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Alternity
08-12-2002, 09:24
Well, it happened. The FDA finally approved Subutex for use as a detox aid in the good ol' US of A. Its only been 2 or so months since and I expect within the next few months a flood of Subutex pills on the street. It's Schedule III which makes me smile. This stuff will be very easy to divert from the pharmacies. So I ask for all the info you have on these 2 and 8mg wonders. Just how high are these doses for somebody WITHOUT tolerance? Can these be prepped for injection with at least marginal safety? What are the doses for oral vs. snorted vs. IVed? Has anybody seen these on the street yet? Prices? Will just anybody now be able to walk into a DATA certified Doctor and fein dependance to get a fairly potent opioid? For those of you who have abused Subutex, is it as good as it seems? A potent mu-agonist and kappa-antagonist. Does this mean its side effects are minimal compared to morphine? Is it really less addictive with a still strong high? And finally...(drumroll)...
Will the FDA soon regret their decision and either (a) bump it to Sch. II, or (b) say nevermind and take it back off the market for the purpose of detox?

Bonecutter
08-12-2002, 09:45
Wow, 2 and 8mg is a nice dose of buprenorphine. Thesubligual tabs overseas (brand name Tamgesic) are only .2mg. 2mg will really hit someone hard who doesnt have a tolerance.
Are they the freebase buprenorphine like the Euro version? If so, IV is possible you just have to use vinegar t dissolve it. .6mg is actually a very strong IV dose for someone with no tolerance. I've abused thehellout of these things and I dont think I ever dosed higher than .8mg at once.
And yes, buprenorphine is very nice. It's probably the only drug of it;s kind that I can do for days (all day) and suddenly quit without feeling like shit at all. It's very recreational. I'd take it over oxycontin, to be honest. The ruh from IV dmin is nice and the duration is even nicer. Also, tolerance seems to build up very slowly. For awhile it was my pokeable of choice.
Oral doses are a complete waste. Dont even try that. I dont know what happens but you will feel nothing at all if you eat'em. They're meant to be taken sublinqually. There's a definate technique to that. It's really not s easy asjust plopping it under you tongue. I cant remember if I ever snorted any. I slammed most of'em.
Are you sure it 2 and 8mg and not .2 and .8mg? I would imagine that 8mg IVed would kill someone really quickly. If they are putting out 8mg bup tabs there's gonna be a problem much like the one we had with oxycontin.
Maybe this Subutex brand will have some kind of aldulerant in it so it cant be IVed. That would suck cause IV is really the only way to go with this stuff.

synthic
08-12-2002, 20:47
I live in Sweden and have some experience from both temgesic and subutex. Both can be dissolved in water and IV:ed. You can also crush and snort the tablets. 0.4mg is a pretty decent amount for me, so a 8mg tablet lasts a long time.

Alternity
08-12-2002, 22:45
Two brands of Buprenorphine were approved for sale in the US on October 8th 2002. They are Subutex and Suboxone. Both come in 2.0 and 8.0mg strengths. Suboxone, however, also contains Naloxone to prevent IV use. Subutex is ONLY Buprenorphine, and a mighty high dose it seems. They are both for sublingual use. I like the way this is turning out so far. A couple more questions that I would greatly appreciate an answer to. What is the half life of Buprenorphine, or, how long is it in your system? Does it break down into Morphine? What is its metabolite? Is it detectable in drug screenings? If so, for how long? And what is the duration of the high?

Bonecutter
09-12-2002, 05:10
Tamgesic buprenorphine tablets are NOT water soluble.
Buprenorphine is metabolised to nor-buprenorphine, buprenorphine glucorinide and nor-buprenorphine glucorinide.
Half life of 35 hours.
Duration of effects: 8 - 12 hours :)
Alternity, you dont have to wait forthis stuf to hitthe streets. Online pharms sell it in the Temgesic tab. It's usually really cheap too.
[ 09 December 2002: Message edited by: Bonecutter ]

Alternity
09-12-2002, 09:08
Appreciate it. I'll look into it, although 8mg sounds much more tempting than .2 and .4mg. Um, so will those metabolites cause an opiate positive on an EMIT test? And if so, can it be confirmed with GC/MS?

