I found this interesting:
6. Promethazine (Phenergan) Phenergan VC With Codeine Cough Syrup is a pleasant night time substance which can be enhanced with the green-label Alka Seltzer Night-Time Cold Medicine or diphenhydramine. See notes under metabolic enhancers - this drug theoretically will burn off a hydrocodone/oxycodone buzz faster while increasing sedation.
Here is the source. I imagine promethazine would react similarly with DHC, so try taking a lower dosage.
I'm not exactly read up, but doesn't it potentiate DHC in a different way to Hydrocodone, or are HC and DHC metabolized by the same enzyme? Or is it that it potentiates the nod, but kills the buzz, and would that apply to Dihydrocodeine?
Also, last time I used Promethazine (25mg) to potentiate DHC (260-300mg), i was nodding out massively, but when coming down from the DHC, i was very sweaty and restless, couldn't sleep even though I was on 2mg Xanax. I wondered if this could have been an allergic reaction to Promethazine, or just due to taking too high a dose of DHC while on the Promethazine?
Do people think I should cut the dose of Promethazine to 12.5mg and keep my DHC dosage the same, or keep the Promethazine dosage the same and cut my DHC dosage to (220-260mg OR even lower)?
Any insight would help!
DHC has a very long half life so it is possible some is lingering. If you got sick last night that means you took too much. Try taking 200mg next time. Although I would be careful doing that two nights in a row. I have found it is basically like topping up from the night before and made myself sick.
Also Madog I did wonder if that was the case, but I have an average tolerance as I've been using the past couple of weeks more frequently, my average dose tends to be between 200mg-300mg. I think it may have been the mix of Clonazepam and Xanax taken with the DHC, and my general gastrointestinal problems. See this is why I need to use the Promethazine so bad, not so much for the potentiation, more so for the antiemetic effect. The potentiation is a bonus!
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Report:
So, last night I was feeling kind of sick anyway, so took the Promethazine (25mg) early around 8pmish. Nodded off, and woke at 12pm and decided to dose. I started lightly (200mg) but wasn't feeling much after 45mins, slight sedation and a lil buzz. I think my tolerance must have sky-rocketed due to using the past 3 days.
Over the next hour I took 3 more 40mg DF118's and needless to say I was fucked. I was a little dissatisfied with the antiemetic effect of the Promethazine, I was still pretty nauseous, and itchy (though I don't mind the DHC/Codeine itches till the next day
). I was nodding nearly constantly, but feeling the full rush of the euphoria while nodding (usually when i nod it's like going into this lucid happy place).
My only big issue with Opiates, seems to be that I get terrible nausea whenever I smoke a cigarette (I'm a pretty heavy smoker) and I know some other users of Oxy seem to get this quite a bit, before people ask I've read that thread about how nicotine's MAO properties enhance the high very briefly and strongly. Whereas some people say it makes them want to smoke more, but I smoked about half a cigarette and puked a tiny amount - after doing Ket for lots of years being sick because of drugs doesn't bother me - because you usually feel so much better for it, but with Opi's the nausea never really seems to settle with me. Probably because my dose was too high (320mgs), and I do realise that the dose I did was probably a bit dangerous for a non-regular Opi user. But I had a whale of a time, one of my most euphoric Opiate experiences.
Around the 3rd or 4th hr, I nodded out and stayed out for a good hour or two. When I came around I had a banging headache and thought I was going to go to bed, so took 0.25mg Clonazepam. God knows what possessed me, but I decided to redose DHC, and ended up taking another 5 40mg pills. The come up wasn't as intense, and I just nodded out completely, and woke up when I started coming down. The redose was definately not a good choice, so I won't be doing that again.
As a conclusion to the thread itself, as said earlier on, really the Promethazine just exaggerates the CNS Depression of Dihydrocodeine, I also took a small amount of Clonazepam and was fine. Didn't get very much sleep though, very broken.
