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25I-NBOMe - Should we be dead?

J

jkro04

Greenlighter
Joined
Feb 21, 2012
Messages
1
Ok, now recently me and my friends have acquired, well, a fuckton of 25I. The tabs are HPBCD complexed (8:1 ratio) and give or take 1mg 25I. Since we have this fuckton of 25I, we decided the other night to take things to the next level. Over the course of one night, me and 3 other friends took 15 tabs while the rest of our group took normal human doses. We had waited more than enough time to have no notable tolerance, ended up tripping absolute tits for damn near 24 hours, slept another 15 hours afterwards and woke up feeling more or less fine. We were careful to monitor heart rate, hydration, body temperature, signs of vasoconstriction, everything seemed fine. This wasn't our first heroic dose either, but the other time was closer to half this dose.

Anyway, I've been trying to find something like an LD50 for 25I, but I can't find any solid information. I've seen some places saying that as little as 7mg could be fatal, but then an account where a man accidentally IMed 30mg and came out fine. So was this absolutely reckless? 2 days later, I'm experiencing barely more than a little fogginess, less than a night of MDMA use. Does anyone else have any experience with heroic 25I doses?
 
There is no way to say about any dose of it to be safe - everyone reacts individually and the substance has a broad range of individual reactions reported. From me injecting 30 mgs (of 2C-B-NBOMe) and getting off without consequences, to people having seisures from 1 mg, or even being hospitalised from 0,5 mgs (see drugs in the media). The only way to avoid individual negative reactions is to test the ground individually, starting low.
 
I accidentally took a bunch of 25i, i made a trip report in the trip reports section. I took however much can fit in 1ml of vodka lol, it was insanely overwhelming, the after effects were far worse than the trip itself though. I had very sore muscles for 4-5 days after probably due to vasoconstriction. It did not feel very safe to me but i was also not in a great state of mind. And the comedown was miserable. I also only tripped for about 12 hours total.
 
This wasn't our first heroic dose either, but the other time was closer to half this dose.
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What exactly is "heroic" about taking ludicrously high doses of compounds that have a very, very, short history of human use?
 
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Come on now, it's just a term, don't take it literally. You coulda just called him an idiot for taking a heroic dose lol ;P
 
true, it's not exactly heroic, but still, you can't expect me to believe that with 688 posts under your belt that you are unfamiliar with the term "heroic dose?" (of course you are familiar with it!)
 
The point I was trying to make is that taking high doses of psychedelics shouldn't be described as "heroic". I've always disliked the term but applying it to something relatively benign like mushrooms is worlds away from applying it to massive doses of research chemicals.
 
Taking unnecessarily high doses of drugs is definitely more idiotic than heroic ;) and 25i is not a chemical that I would push the limits with. The short history of human use coupled with its potency make me feel that this should be dosed accurately and conservatively
 
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abrad84 said:
The point I was trying to make is that taking high doses of psychedelics shouldn't be described as "heroic". I've always disliked the term but applying it to something relatively benign like mushrooms is worlds away from applying it to massive doses of research chemicals.
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Oh, I get the point, I just think it's a bit silly to rebuke someone for using a term based on a literal meaning that is no longer relevant. It's just part of the psychedelic lexicon, like it or not, people won't stop saying that, even when they don't mean to imply that they are really heroic.

Back on topic, though, no one can really answer the question of whether you SHOULD be dead or not, given how new the chemical is and how radically variable peoples' reactions seem to be to it. But yes, it was very stupid given recent news concerning dangerous individual reactions to it, especially since the dose you took was about 30x the dose that almost killed someone.
 
Should you be dead? We can't say. Should you be alive? We can't say.

These chemicals are extremely new and we don't have any toxicity information, other than some horrible dangerous experiences that people have had when taking inappropriately large doses.

What you did was extremely irresponsible and stupid and what's even worse is that you're asking this question now after you did it rather than before.

Something to remember too, is that an LD50 is not when doses start getting dangerous - it's when 50% of all people taking this dose will die. Even 1/10 of the LD50 can often be an extremely dangerous dose that can kill a large number of the people taking it.

