I think if you shoot it all bets are off. I have had a few side effects I am not pleased with. Some of the way your body releases meth is through the pores. When the pores struggle to open and expel the poison they can get infected a bit. I have had a few of those on my back. I read every book about meth I can find so I know what the hell is going on when something arises.
I take back what I said earlier about not knowing anyone that looks that bad as those mug shots they post. Street prostitutes look like that, a lot of 'em. Being homeless, addicted, and prostituting takes away everything a female human being has. The only way you can sink any lower is being on death row. And the two are equatable in my mind: YOU ARE DYING. When you are addicted, homeless, and a prostitute you are busy killing yourself. When you are on death row society has deemed you acceptable for extermination i.e. to be killed.
Those girls that ended up on the street, I wonder where they came from. Does anybody love them? What happened? Frontline I think it was, profiled three women that were murdered in Las Vegas and their bodies dumped in the same spot. They all had lives much like most of us, boyfriends, husbands, children, parents. The pictures shown of these woman at an earlier time, they looked like most of us do. Regular people. They still had hope in their eyes. Then they got hooked. Then they ended up on the streets behind their habits. Then, tortured, raped, and murdered, the final insult.
Sorry, got off track. I do not think that method of administration matters much with meth. It is poison, and what goes in must come out. I do think that me smoking a $20 bag (two tenths of a gram) over two or three days (and sleeping 10-12 hours in between) is a bit different than fixing up the whole $20 at one time and slamming it. The rush must be orgasmic. But because the amount used is so much larger the side effects must be more pronounced e.g. the picking of the skin, the paranoia, not eating or sleeping, weight loss, etc.