Bonecutter
09-12-2002, 09:13
8mg should not be Ived. Trust me on that. I nod on .4 or .5.
I dont know bout the testing of bup.

Alternity
09-12-2002, 09:17
Drop me a line at alternity75mg@hotmail.com if ya could. I'd like to ask something that's inappropriate for this board.

ebeneezer_geeza
09-12-2002, 11:43
in UK 2mg ones are more than enough for someone with no tolerance.
BONECUTTER ARE YOU FROM THE US? If so would you mind if i email you a question - dont worry it aint for anything illegal.

Bonecutter
09-12-2002, 19:53
No, I dont mind.

Benzo-messiah
10-12-2002, 00:04
Ahhh Subutex... Buprenorphine is truely food of gods :) .
In europe the streets have been flooding of these nice 8mg tablets for a long while. At the moment buprenorphine is my choice of drug.
If you haven't got an opioid tolerance a sufficient dosage for a good nod would be something between 0.5mg and 1,0mg. If you wanna take it easy you can take just 0.2mg and definately feel it. The street price for these tabs is quite high (15$-30$, depending on various factors) but thw way you'll have to think of it is that one 8mg Subutex tablet compares to forty 0.2mg temgesics tablets so they aren't so expensive after all.
They are meant to be taken sublingually but i've found the best root of administration to be railing. I don't IV shit but that's supposed to give you the best high of these. What i do is just chop off little bits and pieces off the tab and crush them with my credit card and then rail the resulting powder. Even extremely small lines will kick your ass 'coz the tablet isn't that big and it compares to 40 temgesics.
The high lasts for ages and is really nice and mellow. The onset of buprenorphine is really slow, for me usually at least an hour. I often used to take too much because i thought the line i took first wasn't working and then had another. After doing that i usually spend the rest of the night in the toilet puking my guts out.
You don't get a rush like you do from smack. Instead you will slowly slip into a dreamy bliss state full of euphoria. I am using buprenorphine maybe a bit more than i should but it's quite hard to resist such a pleasant high. I usually take (snort) something around 1mg and it keeps me in the dreamland for the whole evening.
Smoking cannabis with it is really nice way intensify the high 'coz the two go so well together. Just don't smoke too much because when you're stoned out of your head you won't be able to take the most out of the euphoria Subutex provides.
Taking benzos with buprenorphine is a different thing. It intensifies the experience at least tenfold, no kidding. I usually take 30mg of diazepam (valium) or 3mg of alprazolam (xanax) with the intended dose of subutex. I usually time this by first snorting subutex and then wait 30mins before taking the benzos. This way the both peak at the same time and you will be left with a smile on yer face for hours. I highly recommend combining buprenorphine with benzos. It's better than heroin but that's just my opinion. It's not easy to accidentally OD on buprenorphine but please be sensible if you combine it with other drugs such as benzos.
If you are a heroin addict you won't get any recreation out of these. They just keep you away from witdrawing but they also help a lot for cravings. A friend of mine who used to be a hardcore smack addict is now in Subutex maintenance therapy. He gets 24mg of buprenorphine every morning. Thats three 8mg tabs, which to me would be an insane amount. Three 8mg tabs would easily last me over a month maybe even two because i don't do subutex on daily basis.
Buprenorphine is GOOD! It was anout time you yanks get it as well! :D :D :D :) :)

Benzo-messiah
10-12-2002, 01:36
[quote]Originally posted by Bonecutter:

Are they the freebase buprenorphine like the Euro version? If so, IV is possible you just have to use vinegar t dissolve it. .
The Euro version is indeed not a freebase. It can be slammed as usual. The whole tablet is water soluble since it's intended for sublingual use. There has been some articles in local papers about the dangers of IV Subutex. They say that some binders in the pill will block your veins in long term use.
I'm not into IVing but a lot of my friends bang subutex tabs and they seem to be healthy and no one's complained yet. I guess it's kinda similar issue as how safe is IV Oxycontin. It shouldn't be done but people do it anyway.

travis2600
10-12-2002, 17:28
[quote]Will just anybody now be able to walk into a DATA certified Doctor and fein dependance to get a fairly potent opioid?
Not in the US.