This is not the way to enjoy psychedelics, and if you wish to experiment with "heroic doses" you shouldn't be looking to these new unresearched chemicals but to psychedelics that have years of studies and research into them such as LSD and Psilocybin Mushrooms. :)

Also, this'll likely be merged into the main 25I-NBOMe thread once you've had a chance to reply. :)
 
Jesusgreen said:
What you did was extremely irresponsible and stupid
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I wouldn't be so rough on him. There's no denying that he took a big risk, and put his own life on the line in pushing 25I to the limits -- but if someone wants to play guinea pig, that's their prerogative. Something positive *did* arise from his risky experimentation. The fact that he didn't suffer any immediately apparent physical toxicity is a piece of useful information.

Obviously I'm not recommending that people take potentially deadly doses of research psychedelics for the sake of science. But, it's his body, he knew that he was treading unexplored territory, he even monitored his vital signs during the experiment. I just would hesitate to call it "stupid".
 
I'm referring to the fact that he even mentioned that he'd heard 7mg could be fatal, and still proceeded with 15mg. Taking extremely high doses of a new chemical is risky enough, but doing it when you've already heard rumours that it can be fatal at less than half that dose range seems a tad more than unwise to me.

In future I think if someone were to attempt these kinds of high doses with new substances, the best route is to titrate upwards - jumping from regular doses to 15mg of something that is active in the microgram range would be like taking 10mg of 2C-E and then taking 120mg of 2C-E for your next experiment, it could be fraught with many risks - and it's even worse when multiple people are all doing it. If however you titrate up, and took 10mg 2C-E, then 12, 15, 17, 20 etc, you might find that you hit say 30mg and the side-effects outweigh the benefits - avoiding anything negative that might arise from the higher doses. In this case things worked out well, but really if one is to dose safely and responsibly they should titrate up :)

Of course OP this is no reflection on you as a person, we've all done some things that in retrospect were too risky and shouldn't have been attempted - I'm just glad you and your friends are okay and had a good experience :)
 
Good point JG. You know how might be considered heroes? People who take the time and responsibility to slowly and steadily increase their dose over multiple occasions (titration) and allowing enough time in between for tolerance to reset. Even then the term is up for debate, people who are in a home setting and are not checking their vitals and having an emergency plan etc, they may be pioneering the safety margin of a drug and sacrificing themselves to be the guinea pig.

Patience is the virtue here, diving in the deep end is not like taking one for the team. Stop thinking like that.

If done correctly (titration) it should be hard to die from it unless there are very harsh chronic effects, it would indicate something about the dose response curve but even then people still have to do their own titration themselves, each individual.

I have only taken 25D and 25C up to threshold doses and already confirmed that 25D does not sit well with me regarding cardiovascular effects.

Let's not glorify all of this too much, please. We should act like we are playing with fire because in some ways we are. Don't be impulsive or inconsiderate about your decisions. It should not matter that you have a large quantity, this is not candy you should be digging in to. All the warnings still apply so use caution for gods sake.
 
So...do you want to be the first person (well, not first in the case of 25I) to find out the LD50?

Cause that would be useful to the rest of the community...except when more phens get banned. its because of shit like this that bans happen. Dont try to "take it to the next level". If youre doing it, use already illicit drugs. Like lsd. Why not take a fuckton of lsd and see what happens? This is what ruins the research chemicals.

Sorry, that might be harsh. but its true.
 
jkro04 said:
Anyway, I've been trying to find something like an LD50 for 25I, but I can't find any solid information. I've seen some places saying that as little as 7mg could be fatal, but then an account where a man accidentally IMed 30mg and came out fine. So was this absolutely reckless? 2 days later, I'm experiencing barely more than a little fogginess, less than a night of MDMA use. Does anyone else have any experience with heroic 25I doses?
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Yes. Absolutely. Andthensome.
 
FractalStructure said:
So...do you want to be the first person (well, not first in the case of 25I) to find out the LD50?

Cause that would be useful to the rest of the community...except when more phens get banned. its because of shit like this that bans happen. Dont try to "take it to the next level". If youre doing it, use already illicit drugs. Like lsd. Why not take a fuckton of lsd and see what happens? This is what ruins the research chemicals.

Sorry, that might be harsh. but its true.
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Prohibition ruins things. End of story.
 
"over the course of a night"

NBOMes build tolerance really quickly so I expect this would have helped keep you safe. I've seen several reports that additional doses only increase duration, not intensity.
 
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