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- Aug 4, 2010
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I just want to throw my hat in the ring regarding Loperamide (Immodium) usage in terms of mitigating withdrawal. Specifically, the title of the thread is concerned with the substitution of said drug for Methadone. Methadone is a very powerful Opioid, so in turn, you're going to need a lot of Loperamide to actually get well. The problem is that they are not equals in terms of dangers to your health. Loperamide is well documented to cause death in high dosages, if not by respiratory depression, by toxic cardiological effects. The more Loperamide you consume, the more likely you are to encounter a catastrophic reaction.
In my reckless days, I would drink my take-homes early and use Loperamide to make it to the end of the week. It was nothing for me to consume 200mg Loperamide in one shot. This is incredibly stupid and I'll admit that I noticed peculiarities in my heart beat. Whether it was psychosomatic, I couldn't say, but there is something that feels very "not right" about taking high dosages of Loperamide.
The only indication for its use that we can recommend in good faith would be a few times more than the standard recommended dosage. It is of course, an Opioid itself, so you're going to require a larger dose than a lay-person to control your gastrointestinal symptoms, but if you decide to escalate dosage, you are apparently taking your life into your own hands.
In my reckless days, I would drink my take-homes early and use Loperamide to make it to the end of the week. It was nothing for me to consume 200mg Loperamide in one shot. This is incredibly stupid and I'll admit that I noticed peculiarities in my heart beat. Whether it was psychosomatic, I couldn't say, but there is something that feels very "not right" about taking high dosages of Loperamide.
The only indication for its use that we can recommend in good faith would be a few times more than the standard recommended dosage. It is of course, an Opioid itself, so you're going to require a larger dose than a lay-person to control your gastrointestinal symptoms, but if you decide to escalate dosage, you are apparently taking your life into your own hands.