produce drunken messes. it is actually just a dirty drug, that blinds you if you take it pure. fuck that.
it literally acts on ever receptor in your brain. i fuck you not.

benzos and z-drugs aren't really recreational. they are in the sense they reduce and remove anxiety and put you to sleep - but i wouldn't say many people say - oh hey lets get fucked up on valium! because it wouldn't really do much apart from knock you out. if you have anxiety however, i can see how it is a very recreational experience.

 

[JackiesBabyy]

well.... alcohol is just a dirty drug that acts on everything in order to produce drunken messes. it is actually just a dirty drug, that blinds you if you take it pure. fuck that.
it literally acts on ever receptor in your brain. i fuck you not.

benzos and z-drugs aren't really recreational. they are in the sense they reduce and remove anxiety and put you to sleep - but i wouldn't say many people say - oh hey lets get fucked up on valium! because it wouldn't really do much apart from knock you out. if you have anxiety however, i can see how it is a very recreational experience.

Uh, I know lots of people who have and would say "Lets get fucked up on valium/xanax/etc.!" that find benzos recreational on their own.

 

[Jabberwocky]

they are probably anxious people, or just want to blackout from the world then.. doesn't sound very recreational to me really.
i'm anxious myself i've abused them once when going through bad times, but it was for the anxiety cure, and to black out from the world - not really a recreation purpose needed. just wanted to forget everything.

 

[Renz Envy]

a lot of people using it to come down with get to sleep for about 2-3 hours before waking up a stimulated mess. it's just an awful drug.

it can in theory be considered a stimulant, but its essentially the same as alcohol, a dirty drug that makes you black out and lose your inhibitions, waking up on a pavement covered in your own faeces and vomit.

I want to respect your opinion but I'm heavily against it. The only downfall I see to GHB use its the dose curve.

If one uses it to come down off of a stimulant binge, as little as a 9g overtime is enough to keep a person on the depressant side for hours until the half life of meth wears off. (You only need about 3g for 2-3 hours of healthy sleep)

Dirty drug? Alcohol is not naturally occurring in the body. GHB IS. At recommended dose GHB does not mess with the GABA-A receptor, heighten blood pressure or heart rate. It also releases growth hormone which is very beneficial to just about everything.

The body is no stranger to GHB consumption. Your body produces it naturally. Nausea and other negative side effects are considerably rare among users. Throwing up GHB is the sign of irresponsible overdosing. I have used and provided the drug to dozens of people and not a single one had a bad experience. I've used it for nearly a year. I've taken up to 4.5g of it. I never threw up or felt nausea.

If you use it, wake up on the pavement covered in vomit, then you have no right to ever consume GHB again. That just shows you have no control as a drug user. GHB is not "Baby's first drug". Users need to understand that you can easily go overboard if you're trying to get as fucked as possible. Like Mr. G says on another website "It is meant to be sipped on with caution."


Lastly, it is a good thing to combine with meth at the end of a binge, because it slows heart rate, lowers blood pressure, inhibits dopamine and will put you to sleep. I have provided it to many strung out individuals and they have all thanked me for saving them from a hellish experience.

When I was using meth, I slept and ate fine with the aid of GHB. Thus, no one ever suspected I was using meth for 5 months. I also maintained the same healthy weight.

Edit: Yes, a combination of meth and GHB is safer on the body than meth itself.

 

[Jabberwocky]

Well I've not personally done said acts with ghb, but I have witnessed them which is why I came to a conclusion of a dirty drug - not in the sense that it's not programmed for our body, but when it is taken in excess, it can lead to nasty results. I agree this is true of all drugs, but perhaps it's just a drug I don't like.

I did agree with you - it inhibits dopamine release hense why it may be good to use combined with meth, but a comedown is base on the depletion of dopamine and other chemicals that have been bombarding your brain while using them. Theoretically the inhibition of transport would allow for more dopamine to be regenerate and I guess I didn't look at it from that perspective. However, it does have a contradictory method of action, in that the stimulatory effects of GHB are dulled by the activation of GABA-B, and once that wears off you're left with the powerful ghb stimulatory effects - so surely sleep would be disrupted at some point? I am also unfortunate in that my GABA-B receptors do not make me drowsy. I have tried baclofen and phenibut, both of which did not sedate me.

Im sure it's a great comedown drug don't get me wrong. The fact that it does lower heart rate and blood pressure in a semi-natural way is much better than taking Xanax tbh. There is just a big scare surrounding ghb in the UK - in that it is a very dangerous drug and has to measured correctly to avoid problems.

 

[Renz Envy]

Well here's why it's not used often in medicine: Seizure Threshold
GHB can induce seizures while xanax does the opposite.

The stimulant effects of GHB can be frightening or fun. This is why it is not a beginner drug and should be used without knowledge of how it works.

Doses between .5-1g are mainly stimulant based and doses between 1.5 and up are depressant. Either way, as the drug is metabolized over 2-5 hours the stimulant effects will always be at the tail end. This dopamine release can either be exciting or terrifying. This is why users seeking to end a meth binge require more GHB. The stimulant effects of meth can also increase the dose needed to induce sleep.

I feel strongly about GHB, because I see it as a healthier, more positive alternative to alcohol (Much more clear minded). It is also my drug of choice and I've always tried to educate future users of the benefits and precautions.

 

[Jabberwocky]

Well I personally think any drug is better than alcohol anyway, so I'm with you on that one.

Indeed, GHB appears to be a much more intriquate drug that should be handled with caution. I don't suppose I'll get ahold of it anytime soon, I never really diverge into high dose stimulant land a lot of the time, and if I do I just stick to the simplicity.

However if I ever get ahold of meth I'll definitely be trying GHB - it sounds like an interesting mix, and possibly a very enjoyable one at that too.

 

[JackiesBabyy]

Well I personally think any drug is better than alcohol anyway, so I'm with you on that one.

I agree. Being drunk doesn't feel good once you've had a real drug, and drunk people are only fun to be around when you're drunk too. When you're sober they're just really fucking annoying.

 

[Renz Envy]

However if I ever get ahold of meth I'll definitely be trying GHB - it sounds like an interesting mix, and possibly a very enjoyable one at that too.

They really sort of cancel each other out. When using meth I would take around 3g of GHB and fall asleep or 1.5g to eat. I no longer use meth as I enjoy GHB much more and meth is a very negative drug unless used as a productive tool. But alas I stayed healthy and it was an enjoyable experience.

I agree. Being drunk doesn't feel good once you've had a real drug, and drunk people are only fun to be around when you're drunk too. When you're sober they're just really fucking annoying.

Very rude and annoying.

 

[Jabberwocky]

Hm.. Perhaps I should look into sourcing some ghb then.

And I agree with both of you regarding alcohol abusers- they are in my opinion the worst kind.