Shady Kaity
Bluelighter
how can i potentiate vyvanse after ingestion?
nope^ taking antacids before vyvanse won't help as lis-dexamphetamine must go through first-pass metabolism in order to have any effect. in the liver, enzymes cleave off the lysine molecule, and the resulting dextroamphetamine is absorbed through the first intestine. antacids or sodium carbonate only potentiate amps that are absorbed in the stomach i.e. dextroamphetamine (but NOT lisdex ofc) and methamphetamine
^Indeed.
Baking soda (sodium bicarbonate) and Tums (calcium carbonate) are both antiacids and urinary alkalinizing agents, so, at least in theory, they will poteniate even Vyvanse. They still have to be taken before the Vyvanse (or other amphetamines) are taken, however. A solid 30-60 minutes before taking the amphetamine in question is effective. Waiting longer is better, up to 90 minutes or so.
nope^ taking antacids before vyvanse will NOT help as lis-dexamphetamine must go through first-pass metabolism in order to have any effect. in the liver, enzymes cleave off the lysine molecule, and the resulting dextroamphetamine is absorbed through the first intestine. antacids or sodium carbonate only potentiate amps that are absorbed in the stomach i.e. dextroamphetamine (but NOT lisdex ofc) and methamphetamine