olav
11-12-2002, 21:27
To Bonecutter: Dude! Would you like to know what i just did? I iv:ed a couple of 0.4 mgs Temgesic (Buprnorphine) pills. Yes thats right they are injectable in contrary to what you say they dont need to be dissolved in vinager. They dissolve perfectly fine with plain water allthough you have to wait 3-4 minutes before they do. Alltough they can be dissolved faster if you use hot water and shake the syringe. As the pills are sublingual how did you think they dissolved under your tounge huh? IT WILL DISSOLVE IN ANY FLUID!!!
I live in sweden and here Temgesic and Subutex arent big news they have been out here long...

olav
11-12-2002, 21:33
Also they are NOT i repeat they are NOT detectable in urin-samples, yes you heard me correct. This is the perfect pill for people hwo like opiates and opiate-high but dont wanna become smack-addicts.

Bonecutter
12-12-2002, 02:03
Ok, I am wrong here. I cant seem to find any evidence that suggests Temgesic is bup freebase. I get boxes from the maufacturer that says"Temgesic (Buprenorphine 0.2mg)" You would think that it could say what salt of burprenorphine it is. A websearch says HCl.
They are a bitch to dissolve with straight water though and I'll always use a drop or two of vinegar.
As far as not being detected in drug screenings: That will come to an end shortly, here in the US anyway. I cant see any reasons why it's metabolites couldnt be detected. They arent tested for...yet.

johanneschimpo
16-03-2009, 12:35
I have a prescription for suboxone.

Lost and Confused
16-03-2009, 15:00
--^
Yeah me too. Since when is this a big deal?

Shlumpeet
16-03-2009, 15:50
I have a rather odd tolerance, I've only used it once and 2mg wasn't enough; though it seems if I would've taken more I would've felt amazing.

canadianchesirecat
16-03-2009, 15:59
Subutex, not subozone

One has naloxone in it which they claimed stops IV
Use: it doesn't but its in there, thus, a different drug

liquify
16-03-2009, 18:54
subutex is already so easy to get. nalaxone caused high enzymes in my liver so i was prescribed 8mg subutex. 8mg subutex are extremely hard to find they usually need to be specially ordered.

GbizzleMcGrizzle
16-03-2009, 19:05
what would be a good excus for a doctor to prescribe me subutex instead of suboxone?
I relapsed a few months back dodged a 1-3 yr bid in Louisiana state prison due to a paperwork erroe and i'm back in NY. Going back to my sub doctor but I'd like subutex I think the naloxone makes me kinda ill.

liquify
16-03-2009, 19:09
Say the naloxone affects your liver. That's how I got switched over... dunno if i can tell you that or not =/

Artificial Emotion
16-03-2009, 19:16
I have a prescription for suboxone.

Why did you bring back a seven year old thread from the dead to say you have a prescription for suboxone? Am I missing something?

daddysgone
16-03-2009, 21:08
Why did you bring back a seven year old thread from the dead to say you have a prescription for suboxone? Am I missing something?

because for all of his self-righteous and condescending posts, at the end of the day Chimpo is just as lame and thoughtless as those he bashes on a daily basis.
at least hes no longer a mod-although it was entertaining for me to witness the least amount of power ive ever seen go to someones head.

meh- im probably being unnecessarily mean-so ill say something nice. he does seem fairly intelligent, and has a good knowledge of drugs. :)

StaffWriter
16-03-2009, 23:11
Bup sux. Tolerance rises so high and fast and by day three, you won't feel a thing. At least that's the way it is with suboxone. And there's not much diff. between suboxone and subutex, minus the naloxone. I'm not sure what all the excitement is about. I have 60 subs sitting in my medicine cabinet.

2muchpain
16-03-2009, 23:17
sorry jc but unless you have been waiting since 2002 for your prescription i don't really see why you have put this here!!!

johanneschimpo
16-03-2009, 23:24
^ I wanted to see if 10 people would reply to a bumped 7 year old thread. Looks like they will. Thanks for being part of my experiment, guys.

