The Big & Dandy 25I-NBOMe Thread (2nd edition)

[dextrous]

Ive asked this several times without an answer. Assuming the ratio above and blotter being able to hold 1mg of material per square doesnt this mean you could only lay 100mcgs per square?

no you would make a solution that has 500ug per 1mL. Simple as that.

 

[Tabtastic]

no you would make a solution that has 500ug per 1mL. Simple as that.

I'm making 1000ug per hit, so can someone check my reasoning?

You need 9g HPBCD/1g 25i. At 10g of this HPBCD-25i mixture to 10,000mL of grain alcohol. 10g/10,000mL=1g/1000mL=1mg/1mL. So the concentration at that point would be 1000ug/mL and, assuming the blotter had an absorption rate of 1mL/1cm square, you would have ~1000ug in each hit?

But maybe I'm wrong and all that matters is the 25i solute and there should only be 1000mLs of grain alcohol added? Because 10,000 seems like a hell of a lot just for 1g of 25i. I know concentration is solute/solvent but idk if the HPBCD factors into the "solute" end of that - I imagine it would since it IS what makes the 25i actually soluble in the first place. Thoughts?

 

[Jesusgreen]

After doing 5mg during 12 hour period I noticed my big toes were blue and pale. Anyone heard/experienced anything similar? I have heard high doses of Bromo can lead to loss of toes and fingers.

Sounds like prominent vasoconstriction. At such a high dose I wouldn't be surprised you experienced that.

Not all signs of vasoconstriction necessarily mean you're in danger of losing your limbs, but it's a sign you're putting your body under stress and that you're getting into a dose range that doesn't interact well with you. I'd avoid dosing that high in future, and also avoid combining with stimulants and anything else that causes similar vasoconstriction.

 

[klondike_bar]

I'm making 1000ug per hit, so can someone check my reasoning?

You need 9g HPBCD/1g 25i. At 10g of this HPBCD-25i mixture to 10,000mL of grain alcohol. 10g/10,000mL=1g/1000mL=1mg/1mL. So the concentration at that point would be 1000ug/mL and, assuming the blotter had an absorption rate of 1mL/1cm square, you would have ~1000ug in each hit?

But maybe I'm wrong and all that matters is the 25i solute and there should only be 1000mLs of grain alcohol added? Because 10,000 seems like a hell of a lot just for 1g of 25i. I know concentration is solute/solvent but idk if the HPBCD factors into the "solute" end of that - I imagine it would since it IS what makes the 25i actually soluble in the first place. Thoughts?

two problems stand out.

1) in my experience, 1cm^2 area of paper will not hold 1mL, especially if scaling to 100cm^2. you should fit about 0.2-0.4mL in a square centimeter at most. for reference, most blotter sheets of 900 hits (about 20cmx20cm in size) will absorb about 30-35mL of liquid.

2) with this in mind, you will have a significant amount of complexed chemical in your liquid, possibly making it slightly viscous. it can still be done, but conversion to citrate or acetate salts will add only a minimal amount of extra mass and are *presumably* simple to do (i tried once and got an unsatisfactory/unexplained result, and hope to repeat with proper ratios soon)

 

[Jesusgreen]

So a friend is graciously providing me with 3x 1mg blotters, HPBCD complexed.

Thoughts on taking 1mg first then 2mg another time vs taking the entire 3mg in one trip?

Alternatively I may split it in three and go for something like:
First time - 1mg 25I-NBOMe
Second time - 1mg 25I-NBOMe + 100mg MDMA OR 150mg 6-APB
Third time - 1mg 25I-NBOMe + 5mg 2C-P OR 10mg 2C-E

Don't really want advice on the combos as I'll be able to judge for myself once having tried it alone what it'd mix well with and be able to estimate a good dose range, but yeah - am I going to be "fully satisfied" by the experience with 1mg? 2mg? Or should I take it all?

