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Dresden's Chemical Fluff Thread (Name-A-Molecule)

Most Self Reinforcing Drug I Can Think Of

1-phenyl-1-carbomethoxy-1-(morpholine-3-yl)-methane.png


MORPHO-MPH
1-phenyl-1-carbomethoxy-1-(morpholine-3-yl)-methane

1-phenyl-1-carbomethoxy-2-(morpholine-4-yl)propane.png


MORPHO_AMP
1-phenyl-1-carbomethoxy-2-(morpholine-4-yl)propane

With a dash of R-(C=O)-O-CH3.
 
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6-hydroxy-3-(methanone-1-yl)-indole.png


Commercially available.
6-hydroxy-3-(methanone-1-yl)-indole

1-(6-methoxyindol-3-yl)-2-dimethylaminoethane.png


DMT-6
1-(6-methoxyindol-3-yl)-2-dimethylaminoethane
 
1-(5,6-dichloroindole-3-yl)-2-dimethylaminoethane.png


DMT-4,5-Cl,Cl
1-(5,6-dichloroindole-3-yl)-2-dimethylaminoethane

from the commercially available

5,6-dichloro-3-(methanone-1-yl)-indole.png

5,6-dichloro-3-(methanone-1-yl)-indole
 
The Anderson Reaction:

1-phenyl-1-hydroxy-2-methylaminopropane.png


Ephedrine
1-phenyl-1-hydroxy-2-methylaminopropane

1-phenyl-1-chloro-2-methylaminopropane.png

1-phenyl-1-chloro-2-methylaminopropane

1-phenyl-1-cyano-2-methylaminopropane.png

1-phenyl-1-cyano-2-methylaminopropane

Br2 / FeBr3

1-(4-bromophenyl)-1-cyano-2-methylaminopropane.png

1-(4-bromophenyl)-1-cyano-2-methylaminopropane

1-(4-bromophenyl)-1-carboxy-2-methylaminopropane.png

1-(4-bromophenyl)-1-carboxy-2-methylaminopropane

1-(4-bromophenyl)-1-carbmethoxy-2-methylaminopropane.png


BROMO_L.O.V.E.
1-(4-bromophenyl)-1-carbmethoxy-2-methylaminopropane

In 5 Steps.
 
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1-(3,4-methylenedioxyphenyl)-1-acetyl-2-(methylamino)propane.png


TRIS
1-(3,4-methylenedioxyphenyl)-1-acetyl-2-(methylamino)propane

Say goodbye to anhedonia and depression!

1-phenyl-1-acetyl-2-(methylamino)propane.png


TETRAKIS
1-phenyl-1-acetyl-2-(methylamino)propane

What Do We Want? Euphoria!
Where Do We Find It? Various White Powders.

His ADHD Is Not Being Properly Treated.
TETRAKIS Can Help. Ask Your Doctor If TETRAKIS Is Right For You.
 
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2-oxo-pent-3-ene.png

2-oxo-pent-3-ene

Next, Br2 liquid brominates the double bond on each of its two carbons

2-oxo-3,4-dibromopentane.png

2-oxo-3,4-dibromopentane

Then, just add benzene or toluene or 1,3-benzodioxole plus Br2 and FeBr3.

Walla, 3 Productos.
I Am Not Sure What The Solvent Should Be. I'm thinking either ethyl alcohol or tetrahydrofuran.
 
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2-(1-carbomethoxy-2-aminopropyl)naphthalene.png


ALEVIATE
2-(1-carbomethoxy-2-aminopropyl)naphthalene

1-phenyl-1-carboethoxy-2-ethylaminopropane.png


MISS_PACMAN
1-phenyl-1-carboethoxy-2-ethylaminopropane

1-(2-naphthyl)-2-ethylaminopropane.png


DEPECHE_MODE (French for, 'fast fashion')
1-(2-naphthyl)-2-ethylaminopropane
 
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(1S,2S)-1-phenyl-1-carbomethoxy-2-methylaminopropane.png


DOUBLE_DEXTER_FINN_AGAIN

(1S,2S)-1-phenyl-1-carbomethoxy-2-methylaminopropane

from
(1R,2S)-1-phenyl-1-hydroxy-2-methylaminopropane.png


(1R,2S)-1-phenyl-1-hydroxy-2-methylaminopropane



Actually, I think the hydroxyl group may switch around the stereochemistry of the one spot after it undergoes a substitution reaction. I was never very good with the whole Khan Ingold Prelog (R,S) nomenclature.

Anyway, if that is the case, then this is the correct precursor:

(1S,2S)-1-phenyl-1-hydroxy-2-methylaminopropane.png


(1S,2S)-1-phenyl-1-hydroxy-2-methylaminopropane

BUT it undergoes 2 substitution reactions, so the former would be correct.

