http://motherboard.vice.com/blog/to-the-withcraft-plant-thats-spoiling-ayahuasca-tourism[/URL] that discusses risks and deaths associated with Toé (brugmansia) in relation to the rise in ayahuasca tourism. When it comes to pharmaceutical sources of this class of drugs there are documented cases of death from overdose on places like pubmed. When it comes to pure drug forms make sure you research what is considered the dosage range to stay under that is likely to be life threatening. Here is good example for diphenhydramine
http://www.ncbi.nlm.nih.gov/pubmed/11204550.
If you are going to try this class of drugs I suggest start small and if you need to work your way up in dose try gradually each separate trip. This is especially important with plants as it seems they may vary in dosage quite a lot."]
The first point I want to question is in regards to the point raised that the hallucinations from the anticholinergic deleriants are more "real" than any other class of drug. My own personal experiences disagree. Although the hallucinations I had from anticholinergics were different from any other drug I've experienced. Please let me explain. For example on high dose diphenhydramine I experienced hallucinations of people and proceeded engage in conversation with them for quite some time until they evaporated and I realised they were not real. This happened a number of times. I also spent quite some time involving complex tasks on my phone involving apps ect until it too evaporated and I realised the phone had been a hallucination. The room I was in and the surroundings that were all real including people and objects I could see that all as per normal. The fake people and objects I hallucinated appeared to be real and stayed visually and audually in tact in my otherwise actually real world until the fakes visually dissipated (evaporated) in front of my eyes. I was embarrassed to find that I was not paralysed such as in a dream or nightmare and was therefore talking and interacting with people and objects that weren't there for quite some time. This all happened in room with enough light to see everything that was going on. There weren't geometric patterns, pulsing colours or other notable visual distortions or effects as with classic hallucinogens.
I've had very real hallucinations from MDEA towards the later part of the experience. It's more like a dream I am in where I am unaware of reality and often in a totally different place with a different set of circumstances going on. I then snap back to reality and become aware I was just dreaming. This process can happen to me a number of times during one trip. For me the the dream episodes normally go on only for a moment or maybe a couple of seconds. Not long enough that a friend hanging out in my room to notice until I told him. In the normal reality my vision is usually a bit blurry and I often can make the eye wobbles happen (whole field of vision appears to shake a lot) such as when I look at poster on the wall and relax my eyes.
I've had hallucinations on MDA+MDMA that I thought were real for a second until I snapped out of it. Sort of a blurry mix of reality and imagination where low light or blackness probably played a part too. Such examples are staring out a car window at night as the red safety reflectors on the passing road poles passed by. For a moment the blurry red reflectors moving by became what I really thought was the red tail lights of nearby car. I suddenly snapped out of like a daze. Another time I just entered the my friend's apartment. It was a bit dark so I couldn't see too well. For just a moment a friend looked like he had a funny moustache and it all seemed kinda funny but I didn't know why. I snapped out of like a daze and could see more clearly. I could see that my friend was actually holding a big green bud up to his nose.
I've had friends and people I've met on 'messy' or trippy MDxx pills talk to walls, to thin air or even blurt out nonsense to a complete stranger. The friend who blurted nonsense to a stranger described an experience similar to my MDEA hallucinations. He was like in a dream for a second and he did something like grab someone he knew and talk to them. He snapped out of it to realise there was a complete stranger saying, "what did you say?"
One of the most intense experiences I've had is on a well made, very potent 15x salvia extract. Again the hallucinations seemed very real. I didn't know it it lasted minutes or seconds. I knew nothing of my normal reality I knew nothing of taking a drug. It was very much like a dream or rather a nightmare. As the nightmare neared the end I began to have a strong impression that I was outside my body and zooming out, coming back (to what I didn't know). I started seeing my room again. I gradually remembered my normal reality and that I'd taken salvia extract. I became fully aware of my surroundings but there was still intense fear. How can I put it? I was feeling de-personalised like only half of me was there and half was ripped out. The intensity of the hallucinations and the emotions was far beyond any other hallucinogen I'd tried before. I didn't think I'd return to normal. I was formulating the right sentence to I'd tell my boss I'm sorry I can't work for you any more. I've developed schizophrenia. Luckily it passed after around 20 minutes. The following 2 days I was left with an after shock of the fear.
An interesting phenomena I noticed with the hallucinations I got on anticholinergics was that I seemed to discover a method during the trip to test out if people or objects were real. The first bunch of hallucinations I was at a total loss. I interacted with them for ages until they evaporated in front of me. I really didn't like this at all. I tried blinking twice and I can't remember if it was an object or person first time but anyway it evaporated. Pretty soon I was blinking twice at regular intervals to see which people and objects would evaporate. It seemed to work. I spent less and less time tricked by fake people or objects. Then no more appeared. I do not know if this method seemed to work because for me because of my unconscious in relation to my childhood history with nightmares. As a child I believed I had the ability sometimes to wake myself from nightmares. This was because I'd had a number of nightmares where I'd had the sensation of becoming aware I was in one then blinking twice (or sometimes more if really bad) followed by waking up. Has anyone else tried this or really felt like they'd found a way to quickly test out the hallucinations that worked every time?