LSD is not actually nature-made, but many psychedeics are, DMT is vey common in nature, and even produced naturally in the human brain whie sleeping. LSA, Psilocybin, Mescaline, and Ibogaine are also nature-made. All of there are illegal in the US, but the plants that produce them are usually not. But even illegal items can be widely available commercially. Coca leaf tea and dried opium poppy pods are good examples. In my own expierence, law enforecement of drugs exists to collect money for the government, and is frequently ripe with corruption. My personal opinion is that noone should use any drug without first researching it fully. I have found that recreational drug use can very easily be resposible drug use, if people just use common sense, ie, not taking larger doses than one can handle. and not causing problems for others (this is key) Psychedelics do have medicinal value, as they are serotonin receptor agonists, they can be used to treat a number of mental conditions.