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Weed + 5-HTP = ....INSANE!

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SirRollsAlot

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Ok so after I ditched the antidepressant's and decided to try 5-HTP, it helped but I know it shouldn't be taken everyday for long periods of time, anyway after taking it lets say 2 weeks strait (or longer) when I would smoke I would be literally the most intense trip ever. The high was literally rediculious! It was usually unpleasant, breathing seemed hard and the world would melt before my eyes, it feels like your 75 feet tall, I would hear songs playing that weren't on! When under the influence of the mix it reminds me of a Rediculiously high Dose LSD trip, though they aren't too similar. Strange relation though, I stopped 5-HTP and was really turned off by Cannibas for a while (till now <3) yet the trips still stay in my thoughts, what the fuck happened!? I cant stress how absolutely fucking high I was and how intense I was tripping! CEV's OEV's audio Hallucinations, and the most intense head rush. Nothing like a normal weed high, even the most intense bud highs cant compare. This was around 4-5 months ago, any thoughts, questions, related experiences? Thanks BL!
 
5-htp will not have this effect with cannabis. sorry, you just smoked some bomb and got nice and lit. Probably from quitting anti-depressants. A lot of well informed people here will even doubt the helpfulness of 5-htp and recovery from rolling, or 'pre-loading' on 5-htp

You mighta smoked some synthetic cannabinoids, the high you are describing sounds like it could be that.
 
Damn could it be thAt I took 7.5 hits of LSD 3 days before these experiences? It carried on for about a good week though. I smoke a lot of pot, it wasn't just the weed high, or the "oh my god my weed is laced" it was something totally different. Anytime I smoked, any weed, any situation it was full on tripping balls
 
5-HTP inhibits seratonin production/release (dont quote me on that exactly), but it doesnt release nearly enough to give you any sort of noticable high.

How did you "ditch" the antidepressants? Were you on them for long? You cant just "ditch" an SSRI, you need to taper (and under very close supervision). If you just "ditch" the antidepressants, youre asking for a manic-depressive break, which I suppose could cause you to feel much "weirder" after smoking weed. Thats just a shot in the dark, but seriously, dont just "ditch" your antidepressants. Thats dangerous as hell.

It also sounds like you just got some nice weed.


Soures: I work in a medical clinic and smoke nice weed. Know dat feel bruh.
 
I only took the SSRI's for a week and said fuck that, that was like over a couple months before this happened though, it was not just good weed though, my friends would be totally fine and I swear, visually the world just melted, I was walking and got the most unexplainable visuals, I'd stare at something and zoom in on it and it would have things flying around it and look completely put of this world. I have smoked for years and had the best quality weed and to this day remember the day I got the highest I have on weed, this was no weed high. During one experience I had one of the most earth shattering/spiritual experiences and walked into a entire different realm. Someone try it, take 5-HTP for roughly 3-4weeks and smoke
 
5-HTP isnt the magic you think it is, im sorry to burst your bubble.
It could be a minor acid flash back brought on by the good weed, but I guarantee 5-HTP had nothing to do with your weird high.
 
Dude ever thought different day different mind state SAME OLD WEED effects and..... Possibly just maybe from everyone telling you ya might of gone nutz thinking 5-HTP is Jesus or some shit bro. No offense but it is simply not and just idk go lay down or something man.
 
Bomboclat said:
5-HTP isnt the magic you think it is, im sorry to burst your bubble.
It could be a minor acid flash back brought on by the good weed, but I guarantee 5-HTP had nothing to do with your weird high.
Click to expand...

I think it has alot to do with your medical history and the anti-depressants. I have used 5-htp to help put some serotonin back into my brain (or body whichever) after some mdma use and I smoke nothing but top shelve buds and have never experienced what you did my friend.

good luck!
 
i have took 5 htp for weeks while smoking quality cannabis heavily daily and i never noticed any difference's other than having a little bit more energy than usual, same with 2 roommates i was living with at the time. although i know we are all different.

ime after i use other drugs like psychedelics, mdx compounds and benzos/opiates my cannabis high will change. also if i dont use any other drugs for a while my cannabis high will also change.

i havent touched any benzos in a couple weeks/ havent done any opiates for close to 2 months and iv been getting ALOT higher lately.
 