Errg, Forget Stereochemistry! All I Know Is That Ephedrine Comes In 4 Stereochemicals, And One Of Them Is Correct. Specifically, It Has A (2S).
 
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benzophenone.png


benzophenone

plus nitroethane, etc. -->

1,1-diphenyl-2-aminopropane.png


BISPHENYLAMP
1,1-diphenyl-2aminopropane

oxybenzone.png


oxybenzone

-->

1-(2,4-dimethoxyphenyl)-1-phenyl-2-aminopropane.png


MIXEDBISPHENYLAMP
1-(2,4-dimethoxyphenyl)-1-phenyl-2-aminopropane
 
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1-(1,3-dioxoindan-5-yl)-2-methylaminopropane.png


RODENTICIDE
1-(1,3-dioxoindan-5-yl)-2-methylaminopropane

This one doesn't look safe or anything. Proceed with caution, if at all.

1-(2-oxoindan-5-yl)-2-methylaminopropane.png


DANIEL
1-(2-oxoindan-5-yl)-2-methylaminopropane

1-(2-oxo-3-oxaindan-5-yl)-2-methylaminopropane.png


THE_LION'S_DEN
1-(2-oxo-3-oxaindan-5-yl)-2-methylaminopropane

May be metabolized into something gbl like.
Me So Horny! Lol.
 
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1-(1,3-dioxoindan-5-yl)-2-(1-pyrrolidinyl)-1-oxopropane.png


BRAD_PITT
1-(1,3-dioxoindan-5-yl)-2-(1-pyrrolidinyl)-1-oxopropane

1-(2-oxoindan-5-yl)-2-(1-pyrrolidinyl)-1-oxopropane.png


JOHNNY_DEPP
1-(2-oxoindan-5-yl)-2-(1-pyrrolidinyl)-1-oxopropane

New Car Smell.
 
benzene.png


benzene

Cl-(C=O)-CH2-(C=O)-Cl

1,3-dichloroacyl-maleic acid

AlCl3(s)

1,3-dioxoindan.png


1,3-dioxoindan

Protect oxo's with ethylene glycol, then react with Cl-(C=O)CH2CH3 and AlCl3. Then Br2, then deprotect with H+.

1-(1,3-dioxoindan-5-yl)-1-oxo-2-bromopropane.png


1-(1,3-dioxoindan-5-yl)-1-oxo-2-bromopropane

Pyrrolidine.png


pyrrolidine

1-(1,3-dioxo-indan-5-yl)-1-oxo-2-(1-pyrrolidinyl)-propane.png


1-(1,3-dioxo-indan-5-yl)-1-oxo-2-(1-pyrrolidinyl)-propane

You might have to fiddle around with the protecting groups, but this is the gist of it.
 
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1-(indole-3-yl)-1-carbomethoxy-2-aminopropane.png


GEETERED
1-(indole-3-yl)-1-carbomethoxy-2-aminopropane

1-(indole-3-yl)-1-carbomethoxy-2-dimethylaminoethane.png


SKEETERED
1-(indole-3-yl)-1-carbomethoxy-2-dimethylaminoethane
 
acetylene.png


acetylene

Diels Alder

Benzene.png


benzene

1-chloro-1-oxopropane.png


1-chloro-1-oxopropane

AlCl3

Friedel Crafts

1-phenyl-1-oxopropane.png


1-phenyl-1-oxopropane

Br2

1-phenyl-2-bromo-1-oxopropane.png


1-phenyl-2-bromo-1-oxopropane

CH3CH2NH2

1-phenyl-1-oxo-2-ethylaminopropane.png


1-phenyl-1-oxo-2-ethylaminopropane

NaBH4

1-phenyl-1-hydroxy-2-ethylaminopropane.png


1-phenyl-1-hydroxy-2-ethylaminopropane

Cl-(C=O)-Cl

1-phenyl-1-chloro-2-ethylaminopropane.png


1-phenyl-1-chloro-2-ethylaminopropane

KCN

1-phenyl-1-cyano-2-ethylaminopropane.png


1-phenyl-1-cyano-2-ethylaminopropane

H3O+

1-phenyl-1-carboxy-2-ethylaminopropane.png


1-phenyl-1-carboxy-2-ethylaminopropane

1-phenyl-1-carbomethoxy-2-ethylaminopropane.png


FANCY_FEAST
1-phenyl-1-carbomethoxy-2-ethylaminopropane

Bon apetit!
 
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1-(4-methylphenyl)-1-carbomethoxy-2-ethylaminopropane.png


BILLY
1-(4-methylphenyl)-1-carbomethoxy-2-ethylaminopropane

Same as above, except for toluene instead of benzene.
 
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