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What ever happened to PCP?

unodelacosa said:
I think you accidentally a word there ;)


Ooh, sorry, that sucks ass. You might have to just ride this one out. Smoke weed, keep your renal pH low and keep fluids moving through you. That should help flush it out. Maybe smoke some weed and/or put on some chill music. I'm gonna say put on either Madvillain's Madvillainny or OK Computer by Radiohead.

Or maybe Radiodread (OK Computer) by the Easy Star All-Stars.
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It was a rough ride and a pretty tough trip. I checked the bag today and what i took was closer to 100mg. Don't dose when intoxicated. I ended up having to take some benzos because I was starting too lose my shit. Even that didn't bring me down, had to take some seroquel.

It gave me some really disturbing thoughts, and the inner tension was very difficult. It was odd, i felt like it was finally wearing off, and then at midnight it starting surging back on. I could barely walk.

Some of the thoughts were particularly disturbing like into my mind popped the thought, "you know you are going to die by suicide, you might as well do it know". And it's probably true, I probably will die from suicide, not random emotionally driven suicide but self-euthanasia (if I were faced by a hopeless terminal illness or I'd probably euthanize by self).

However today I feel great, like my brain was reset. Which is astonishing because one of the benzos I used was temazepam, which always makes me feel absolutely miserable and depressed the next day. But today I feel better than I have in a while. Still, last night pushed my limits in a way that isn't worth repeating. I was pretty miserable.
 
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I don't know where from/to now, but available to me before Brexit from Holland and has been around for some years already is 3-meo-pcp.

Which from some v brief reading, user reports sounded like a safer, more predictable controllable but in nearly no way meagre consolation.

I think the real danger is deep sudden fast setting psychosis.

Hence as others say, Ket was brought in.

Except did horses used to be operated on with PCP?

Or vet ket was already in use before being unleashed on the recreational populace here UK in early 2000's before being fully replaced by the far far more user friendly, less holing pharmaceutical ketamine?


But if I did not have my well known allergy prohibitions, 2020 I would have grabbed a gram of pure 3-meo-pcp powder.


My advice is if ya's really wanna try pcp now, search a legit RC source for 3-meo.

However, these are actually dangerous drugs mentally, can quickly derail a firm mind bring on instant psychosis to levels relatively gargantuan levels of LSD unlikely to or in a different more easily functional management manner.

While IME pharmaceutical Ket abused upto even 5 grams a week, bladder and sinus, respiratory issues aside, somehow pretty safe as houses and untarnishing.
 
cdin said:
Interesting you don’t find it stimulating. I find it distinctly stimulating.
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RoA makes a big difference, I think. I will say that low recreational doses of n-methyl-d-aspartate receptor antagonists tend to prevent me from sleeping. I'm not stimulated though on them, it's more of a … mental response or awakening they evoke. They have an odd persistence to their effects. This has been true of 3-MeO-PCP, 3-MeO-PCE, 3-HO-PCE, 4-HO-PCP, MXE, FXE and a few others for me. So in that sense I guess there's some degree of stimulation. However, most of them can produce full anesthesia as well as something resembling the infamous K-Hole when you get the dose just right.

That's the key. Get the dose right and the reward is exceptional. Miss that mark and you'll pay for it, as @negrogesic will attest.

I'm rather fond of 3-HO-PCP which has affinity for the µ-opioid receptor roughly equivalent to codeine in addition to its NMDA-receptor antagonism. It's a profound psychedelic dissociative, but also an anxiolytic via this µ-opioid receptor activity.

When I smoke PCP it's often coupled with weed, and that no doubt influences my perception of it.
 
PCP is one of the drugs still on my bucket list. I’ve done 3- meo-pcp and Ketamine but never came across wet. I’m currently on a long term clean/sober streak but one day I shall partake.
 
I for sure find it stimulating. Feels like strong add DRI push to me.
 
cdin said:
I for sure find it stimulating. Feels like strong add DRI push to me.
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  • It's primarily an NMDA receptor antagonist (anesthesia + analgesia result).
  • PCP also inhibits nicotinic acetylcholine receptors (dreamlike psychedelia results).
  • Additionally it's a dopamine reuptake inhibitor with a Ki (nM) value of 347 for its IC₅₀ (so that checks out)
  • Just to compare DA reuptake inhibition (reminder: lower values = greater affinity, or i.e. "less is more")…
    • Cocaine has a Ki (nM) value of 211 (IC₅₀)
    • Ritalin (methylphenidate)'s value is 121
  • Also, do note that dopaminergic activity does not necessarily result in CNS stimulation.
 