I look forward to hearing your opinions :D Thanks

 

[zn13bt]

I'd do only 1mg to start. Maybe even 500ug in case you turn out to be sensitive to it. The most I've ever done is 1.3mg, and it was pretty overwhelming at times. I can't imagine doing 2, let alone 3 Also there was a report a while back of someone having a seizure at 4mg (though this was insufflated, not on blotter).

 

[IamMe90]

So a friend is graciously providing me with 3x 1mg blotters, HPBCD complexed.

Thoughts on taking 1mg first then 2mg another time vs taking the entire 3mg in one trip?

Alternatively I may split it in three and go for something like:
First time - 1mg 25I-NBOMe
Second time - 1mg 25I-NBOMe + 100mg MDMA OR 150mg 6-APB
Third time - 1mg 25I-NBOMe + 5mg 2C-P OR 10mg 2C-E

Don't really want advice on the combos as I'll be able to judge for myself once having tried it alone what it'd mix well with and be able to estimate a good dose range, but yeah - am I going to be "fully satisfied" by the experience with 1mg? 2mg? Or should I take it all?

I look forward to hearing your opinions :D Thanks

Is this your first time? Try 1mg, I'm no stranger to high dosing and 1mg complexed blotter was very strong and perfect. Reactions to this chem vary wildly so don't start out at 3mg, you may be asking not only for an unpleasant experience, but a dangerous idiosyncratic reaction, as I'm sure you've read about those.

 

[klondike_bar]

So a friend is graciously providing me with 3x 1mg blotters, HPBCD complexed.

Thoughts on taking 1mg first then 2mg another time vs taking the entire 3mg in one trip?

Alternatively I may split it in three and go for something like:
First time - 1mg 25I-NBOMe
Second time - 1mg 25I-NBOMe + 100mg MDMA OR 150mg 6-APB
Third time - 1mg 25I-NBOMe + 5mg 2C-P OR 10mg 2C-E

Don't really want advice on the combos as I'll be able to judge for myself once having tried it alone what it'd mix well with and be able to estimate a good dose range, but yeah - am I going to be "fully satisfied" by the experience with 1mg? 2mg? Or should I take it all?

I look forward to hearing your opinions :D Thanks

start with 1mg. it is a dose that will work well for most people, and its the only safe way to test a new chemical. If you really want to start high, try 1.25mg. but i wouldnt go higher.

Ive tried it once with my gf, i had 1mg and she had 500mcg. Afterwards we concluded that 1.4-1.6 would be a good next dose for me, and 1-1.2mg for her (im generally a hard-head with phenethylamines)

 

[RR16]

So a friend is graciously providing me with 3x 1mg blotters, HPBCD complexed.

Thoughts on taking 1mg first then 2mg another time vs taking the entire 3mg in one trip?

Alternatively I may split it in three and go for something like:
First time - 1mg 25I-NBOMe
Second time - 1mg 25I-NBOMe + 100mg MDMA OR 150mg 6-APB
Third time - 1mg 25I-NBOMe + 5mg 2C-P OR 10mg 2C-E

Don't really want advice on the combos as I'll be able to judge for myself once having tried it alone what it'd mix well with and be able to estimate a good dose range, but yeah - am I going to be "fully satisfied" by the experience with 1mg? 2mg? Or should I take it all?

I look forward to hearing your opinions :D Thanks

I'd say 1mg with cannabis at 1 hour mark would blow your socks off. And maybe after that try 2mg without cannabis and see the huge difference. I have personally taken doses from 500ug to 5mg and I'd still say the first 500ug dose with cannabis at 1.5 hour mark was the strongest experience.

I can't imagine doing 2, let alone 3 Also there was a report a while back of someone having a seizure at 4mg (though this was insufflated, not on blotter).

I have taken a lot of 1.5mg doses and once 2mg. Nothing special really. 0.5-1mg with cannabis smoked at the peak is 10 times stronger. I have even taken 5mg with only my big toes starting to show signs of vasoconstriction.

