hello, I just recently came upon 4 methadone 10 mg tablets, I have never taken methadone before but heard it can be very dangerous If taken incorrectly. First off, I'm about 6 ft 150 lbs and take an average of 90 mg of oxycodone a day. Today I have taken about 40 mg of oxy a couple of hours ago and am currently out of everything but the methadone. I was wondering if it is ok to mix the two in the same day and what dose I should take my first time? Thanks.
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BDD Moderators: Keif’ Richards
First time methadone, concerned about dosage and mixing with other opiates
- Thread starter Mcrt24
- Start date
Well, methadone is certainly a very sedating opioid with a fairly high side-effect profile. It is fully synthetic, which can lead to more of a different opioid high. What you must remember with methadone is that it takes a very long time to peak in comparison with other opioids or any other drugs, really, and so re-dosing too soon can be very dangerous. I don't have any personal experience with methadone, but I would certainly exercise caution upon trying it. Even though you have some oxycodone tolerance, you might not be as tolerant to an equipotent dose of methadone, so I would start with a rather low dose. Again, it is more sedating and noddy than oxycodone would be. I would wait until the oxycodone has worn off subjectively (until you can't feel the oxycodone anymore), and then try a very low dose. I'd start with just 2.5 mg methadone to be on the side of caution, and wait several hours before re-dosing if you feel the need, only then re-dose with another very low dose. Methadone will exert effect for a very long while, hence why dosing once a day can be effective for those on MMT, so be extraordinarily cautious about taking the next dose.
Personally I would not combine the two. Whenever you take a drug for the first time you should not take it in combination with anything (with the exception of maybe taking a very small dose of a benzo during a comedown from a stimulant). You have to figure out how the drug effects you on its own before considering a combination, and even then you have to proceed with caution.
The oral BA of Methadone varies widely in individuals, so the best we can tell you is to start low, and work your way up. Given your tolerance, we can tell you what dose you should be safe to start out on though. You should be safe to start out at 10mg, and that's the max I would start at. If after an hour or so (and you really have to wait over an hour since it takes a while to peak) you find that you require a higher dose, then take another 2.5-5mg, depending on how much more you think you need. Do not increase by more than 5mg. The maximum dose that you should end up at is 20mg. I would not take more than that, as it is not really safe to. You may not find methadone to be that euphoric, so increasing the dose in an attempt to achieve the desired effects may cause you to end up taking too much, so if you reach 20mg and don't find it to be that good, then do not take more, and chalk it up to you not liking methadone, and save the rest for later down the line if you need it for withdrawals.
Quoted for importance.
Recommending dosages is fine, as long as it is for HR purposes of preventing them from taking too high of a dose.
The oral BA of Methadone varies widely in individuals, so the best we can tell you is to start low, and work your way up. Given your tolerance, we can tell you what dose you should be safe to start out on though. You should be safe to start out at 10mg, and that's the max I would start at. If after an hour or so (and you really have to wait over an hour since it takes a while to peak) you find that you require a higher dose, then take another 2.5-5mg, depending on how much more you think you need. Do not increase by more than 5mg. The maximum dose that you should end up at is 20mg. I would not take more than that, as it is not really safe to. You may not find methadone to be that euphoric, so increasing the dose in an attempt to achieve the desired effects may cause you to end up taking too much, so if you reach 20mg and don't find it to be that good, then do not take more, and chalk it up to you not liking methadone, and save the rest for later down the line if you need it for withdrawals.
Quoted for importance.
Recommending dosages is fine, as long as it is for HR purposes of preventing them from taking too high of a dose.
Ehhhh... Still Iffy about methadone..
Thank you all for the responses. So its been about 5 hours total. I took 7.5mg first after all oxy wore off, 3 hours later did not feel a thing and took 5mg more. I feel a little heavy in the eyes, nothing much though? I do have to say that my current oxy daily dose is down significantly as of 3 weeks ago I was around 150-180mg of the oxy 30s and some days up to around 250mg depending. The 90 Is what I'm currently down too. I have read though that methadone can take 5-6 hours to peak, Is this true? Will the effects kick in more or am I SOL? I'm up to 12.5mg over 5 hours been about 1 1/2 since I up'd from 7.5 to 12.5. Is the dose to low?
Thank you all for the responses. So its been about 5 hours total. I took 7.5mg first after all oxy wore off, 3 hours later did not feel a thing and took 5mg more. I feel a little heavy in the eyes, nothing much though? I do have to say that my current oxy daily dose is down significantly as of 3 weeks ago I was around 150-180mg of the oxy 30s and some days up to around 250mg depending. The 90 Is what I'm currently down too. I have read though that methadone can take 5-6 hours to peak, Is this true? Will the effects kick in more or am I SOL? I'm up to 12.5mg over 5 hours been about 1 1/2 since I up'd from 7.5 to 12.5. Is the dose to low?