2muchpain
16-03-2009, 23:28
^ok then you wierdo! Just wondered if i was missing something!

daddysgone
16-03-2009, 23:49
^ I wanted to see if 10 people would reply to a bumped 7 year old thread. Looks like they will. Thanks for being part of my experiment, guys.

so YOU bumbed a 7 year old thread too see if others would then post as well. You then condescendingly thank everyone for being part of your "experiment"
tell me exactly- what sort of experiment was this? You apparently sought to discover whether threads which YOU revive will prompt others to post as well?

This is just so boringly typical of you. Make a pointless post (a post that you would INSTANTLY jump on anyone else had they made it), and then talk down to everyone who was actually "dumb" enough to post in a thread you pointlessly bumped. Why exactly, are you such a douche? A better question might be, why do i care. Im not sure i can answer that- but i do know that you remind me of a mosquito with PMS and i find myself wanting to give you a wedgie. :)

johanneschimpo
16-03-2009, 23:55
^ I love your obsession with me. It's cute. <3

daddysgone
17-03-2009, 00:13
^ I love your obsession with me. It's cute. <3

i've called many an asshole, an asshole in my day. nothing particularly exceptional about you.
That said, that within this forum, you are really the only poster who i find irritating enough to comment on, should indicate to you how truly douchey you are.

johanneschimpo
17-03-2009, 00:29
^ Sweet man. You should be the vice-president of my fan club.

daddysgone
17-03-2009, 00:43
^ Sweet man. You should be the vice-president of my fan club.

why would i want to do that? i think ive made it clear that i dont care much for you. i would, however, consider taking you up on your offer if you would extend an olive branch-perhaps an apology? you could start small-maybe just a heart-felt apology to everyone for being such an obnoxious twit. then, you could move on to bigger things, perhaps expressing genuine remorse for existing.
nah- that's too far. but not being a condescending flapping vagina to everyone would be a lovely start.:)

mmmCHRISx
17-03-2009, 00:49
2-3mg suboxone gets me high, itchy and a bit noddy snorted.

How can .4mg of subutex make people nod? When its the same ingrediant as suboxone?

The naxalone in suboxone is only effectively active in doses when IVed, and higher doses of suboxone 16mg +

For this reason, people who do get high off suboxone never really exceed 4mg, because 8mg will get you high, but the naxalone will make you sick, and make the high weaker.

This is what i understand from my suboxone experiences, any clarification?!


BAHAHAHA JC! I love how your one liners make people so mad they throw a fit each post

StaffWriter
17-03-2009, 00:51
Ahhh fuck you jc!!! I didn't even notice. I love the way you just toy with us as if we are idiots. Are we not?

xxkcxx
17-03-2009, 00:53
^ I wanted to see if 10 people would reply to a bumped 7 year old thread. Looks like they will. Thanks for being part of my experiment, guys.

you are a douchebag, my love.

a lovely douchebag, but still a douchebag.

on the other hand, you got me to respond to this thread, so maybe you are just an evil genius.

daddysgone
17-03-2009, 01:04
2-3mg suboxone gets me high, itchy and a bit noddy snorted.

How can .4mg of subutex make people nod? When its the same ingrediant as suboxone?

The naxalone in suboxone is only effectively active in doses when IVed, and higher doses of suboxone 16mg +

For this reason, people who do get high off suboxone never really exceed 4mg, because 8mg will get you high, but the naxalone will make you sick, and make the high weaker.

This is what i understand from my suboxone experiences, any clarification?!


BAHAHAHA JC! I love how your one liners make people so mad they throw a fit each post

this information is not entirely accurate. as has been discussed many times, the nalaxone in suboxone is not active regardless of route of admin or dosage. the simple reason for this is that buprenorphine has a much higher affinity for opiate receptors then does nalaxone. therefore, the nalaxone in suboxone is for all intents, other then as a deterrent for those that do not know better, entirely pointless.

also, as to how .4mg of bupe can get somehow high, while it takes you 2-3 mg....tolerance is an easy to answer to that one. if you have any type of opioid tolerance, you will need more bupe to get you high, and for those with real opioid dependence, most agree that bupe really doesnt provide a "high", more of a slight mood lift. for those with no opiate tolerance, .4mg can be an adequate dose and provide a typical opioid high.

and lastly- JC remains a douche.