Once you smoke weed at the peak you won't be able to tell the difference whether your eyes are open or closed. You can get really lost into though loops and then snap back to reality. Like: "shit I had eyes closed for all this time? :O" It's the most awesome feeling I have sofar gotten with my drug experiences.

 

[omicamushroom]

JG...

I'd say go for 500 mics to start. Then wait a couple weeks, then try out 1mg... Then after another couple weeks or whenever you get around to it, and you should probably plan for it, do 1.5mg. I'm not so sure I would combo this would anything. I suppose if you won't too. My advice to anyone is to try out your chem in different levels on its own before mixing it with other stuff, and mix it with stuff you are already very familiar with.

Also... it seems as though there is a lot of this going around. Lots of vendors selling it quite cheaply. I think it will replace DOx and 5meo-amt blotters as the (replacement) "acid". What I'm saying is, more will find you probably. People will buy large amounts, and at that point it will just exist in the hands of people around the world, getting traded round and round and round... There will probably be too much of it.

Well whatever you do... Happy tripping!

 

[zn13bt]

I have taken a lot of 1.5mg doses and once 2mg. Nothing special really. 0.5-1mg with cannabis smoked at the peak is 10 times stronger. I have even taken 5mg with only my big toes starting to show signs of vasoconstriction.

You must not be very sensitive to the effects of 25I then. Based on what most posters here are saying, 5mg would be an overwhelming dose for most people, and potentially life-threatening too.

Today I tried taking 500ug of 25I along with 800mg of piracetam to see if it would potentiate it. It did, it feels more like an 800ug dose to me, but there's also been this weird undercurrent of uneasiness throughout the whole experience and I didn't get any of the happy mood lift that I usually get on 25I. It doesn't feel like the two combine that well to me. I'll see how I feel tomorrow, hopefully the piracetam will help with not feeling too burned-out.

 

[Transform]

This stuff won't be rare for a while at least. Its oral inactivity is actually pretty good as it should hopefully help to prevent accidents and with a little luck it will remain largely unscheduled worldwide as others from the 2C series have.

I decided to give this a go this evening and rushed into it somewhat. I measured out 1300ug and took it nasally.

The comeup was pretty brutal, alerts within a couple of minutes and full blown visuals within 10 minutes. I was light-headed and couldn't walk well, had a lot of body load/energy and was quite concerned I had mismeasured and was in for the worst.

I lay in bed for about an hour listening to music and enjoying the typical delights a challenging and overpowering trip have to offer. At one point i was honestly worried I was going to spontaneously orgasm because a song was so wonderful. By the time I got up I saw it was an hour later, decided I probably wasn't going to pass out or die at least and was able to relax much more. I then watched a couple of episodes of futurama and ate some plain tortilla chips and at this point I was feeling much better with the physical effects having subsided.

The rest was a beautiful enjoyable trip with major oevs lasting around 6 hours and effects lasting a solid 8 hours. I would not be comfortable driving for 10 hours.

 

[zn13bt]

Also... it seems as though there is a lot of this going around. Lots of vendors selling it quite cheaply. I think it will replace DOx and 5meo-amt blotters as the (replacement) "acid". What I'm saying is, more will find you probably. People will buy large amounts, and at that point it will just exist in the hands of people around the world, getting traded round and round and round... There will probably be too much of it.

There's certainly been a lot of people popping up asking how to lay blotter 8)

The economics of this substance are staggering. It's so easy to buy practically a lifetime supply for yourself and a few of your friends too.

 

[Tabtastic]

There's certainly been a lot of people popping up asking how to lay blotter 8)

The economics of this substance are staggering. It's so easy to buy practically a lifetime supply for yourself and a few of your friends too.

And speaking of which can anybody answer my question? Simply just wanna know how much grain alcohol to use with 1g 25i and 9g HPBCD. Someone who lays lemme know.

