Hello bluelight so I’ve stopped with my mdma intake since December of last year, but funny enough more recently I’ve experienced eye wobbles when listening to music especially when certain frequencies of bass or treble producing a more significant effect, but I can still focus my vision on demand while my eyes are wobbling.
I just find this kinda intriguing because I’m not taking any drugs to produce this effect other then maybe weed I guess. But when that bass drops my eyes be wiggling and I catch myself smiling.
I think this maybe a sign of neurological damage but I’m unsure.
This phenomena is well known by many people who have done a lot of MDMA.
Many people including myself when not under any amount of MDMA but listening to tracks that we really got down to in the club or at a rave years ago will feel ourselves start to actually roll.
Eyewiggles, that warmth pushing on your chest as you start to come up.
Of course it never develops into a full-blown role. It's just a tiny nibble at your toes like a little fish when you're at the beach.
This is a well-known phenomenon.
And don't worry about any neurotoxicity there is zero actual physical evidence of neurotoxicity in humans.
Before anybody on the board gets on me about that, the evidence used to support alleged neurotoxicity in humans is downregulation of the SERT binding affinity in prior users of MDMA and there's some evidence that the amount of downregulation is directly proportional to cumulative lifetime dose. But nobody wants to admit that the same thing happens to people on SSRI antidepression medication.
Why is it neurotoxic damage if it's MDMA but not if it's celexa?
I think reasonable human beings can figure that answer out for themselves.
In fact, as far as I am aware, they haven't even been able to confirm neurotoxicity in fatalities that involve MDMA.
I'm not saying it absolutely doesn't exist. But what I am saying is it would have been easy to do a little brain biopsy on fatalities that involve MDMA and prove terminal damage at 5-HT and dopamine neurons. But nobody's done it.
Neurotoxicity studies on rats and non-human primates where dose is of 10 mg per kilogram four times a day or more for multiple days in a row are used to extrapolate neurotoxicity to humans which is absolutely ridiculous.
MDMA is in phase 2 clinical trials and they already have evidence that recreational doses instigate the release of BDNF brain derived neurotrophic factor. That is the opposite of neurotoxicity.
As
@G_Chem said, in animals, pre-treatment protects against MDMA toxicity and it seems that intermittent small doses do not result necessarily in neurotoxicity.
I can't remember exactly what the break point is, but I would urge you to go read the research. But I want to say it's a cumulative minimum of 20 mg per kilogram per day for a minimum of two days before any significant neurotoxicity is seen.
Do I think that people should go around taking a gram of MDMA over the course of a rave? Absolutely not.
Do I have observable empirical evidence in the human organism that neurotoxicity is absent when doses are less than 500 mg in a day? Pretty much considering I've taken three and four pills over the course of an evening multiple times in my life sometimes on back to back evenings and I didn't suffer any neurotoxicity.
Admittedly, my physiology is likely unique because I never got the Monday blues or the Tuesday blues, I always had it multi-day after glow and never lost the magic.
There was one epic weekend where I found a bag of beans in between couch cushions at a rave in absecon, New Jersey. It was a Thursday or Friday night. It had 60 intact pills and what I assume is the crushed remains of the other 40. Someone's misfortune was mine My brothers, the chicks that we decided to let hang around with us in a few other friends Fun for the rest of the weekend.
I honestly don't know how I made it back home. We were in Atlantic City and then we ended up in Philadelphia where I was rolling into a shower in this really sketchy basement but the tub and shower were immaculate.
And then I remember hallucinating driving south on i-95. I thought I was driving on a bridge in the sky but it was just 495 or 295 through Delaware.
Made it home somehow. That was One of the very few times where I actually felt like I could have really got overboard.
It was a Monday and I didn't feel normal again until Thursday, but I attribute that to the fact that it probably took that long for my body to metabolize and rid itself of all that damn MDMA.
MDMA is a very forgiving drug.
A naive user of MDMA can take 200 mg on their first experience and have a wonderful evening.
Be a naive user and eat 200 mg dose of high quality methamphetamine and see what happens to you over the next 2 days.
It wouldn't even compare.
