Only use loperamide if you have an opiate tolerance and are trying to get off of them..... (2-4 mgs is fine for someone with the shits).... but a non tolerant person taking 30 mgs and more.. etc.. is just reckless.
QFT, wreckless, dangerous and could be fatal. Non tolerant users should follow the instructions on the bottle to the letter as it works perfectly for the shits when they are followed. You need no more than a single pill.
A little fings to add, is that while Loperamide itself is non-recreational, if it passe the blood-brain-barrier,we can conclude it can potentialize other Opiod or CNS depressant compound and i know some ppl mixing DXM with Loperamide to counter the DXM diarhea (a frequent problems for some DXM users) so they should take caution about this mix as the Loperamide(supposedly) can potentiate the DXM too !
Loperamide defintely does not potentiate opioids and can raise your tolerance and make life miserable. It can be used via the instructions on the bottle to deal with diarrhea and that's it for the non tolerant, or it can be used by tolerant users in withdrawal to taper off opioids at the lowest dose necessary, though you should follow the instructions on the bottle and increase by 1-2 pills every FOUR hours (
YES it takes that long for loperamide to kick in and make a difference) until it works to lessen withdrawal symptoms, that is - by carefully taking THE LOWEST DOSE NECESSARY to lessen withdrawal symptoms. Much more than that and you'll be raising your tolerance and prolonging suffering. If it starts to remove most symptoms - but not all - you still shouldn't increase it anymore as those still present over loperamide will fade in a few days and then you should taper as fast as possible.
Following this I'm down to 8mg a day and plan on only taking 7mg today. This is from a starting point of 40mg-45mg (was too high of a dosage to begin with....)...... I'm proud of myself for sures!
Trying to use it as a magic pill to remove ALL symptoms as I've read some doing has pushed some people into stupid and unnecessarily and dangerously high doses which I'm sure definitely prolonged their suffering. Go read about some people at 200mg for a LONG ass time and how miserable it was for them to lessen that dosage, and keep in mind that I'm guessing the only people who should take 200mg are someone who is on like 10g of PURE IV DIAMORPHINE/HEROIN a day or that equivalent in other opioids.
Had a rather odd experience with Lope yesterday - combined inhibition of CYP2D6, 450 and p-GP allowed central activity. The 'high' has never been particularly pleasurable, always has that 'dirty' feel to it. Zero euphoria.
It did cause a resurgence of Hemifacial Spasms that I've been mostly free of for years. Demerol also did the same.
Given Meperidine's infamous toxicity, I am even more wary of Loperamide.
Anything sharing features with Pethidine is to be avoided, IMO.
Did you really have pinned pupils, because I believe that even in people non-naive to opioids (I.E. have some tolerance) you can still mistake the shitty peripheral effects for somewhat of an opioid 'feeling' even though there is never any high OR pleasantness. To anyone else, anyone chasing a feeling with loperamide is looking at either a seriously horrible time/life at best, and at worse ending up under a coroner's white sheet.
First time posting.. (Hydro/Oxy being my DOC) So, today was day 3 of WD's, I've been using on & off for about 4 years now & due to the fact that I no longer have health insurance & can't afford the habit, I'm trying to quit completely, despite my love for it. Lol.. Anyway, I took 10MG of Lope & most, if not all of my symptoms are now gone.. But now I'm worried about prolonging the WD process? Should I continue dosing with Lope for a couple days, or...? Help, please!
You should taper as rapidly as possible, if you can taper down to nothing in a week or yeah it may prolong your withdrawals a few days but they won't be near as horrible or unbearable as cold turkey and IMO still work it. I'm down to 8mg from 40mg though I have a feeling these 8mgs are gonna suck tapering 1mg off at a time, but as I said it is still doable and so lightweight/easy that it prevents me from seeking out a REAL (read fully CNS active) opioid. I don't know how sucky it's really going to be though as I've not gotten this low before, but it seems for most opioids the last steps suck a lot, but going from 40->8mg has really been pretty painless, so we'll see.
(this is
not in reply to the last quoted post FYI):
If you disagree and think you can still get high on loperamide please see "The Shrine" for a bluelighter who died from loperamide or the mothers post in this thread who lost a son who was trying to get high on this drug. If you still think you can get high please keep it to yourself or realize you're a moron. 