Too many doses
17-03-2009, 01:39
This is the internet why fight online??? Also the man aint Rush Limbaugh, Bill O'reily, or Anne Coulter so he cant be too bad. Also I second daddysgone on everything but the last line.

mmmCHRISx
17-03-2009, 01:41
Thanks for that, i guess most of the time i used bupe wasnt after my hard usage, it was after my easy-medium usage

daddysgone
17-03-2009, 01:43
This is the internet why fight online??? Also the man aint Rush Limbaugh, Bill O'reily, or Anne Coulter so he cant be too bad. Also I second daddysgone on everything but the last line.

I second everything you said but the last line:)

Too many doses
17-03-2009, 01:46
^lol.

OntarioGuy
17-03-2009, 01:57
this information is not entirely accurate. as has been discussed many times, the nalaxone in suboxone is not active regardless of route of admin or dosage. the simple reason for this is that buprenorphine has a much higher affinity for opiate receptors then does nalaxone. therefore, the nalaxone in suboxone is for all intents, other then as a deterrent for those that do not know better, entirely pointless.

also, as to how .4mg of bupe can get somehow high, while it takes you 2-3 mg....tolerance is an easy to answer to that one. if you have any type of opioid tolerance, you will need more bupe to get you high, and for those with real opioid dependence, most agree that bupe really doesnt provide a "high", more of a slight mood lift. for those with no opiate tolerance, .4mg can be an adequate dose and provide a typical opioid high.

and lastly- JC remains a douche.

Lmao at the last line...You guy's entertain me :)

Eight0Eight
17-03-2009, 04:29
Had a pretty bad relapse.

Switching back to Subutex tonight.

Wish me luck!

The "midnight breakdancing" has already kicked in.

2.28am - AND ALL FUCKING SUCKS.

daddysgone
17-03-2009, 23:32
Had a pretty bad relapse.

Switching back to Subutex tonight.

Wish me luck!

The "midnight breakdancing" has already kicked in.

2.28am - AND ALL FUCKING SUCKS.

so how was the switch back to subutex?? hope all is well. stick with the subs man, i promise it will make your life much better, and certainly more stable. even JohannesChimpo would agree...and hes a total douche. Now im just having fun:)

Eight0Eight
17-03-2009, 23:39
Heh.

It sucked.

I took a total of 12mgs - 2mg about every 2 hours till I felt as comfortable as sub could make me - but as was expected I still felt pretty shitty allday.

I managed to get to Uni and function well, so that was good.

But I flunked out tonight - and scored a 1/2 gram of H. I find that if I use a bit on the first day of Subs it doesn't get me high, but removes that left over sickness - if you know what I mean.

Hopefully I should be OK tommorrow on just the bupe. I'm not going to use on top for 2 days. It kinds of defeats the object!

daddysgone
17-03-2009, 23:45
^^^^^^^^^^^^^^^^

yea it does. may i ask, how are u taking the subs?? sublingually, snorting? if u are taking it sublingually, just make sure you keep it under your tongue for at least 15 minutes. ive met some people who just wait for it to dissolve and then spit it out. only a fraction of the bupe gets into your system if u do it that way. anyhow, stick with it- it really shouldnt be that bad, and u will quickly adjust.

Eight0Eight
17-03-2009, 23:51
I have tried shooting them in the past, but gave it up as I saw no point whatsoever - just smashing up my veins for nothing.

I seem to be getting the generic Subutex these days. They are weird. You put them under you tounge and nothing happens for a couple minutes, then they just sort of dissapear in seconds. I'm sure they are using different binders/fillers than brand name subutex.

But yeah, these days I only use them as directed, and I never spit out.

StaffWriter
18-03-2009, 00:14
this is the internet why fight online??? Also the man aint rush limbaugh, bill o'reily, or anne coulter so he cant be too bad. Also i second daddysgone on everything but the last line.

omg....8)

Too many doses
18-03-2009, 00:57
^what's the omg for? The coservative remark or the don't be a antisocial prick and fight people online you've never met as it shows you are frustrated with life one?