 

[slo mo]

I'm sorry to just hop in here, but there are SO many pages to read...I'm wondering if someone can answer a few of my questions. I really apologize if they have been asked before but they are semi-specific.

I'm supposed to be getting a 10mg sample in the mail. My plan was to dissolve this 10mg in 1ml of iso alcohol, and drop it onto some blotter art I bought as a novelty a few years ago. Will 10mg fit in my 1ml of iso? I've been reading a few pages - is vinegar preferable? its the HCL not freebase.

I did a "dry run" with a 16 strip of my blotter art. I found that 1ml of my "solution" (just the iso) is equal to ~40 drops from my dropper, give or take one or two depending on how close I get to the line. My math says 10,000 / 40 = 250 - I'd much rather have smaller doses like that and work my way up. So, I have that much figured out at least.

I did find however that my blotter is NOT very absorbent. I only dropped 1 drop on each of the 16 hits, and when I lifted it up, it was sitting in a pool of the solution. Obviously this is NOT preferable. Would it be better to just drop it on sugar cubes and do it that way? I was really hoping for the convenient storage of a blotter...but I'll do whatever I have to do I guess. If you guys could maybe suggest something that'd be great - but it looks like a lot of people are having the same trouble as I am.

I'll keep reading this thread, but any help you can offer me for my situation would be MUCH appreciated

Don't waste your time with blotters. Just nasal drip only 1mg worth of a 10mg/ml solution with an insulin syringe with the needle pulled out. Just take your time with the dripping, and you will be set. I don't understand why people want blotters when the liquid is there to be had. IMPORTANT - don't start at more than 1mg with nasal drip. I read all these reports of people doing 1.5mg or more, and I couldn't imagine that as 1mg was insane

The syringe is accurate, and nasal drip offers excellent bioavailability. Safe researching

 

[IamMe90]

^Irresponsible advice, certainly a lot of people can dose 1mg nasally but a lot of people can't. I am no stranger to high doses of most psychedelics but 1mg of 25i nasally was far too much for me. 1-1.2mg buccally is really enough for me. Also, if you're dosing for personal use, just get water color paper (140lb) and cut out bigger squares and there should be no absorption problems. Cut them in thin, long rectangles and you can put the strips between your gum and cheek easily.

 

[klondike_bar]

And speaking of which can anybody answer my question? Simply just wanna know how much grain alcohol to use with 1g 25i and 9g HPBCD. Someone who lays lemme know.

I dont have actual experience with this mixture, but i do know that a blotter page (900 hits, 7.5'x7.5') will absorb approximately 30-40mL. assuming that you want 550ug per hit, you *should* be able to dissolve the powders in 40mL of liquid. If this is unsuccessful, increase slowly to 60mL.

 

[twelvesevndi]

^i have also found that intranasal is a much more potent ROA for this chemical. starting at 1 mg that way is reckless.

i'd say 600 ug intranasal is equal to about 1 mg buccal.
so, if you are doing 25i for the first time and doing it in the nose, you really should not start at higher than 300 - 600 ug.

 

[Transform]

^Irresponsible advice, certainly a lot of people can dose 1mg nasally but a lot of people can't. I am no stranger to high doses of most psychedelics but 1mg of 25i nasally was far too much for me. 1-1.2mg buccally is really enough for me. Also, if you're dosing for personal use, just get water color paper (140lb) and cut out bigger squares and there should be no absorption problems. Cut them in thin, long rectangles and you can put the strips between your gum and cheek easily.

1.3mg nasally was arguably too much for me. I was fortunate in that I knew what to do but if I had been less experienced it could have been really unpleasant.

I would recommend 800ug.

Due to the incredibly fast comeup which can be very uncomfortable I would also suggest taking it in 3 portions over half an hour.

 

[porkstock]

is 25i-nbome really a FULL agonist? i thought it was a STRONG, but still partial agonist...but i could be wrong

edit: i was wrong. it is a full agonist, apparently.