clarification on 5-htp. It does nothing in terms of inhibiting or releasing serotonin. Its simply the chemical 5-htp (precursor to serotonin) It helps slightly raise your serotonin levels. Really good the day after rolling balls on E. Dont take it all the time. Its more toxic than anything. I take it only after rolling and as needed the few days after depending on my mood. :)
 
SirRollsAlot said:
Im guessing the LSD must have influenced the highs and just leave it at that.
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for whatever its worth about 3 or 4 days after a festival i attended during which time i ate over a 10 strip. i took a 1 day tolerance break, took one fat bong rip, and i was tripping nuts, couldnt keep my thoughts together. i for one am a firm believer in residual effects from LSD effecting my weed high. but thats just my 2 cents.

as far as the 5-htp goes im pretty confident someone would have figured it out long before this. what with all the hype around for those that like to get their roll on
 
I'm going to chime in on this thread.

I used to be a drug user, but nowadays im only into cannabis really.
Anyway, when i first started a Joint used to be too much for me.

I actually used to roll a 0.1g joint for myself and i found the effects strong and effective , as well as the euphoria.

I live on a high-Tryptophan diet, which i would imagine would be similiar to taking 5-htp.
I believe it gives you a very slightly different high/effects.


Same as if you take melatonin and get high.
 
5-HTP is cardiotoxic unless co-administered with an enzyme inhibitor (eg. carbidopa) to prevent decarboxylation in peripheral tissue.

Do not expose yourself to 5-HTP, it is bad for your heart!
 
Roger&Me said:
5-HTP is cardiotoxic unless co-administered with an enzyme inhibitor (eg. carbidopa) to prevent decarboxylation in peripheral tissue.

Do not expose yourself to 5-HTP, it is bad for your heart!
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That's a vast overstatement. This theory comes from the fact that excessively high serotonin levels have been linked with cardiac fibrosis. A relationship was shown with consistent daily use over an extended period of time of high doses of certain drugs which act as agonists at 5-HT2B receptors in the heart in addition to their intended sites of action elsewhere in the body. The main culprits were weight loss drugs such as fenfluramine and chlorphentermine, and Parkinsons drugs such as pergolide and cabergoline, which were taken several times a day for years at a time (and even then not everyone got cardiac fibrosis). Stopping the drugs generally healed the damage. 5-HTP has not actually been reported to be associated with cardiac fibrosis. However, just to be on the safe side, when it is prescribed by doctors in huge doses long-term, they will sometimes co-administer it with carbidopa, as carbidopa ensures that only brain serotonin levels are increased so that there won't be excessive blood levels of serotonin and side effects can be avoided. I highly doubt taking 5-HTP once in a while is going to damage your heart.

Bomboclat said:
5-HTP inhibits seratonin production/release (dont quote me on that exactly)
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No it does not, it is a precursor for serotonin so it allows the body to make more serotonin.

Bomboclat said:
5-HTP isnt the magic you think it is, im sorry to burst your bubble.
It could be a minor acid flash back brought on by the good weed, but I guarantee 5-HTP had nothing to do with your weird high.
Click to expand...
I don't see how you can "guarantee" that. Everyone responds to 5-HTP differently, personally I have definitely found it to have noticeable effects when co-administered with certain drugs, during the "come-down" phase, or the next day after psychedelics. It could easily have had something to do with the LSD/cannabis/5-HTP combination.
 
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SirRollsAlot said:
Damn could it be thAt I took 7.5 hits of LSD 3 days before these experiences? It carried on for about a good week though. I smoke a lot of pot, it wasn't just the weed high, or the "oh my god my weed is laced" it was something totally different. Anytime I smoked, any weed, any situation it was full on tripping balls
Click to expand...

Did everyone else just skip this or something?

That's one of the magical miracles of weed my friend. The only time I'll say weed is a gateway drug is when I'm referring to the gateway that it opens allowing you to grab ahold of near memories of good acid.

This thread isn't about 5-htp, its about this guy trying to make sense of the mystical world we live in.
 
MonKeYDNA said:
Did everyone else just skip this or something?

That's one of the magical miracles of weed my friend. The only time I'll say weed is a gateway drug is when I'm referring to the gateway that it opens allowing you to grab ahold of near memories of good acid.

This thread isn't about 5-htp, its about this guy trying to make sense of the mystical world we live in.
Click to expand...

Okay the first part I agree with, totally could be a trippy weed induced flash back, used to happen to me regularly after shrooms or lsd and then smoking...

But that last part... lol. That's what this thread is about?
 
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