HydroMorphone Contin & Methods of administering

[Neuropathic1]

I am taking 2X daily 18mg Hydromorphone Contin, and 2 mg Hydromorphone for breakthrough pain. Out of curiosity I decided to open the 18 mg capsules and found tiny litttle beads. I crushed these and then added a small amount of water to dissovle them, I was left with a spoon of a milky white solution.

Is it safe to inject into muscle or fatty areas of the body? Will that help my pain better than swallowing?

As well, one instance I let the liquid evaporate away and I had white powder dried on the spoon. I took this powder and I tried snorting a line of it, I am not sure if I got much relief, but I was scared of possible OD.

I have a high tolerance from years of chronic pain management

For harm reduction and any knowledge of these methods would be greatly appreciated, Thanks in advance

 

[Supeudol]

I am taking 2X daily 18mg Hydromorphone Contin, and 2 mg Hydromorphone for breakthrough pain. Out of curiosity I decided to open the 18 mg capsules and found tiny litttle beads. I crushed these and then added a small amount of water to dissovle them, I was left with a spoon of a milky white solution.

Is it safe to inject into muscle or fatty areas of the body? Will that help my pain better than swallowing?

As well, one instance I let the liquid evaporate away and I had white powder dried on the spoon. I took this powder and I tried snorting a line of it, I am not sure if I got much relief, but I was scared of possible OD.

I have a high tolerance from years of chronic pain management

For harm reduction and any knowledge of these methods would be greatly appreciated, Thanks in advance

I am not sure about IVing these, although I know some people that do do this. I myself love HydroMorph Contin, and I open up the capsules and crush the beads up really fine and then I make nice lines and sniff the Hydromorphone. Since Hydromorphone has a better B/A when used Intranasally compared to Orally, this is what I would do. I believe the Intranasal B/A of Hydromorphone is around 51%.

 

[muvolution]

If you are a CPP, I cannot advise against injecting your medication enough. It will provide superior pain relief for maybe a week, then you will just be stuck (lulz) with a needle habit, and never, ever be able to go back to taking your meds regularly.

Really. don't.

 

[effie]

If you are a CPP, I cannot advise against injecting your medication enough. It will provide superior pain relief for maybe a week, then you will just be stuck (lulz) with a needle habit, and never, ever be able to go back to taking your meds regularly.

Really. don't.

Definitely this!!

If you absolutely insist, make sure you use a micron filter and go intra-muscular, not subcutaneous (into fatty tissue under your skin). But this would be a bad route for anyone to go down - let alone someone who relies on their medication to treat their pain.. Listen to muvolution.

Take a look at this injetion complications thread too..

 

[Neuropathic1]

Ya, Iam not going to IV....I can imagine after one does, when they revert back to normal pill consumption the effect will be hell after the brain has been flooded with all the drug. I can see me dying very easily too, given the fact my kidneys are only working at 25% efficiency. And all the potential problems look very frightening.

what about the chance of OD taken nasally? Thx

 

[effie]

Bioabailability of hydromorphone:

Intranasal: 52–58% (according to wikipedia)
Intranasal- 52.4%, Rectal administration 33% ,Oral-30-35% (according to this chart)

So nasal does have a higher bioabailability than oral - if you assume it's 60% (rounded up) and oral 30% to be on the safe side, you should take half the dose you normally would to get the same effects (or expect the same dose to be twice as strong..)

But really, I cannot stress enough that starting to abuse your pain meds in that way is asking for trouble.. nasal administration is obviously safer than IVing as a ROA, but it's still using a ROA other than the one you are prescribed, with a higher bioabailability, and if you start using them to get high you are risking going down a slippery slope (see muvolution's post).. as your tolerance rises you'd be tempted to up your dose more and more and the temptation to IV would grow..

I'm sorry, I don't mean to preach to you at all - but as this is a HR site I feel I have to say that I am really concerned that you'll end up running into problems that could jeopardise your future pain management..

