I used to have lengthy, multiple, involved email questions and arguments with Dr. Dave until we got sick of each other. Dave Nichols is can be a cranky old professor when he wants, but he seemed pretty nice on computer anyway.
What makes you assume I am looking for a 5-HT2a agonist at all or that I said DOAM was one? DOAM may not be a 5-HT2a agonist, but its effects are described by Shulgin in "PiHKAL" (Dr. Dave derisively called "PiHKAL" devotees, "Shulgin-worshippers") as something to the effect of "This developed into a pleasant high that in no way interefered with my day's activities" and "I was quite gay and voluble at lunch" and "There was a strange tenseness during driving." All that at only 10 mg; what about 100 mg?
PM me and send me 100 mg DOAM and I'll tell you. It's got to be better than 100 mg doses of TMA-2 and TMA-6 were for me. It could even rival MDMA and be much more psychedelic as well. As for the lipophilicity of the added 4-(n)-pentyl group, there can be no argument against its extreme affinity for the brain's phosphatidyl nucleotidlyl triacylglycerides and proton pumps (all imaginary biological pseudoscientific adjectives to explain the unexplainable "Meaning of Life)."
I am not interested in the pure biological systems upholding the metabolism and effects of drugs, but rather the organic chemical structure of the drug itself, along with its density, color, refractive index, odor and taste. If you think computerized model, even done with supercomputers, can approximate what kind of molecular interactions a drug will have with target and peripheral proteins as it makes its way through the human body, then you should work for IBM.
According to the Hindus, the meaning of life is an Indian word called LILA that, roughly translated, means 'God's play'--namely, the lives of you and me are the soap opera of God and the demi-Gods and host of angels who support him.
Speaking of far out religions, I wonder how Bob Dobbs' church is doing in 2004 or if it is still doing? The mastercreator behind Church of Bob Dobbs always reminded me of the Hive's Strike in his mindset. One of those books even described the chemical composition of a fictitious, ideal planet; its air consisted of 10% percoset (oxycodone) and 90% MDMA. My perfect planet would have 15% THC, 25% Zyprexa, 25% pure meth, 5% Valium, 5% cocaine, 15% MDMA and 10% hydrocodone. Ananda!!!
I know White Fluff reportedly inadvertently, I presume, killed himself in a massive drug overdose of one kind or another. I heard that last factoid 2nd hand at the hive, but it's probably true because I haven't seen any 300 microgram family blotter coming down from Tennessee in several years. BTW Billy / "Freeze" from Tennessee who was friends with Dawn if you or one of your friends sees this message, then PM me for sure, and we will hang out.
I had some "Mad Hatter" from up in the Appalachian foothills and mountains once, but while very strong it was no match for the clean, sunlight bathed glow of "White Fluff."
Chinacat, a member at certain other message boards and maybe this one too, ranked "White Fluff" as the highest grade of about 3 or 4 grades of commercial acid and family acid which she had trafficked for years at the Grateful Dead shows while in her mind being protected by God by not being ever detained or arrested by the authorities for the technically felonious LSD distribution.
As for the current US LSD drought, never fear, the Dutch scientists got good enough to synth LSD all by themselves and supply the world with billions of MDMA/MDA/MDE/METH pills that it requires seemingly every weekend. Unfortunately, the Hollander that I talked too wanted 500 USD per sheet. Supply, demand and the vagaries of commondities on the world market is mind boggling, but I never paid more for 175 USD for family vials or commercial white blotter either.
Alternatives to LSD:
Luckily, 4-OH-MIPT can be dissolved in ethyl alcohol in sweet breath bottles and ingested 35 to 40 mg at a time (do you math; remember mass, m (in kg), equals volume (in m3) times density (in kg/m3, for example)). The 4-OH's react with each other to form purple dimerized peroxides which color the solution black to dark purple. Side effects include a mild high, few visuals, moderate duration (from 15 min to kick in to 5 hours to wear off or at least significantly subside in intensity), some euphoria, some music enhancement, increase in friendliness, mild headache, increased color appreciation and facial flushing.
fastandbulbous,
If you are a 5-HT2A agonist purist scientists poppin' Guiness, then I would suggest devoting your life to lsd manufacture for a while. Only the people with pure karma withstand the initiatory "thumbprint," while the actual chemists often say a prayer to bless the recipients of each of the users of their new batch of crystal, and get high by osmosis.
Personally, I like the way the word 'crystal' can refer to pure lsd or pure methamphetamine ("ice"), even though they are as different from each other as night and day, literally. I like to think of shards coming from the frozen tundra of Alaska and northern Canada where the Northern Lights (an obvious double reference there) appear repeatedly and where pot is a misdemeanor at most, while LSD is a dirty, sweaty, insane Australian / South Pole aboriginal type. These two crystals are the primordial serotonin and the primordial dopamine crystal vibrations and blueprint for consciousness in what would otherwise be a large group of non-sentient, silly simians (note the alliteration or was that consonance?).
Anyway, one time when I was locked up in a state run mental institution this middle aged Jewish man from NY told me that I looked like the picture of Roget of Roget's Thesaurus fame. And my vocabulary does tend to border on the ponderous side--I used to memorize extensive word lists; now I read medical dictionaries. We don't look alike, as it turns out, but then my sister's father-in-law told me I look like Abraham Lincoln, which I kind of do, at her June wedding. He looks like Thomas Jefferson, though; alas, if only Jefferson in all his knowledge and wisdom had added an amendment to the Constitiution with the Bill of Rights (the first 10 amendments of the Constitution) prohibiting the US government's banning of any food or drug.
This Christmas someone needs to come up with a cannabis effect producing amphetamine and then a nicotinic amphetamine as well. I wouldn't mind doing a phat rail of crushed up shards, too.
Important Factoid:
Did you know that under the federal sentencing guide lines you can have up to 5 grams of pure meth before getting the automatic 5 years with only 15% of the time eligible for parole?
"I'm down here on my knees, I'm saying please, pleassee."--Edward KaSpel of the Tear Garden (also sings the lyric, "for the pill, the precious pill").
Finally, and I apologize for rambling, but as for 1-(2,5-dimethoxyphenyl)-2-methylaminopropan-1-one hydrochloride, that shit is crap and should not be purchased. I finally chose to flush my last 750 mg of it down the toilet; that's all it was worth. Icould have PM'ed one of you and sold it for cheap, but I didn't. Drug dealing, even with RCs, is a sketchy business which I avoid. Cheers.