after my typical 6+ (usually six or longer) month breaks, 180 is a perfect amount for me to have a lovely evening! 80-100mg initial dose, then the rest @ peak to maintain the magic!
w/o some kind of tolerance, i can imagine 250mg being rather overwhelming/uncomfortable for alot of folks. i think, simply relative to my years of experience, i could handle it. the come-up would be MEGA intense, and the anxiety would surely produce some discomfort, but in comparison to your average twice-in-a-lifetime user - most PR cats could hold it down.
on the other hand you've got some heads that overdo it to the point where 250mg isn't a great roll, and judging by the way some members brag about their blatant abuse, perhaps not a very active dose @ all.
i'd definitely have no problem being a guinea pig for this bean that's for goddamned sure!! it's a shame - here in WI & IL (land of mints) imported dutch presses seem to be pretty uncommon, @ least to people i know. these things seem to pop up on the west coast far more often, namely CA. but then again, compare the population. i'm still waiting for one of those fuckin' bolts to fall into my lap!! (bolt=not an import, in case that confused anyone)