Also, as you say, returning to your normal oral dose after using a ROA that gives twice the bioavailability wouldn't be much fun..

 

[muvolution]

you shouldn't be (that) concerned with the risk of OD in comparison to the risk that once you abuse your pain meds, no amount of medication or ROA is going to please you. Hydromorphone is addictive and compulsive. Without a doubt, the crack of opiates. Much stronger compulsion than heroin, and strong even nasally.

I cannot emphasize this enough.

If you want to get high off your medication, or are just looking for better pain relief, you have to earn it. Diet, exercise, acupuncture, alternative therapies, pt, rehab, tens, massage.... if you can use some non drug related methods to get your pain down, you will be way better off. At that point you will have less pain, so you will need less medication to manage it.

On average, opiates only give about a 20% reduction in pain, and a change in roa will temporarily help that, but you will return to a steady state within a few days.

 

[Neuropathic1]

Wow guys, I thank you for your wisdom. I really don't want to make things more complicated than they already are. It seems those other routes are nothing but stepping stones that are all too attractive and tempting. I am not sure if I could come back. I saw a program on H and they said if you snort it, you will end up injecting, and then you are done for. I know I would not have the will power. I really need to address my main problem of depression first, when in a depressed state,...I say fuck it, I don't care. If I can get the depression under control, I won't feel like throwing it all away. On the other side of the coin, I have a progressive illness that keeps getting worse and worse. I am near the end of my life now. agggrrhhh dualism of Smeagol vs Gollum syndrome!

 

[Addyman]

I am not sure about IVing these, although I know some people that do do this. I myself love HydroMorph Contin, and I open up the capsules and crush the beads up really fine and then I make nice lines and sniff the Hydromorphone. Since Hydromorphone has a better B/A when used Intranasally compared to Orally, this is what I would do. I believe the Intranasal B/A of Hydromorphone is around 51%.

Oral administration's mean bioavailability is 30%

Intranasal administration's mean bioavailability is 52-58%

Rectal administration's bioavailability is something like 35% +/- 25% (10-60% lol)

you shouldn't be (that) concerned with the risk of OD in comparison to the risk that once you abuse your pain meds, no amount of medication or ROA is going to please you. Hydromorphone is addictive and compulsive. Without a doubt, the crack of opiates. Much stronger compulsion than heroin, and strong even nasally.

I cannot emphasize this enough.

If you want to get high off your medication, or are just looking for better pain relief, you have to earn it. Diet, exercise, acupuncture, alternative therapies, pt, rehab, tens, massage.... if you can use some non drug related methods to get your pain down, you will be way better off. At that point you will have less pain, so you will need less medication to manage it.

On average, opiates only give about a 20% reduction in pain, and a change in roa will temporarily help that, but you will return to a steady state within a few days.

If Hydromorphone is the Crack of opiates

OXYMORPHONE is the PURE crack of opiates

just saying

 

[effie]

Wow guys, I thank you for your wisdom. I really don't want to make things more complicated than they already are. It seems those other routes are nothing but stepping stones that are all too attractive and tempting. I am not sure if I could come back. I saw a program on H and they said if you snort it, you will end up injecting, and then you are done for. I know I would not have the will power. I really need to address my main problem of depression first, when in a depressed state,...I say fuck it, I don't care. If I can get the depression under control, I won't feel like throwing it all away. On the other side of the coin, I have a progressive illness that keeps getting worse and worse. I am near the end of my life now. agggrrhhh dualism of Smeagol vs Gollum syndrome!

I'm sorry to hear about your illness.. I still feel you should try to keep your pain meds used as prescribed as you are likely to need them more and more - you'd hate to throw away that lifeline.. If you are struggling and want some emotional support coping with your illnes and depression, I would recommend coming over to The Dark Side forum (in my sig) - feel free to make your own thread, or we have a lot of resources in the TDS directory incuding a huge depression megathread. Good luckl