That case report actually has some pretty surprising data. I find it unlikely that the guy actually ingested 76mg of 5-meo-mipt. He would certainly have died or at least have had much worse symptoms than mentioned in the report. The chromatograms they supply agrees with their 60% methylone 38% 5-meo-mipt hypothesis but it is possible that the powder was not mixed homogenously. So, the patient could have had a much lower amount of 5-meo-mipt. Regardless, the supplier needs to be shot in the face.
"Thirty minutes later, he started to feel nausea and sick in the stomach, and visited one of his friends for help. In his friend's room, he shouted with agitation. He fell down on the floor, and he kicked around in a prone position aimlessly. He kept crying out that he felt very lonely, all is vanity, and added that he took a recreational drug “methylone” bought via internet. Soon an ambulance arrived, and medical technicians could not carry him because of his psychomotor excitement."
"His temperature was 37.8 °C, pulse 150 bpm, and blood pressure 144/81 mm Hg."
"One and half hours after risperidone treatment, his symptoms disappeared and he could communicate coherently."
"Two weeks after recovery from acute intoxication, he did not exhibit any residual symptoms including a depressive mood or euphoria. He, however, had no recollection of his experience during acute intoxication."
The pulse and blood pressure readings are way below what I'd expect at that dose. At 12-14mg, my BP, HR was 155/110, 130. The temperature increase is not that dramatic so serotonin syndrome is unlikely. Toxicity was probably more from the 5-meo-mipt.
Anyway 5-meo-mipt and methylone I think is a bad idea physiologically speaking because of the strong adrenergic effects of both drugs.
Visitor Q - 2cb on the comedown probably won’t do much due rapid receptor downregulation but should be safe.