unodelacosa said:
  • It's primarily an NMDA receptor antagonist (anesthesia + analgesia result).
  • PCP also inhibits nicotinic acetylcholine receptors (dreamlike psychedelia results).
  • Additionally it's a dopamine reuptake inhibitor with a Ki (nM) value of 347 for its IC₅₀ (so that checks out)
  • Just to compare DA reuptake inhibition (reminder: lower values = greater affinity, or i.e. "less is more")…
    • Cocaine has a Ki (nM) value of 211 (IC₅₀)
    • Ritalin (methylphenidate)'s value is 121
  • Also, do note that dopaminergic activity does not necessarily result in CNS stimulation.
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also i find for me, the stimulation increases w increased dose. a reasonable range dose 10-15mg will feel pretty ok, and ill sleep later in the night, not too crazy - mostly NMDA.
it's when ive crossed to the 50-100mg+ line that it REALLY seems to get uncomfortable and stimulating, at least for my personal experience.
 
cdin said:
also i find for me, the stimulation increases w increased dose. a reasonable range dose 10-15mg will feel pretty ok, and ill sleep later in the night, not too crazy - mostly NMDA.
it's when ive crossed to the 50-100mg+ line that it REALLY seems to get uncomfortable and stimulating, at least for my personal experience.
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Using which RoA, and is this your prefered route?
 
unodelacosa said:
Using which RoA, and is this your prefered route?
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generally speaking i like to vaporize it on some weed. I suppose insufflation would be more efficient, but it's FUN smokin it on green. If i got it now, i would for sure use my temp controlled vape and do it that way on a bed of plant material. but yeah, that's my preference. ive snorted a little, and eaten a little, but it felt less "fun" than the vaporized experience.
 
Yes, I have consumed PCP in many ROA's from around 1971 to 1995. Insufflation,smoking, orally, IV. It is a different experience depending on how you do it because of the way it comes on. If someone has particular questions I can try to give my experiences.
 
i did it as late as 2018, so it's gotta be out there.

my guy is behind bars, though... and i don't need to be hanging out with sketchballs anymore.
 
izo said:
is pcp vaped less potent than with any other route?
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First let me clarify a term: I didn't "vape" it as I dipped very small "popcorn" buds, so as to just make contact with the liquid (bottle). This allowed the bud to wick the PCP up, but it wasn't like immersing it entirely. The bud was then smoked in a small pipe. I'm not sure that we actuallly "vaped "it. Just being 100% up-front.

As to the potency, it was quite the opposite. If one insulflates PCP the come-up is measured in minutes, however when smoked as described it was very common to feel the effects while still you were still holding your breath. It was as if you were suddenly transformed into the "eye of a hurricane". Often, someone who had little to no PCP tolerance would be instantly teleported to a dream state that could be so lucid it might be difficult to distinguish the experience from reality.

If one bought "dippers" or sherms the potency would vary wildly, but straight uncut liquid PCP is "instant karma" if I ever experienced it.
 
I vaped tce and it was much less potent than snorted as a sidenote.
 
izo said:
I vaped tce and it was much less potent than snorted as a sidenote.
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I have never experienced tce. How would you compare it to PCP when snorted ?

Back in 1971, there was a crystal being distributed (as "rocket fuel" ) that when analyzed at a lab came back labeled as mis-synthesised PCP. You could smoke a "match head" of the crystal and be "tripping balls" but was in-effective orally or by snorting. Wish I had bought a shitload of that while it was available.
 
Never had pcp, but tce should be rather similar to pce, perhaps a bit less potent. So not that different from pcp.
I found it to be on par with ketamine which is my favorite arylcyclohexylamine.
 
The Hamilton's Pharmacopea episode titled 'a positive PCP story' could have had another thing added: it abolished a debilitating sense of disgust I had (just the thought of scat porn could leave me retching for ages. After considering how extreme my response was, on PCP, I no longer have that problem (but in no way ever want an image of that in my memory).
I'm convinced a lack of disgust is responsible for the horror stories (eg Big Lurch's cannabalism)
 
fastandbulbous said:
The Hamilton's Pharmacopea episode titled 'a positive PCP story' could have had another thing added: it abolished a debilitating sense of disgust I had (just the thought of scat porn could leave me retching for ages. After considering how extreme my response was, on PCP, I no longer have that problem
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This is where I find dissociative drugs to be most valuable – they allow me to analyze aspects of my life, habits, patterns, thoughts, feelings, and actions in a way that I normally cannot. I feel like dissociatives anesthetize certain difficult emotions and allow me to be critical and analytical in a helpful manner. In turn that's allowed me to unpack a lot of shit and let go of some baggage from the past I was holding onto for no reason.

It's easy to get caught up in a negative emotion thought loop and sometimes a dissociative can really cut through that bullshit. There's a reason Esketamine is being used in breakthrough therapy involving treatment-resistant clinical therapy, and the fact that it's an NMDA-receptor antagonist psychedelic dissociative drug like its pharmaceutical sibling, Sernyl, PCP, et al. is not a coincidence.

fastandbulbous said:
I'm convinced a lack of disgust is responsible for the horror stories (eg Big Lurch's cannabalism)
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No, I'm pretty sure it takes a lot more than a simple lack of disgust, though I do believe it's a component of the whole phenomenon. And that makes sense insofar as to consider how dissociatives tend to dissociate the mind from the body. That's the anesthesia part of the drug. It's just that PCP alone is not enough to make someone who is mentally sound as a pound suddenly become an unhinged lunatic cannibal.
 
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