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  • PD Moderators: Esperighanto | JackARoe |

Why isn't mescaline used in psychedelic psychotherapy research?

I'm pretty suprised by it! Extracting the mescaline tones down the nausea hugely in multiple ways IMO, not only do you usually not have projectile style vomit for about 15 or more minutes if you chugged cacti, you really only have a once or so giant purge. Its really not to bad in comparison. Any 5HT3a antagonist will take away the nausea pretty much completely. I'm the person who mesc would usually make puke but everytime i've taken Ondan, its totally negated the effect even if I timed it poorly or did low doses. While I agree that it has weight against it, I feel psilo would have kinda similar ones honestly. It usually tends to atleast make me uneasy if not outright nauseated or puking. Psilo is also in my experience much, much, much rougher in nearly all regards. To me i'm in luck if I can find a soft place on psilo but even when mescaline is raging theres usually somewhere less rough to lay your head if you get what i'm saying. I'd rather deal with 20 puking people than 20 people ripping at medical devices/screaming about how their dying currently/having to admin benzos to them whereas 15 minutes prior to admin they could just IV an anti-emetic. Seems much easier to me, I would rather be given 1000+mgs of Mescaline with nothing else with 8+mgs of IV Ondan(or even nothing for better comparison!) than 15-20 mgs psilo IV with nothing! I would much rather puke for maybe 10ish minutes then be freaking out and possibly puking for 2-3 hours! I feel mescaline would have excessively huge benefits in psychotherapy its duration would be a hindrance but at the same time it could help, giving the patient adequate time to fully and totally work through difficult issues without the need to return to finish the job because they did it all in one session. Mescaline would be a bit more messy but in my mind I would rather deal with puke than the people losing it! ;)
 
The NBOMe's may actually prove useful because they don't last long and they feel nice.

Yess. Hopefully one day they will be properly studied. (along with everything else 8)). There is definitely some kind of enhancement with your ability to perceive images and ideas in your head. All while staying shockingly sober as far as psychedelics go. Maybe in the future it will be viewed as a valuable tool.
 
Yess. Hopefully one day they will be properly studied. (along with everything else 8)). There is definitely some kind of enhancement with your ability to perceive images and ideas in your head. All while staying shockingly sober as far as psychedelics go. Maybe in the future it will be viewed as a valuable tool.

I agree, the fact that NBOMe's are already used as PET-tracers in preclinical studies bode well for the future of these compounds even if only for diagnostic purposes.
 
I wasnt aware it was such a recent development. Do you think psilocybin mushrooms have a longer history of use?

I think peyote has been used since ancient times - but it didn't spread beyond the mexican tarahumara and the huichol tribes who lived close to the desert where it grew until recently. I was surprised when I found out it only really spread north in around 1900 - my image of peyote was always north american plains indians sat in the teepee.

There's a couple of interesting books about the indians who tried spreading it round the north american tribes.
 
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