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The Big & Dandy Methoxetamine Thread - The 3rd Dose

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Whats good antidepressant bumb ? I've got a 300mg sample and just wanted to test out its antidepressant nature tomorrow but don't want to trip as I have work.

Also I want the majority for this weekend as me and two mates are planning on tripping hard on this. We have no ket tolerance as we have only done it a few times so would 300mg - antidepressant bumb be enough for 3 of us to have a fun time ?
 
With no tolerance, 300mg between three of you is a LOT
Be careful, this is powerful stuff.
 
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I just got a gram of supposed methoxetamine, 10mg made me feel very heavy, trippy and drunk. Just bumped 25mg and feeling the psychdelic gravity making mashed potatoes of my muscles and brain. This is a serious tool and I hope we get a grip on how to work with it.
 
psychoblast said:
I'd like to start a board or chat or some kind of online connection for others who, like me, like MXE, so we can share and compare experiences and insights, as well as stay up to date on the latest medical issues (since the biological effects of prolonged use of this is not known.

I like to think people are different and what works for some may not work for all. MXE is not some awesome party feel good drug, but it works for me. It is the best thing I've found at managing my anxiety and stress and issues and conditions. Might a pharmaceutical company get involved in this and make it legit?

~psychoblast~
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I'm totallly right there with you on that notion. I looked into MXE because of its relationship to opiates and ketamine. I am taking currently 60mg a day of morphine for chronic pain and deal with depression going on ten years. I read John Lily's book about ketamine and how it allowed him to keep pain away for extended periods, then lately how ketamine has been shown to have long lasting anti depressant effects. So MXE looks to be a promising substance for sure because it combines opiate and ketamine like effects. This won't work as a recreational drug it would be instant car crash if you try to drive is my impression less than 30 minutes after ingesting 25mg.
 
^^^ And the ability to drive a car is what qualifies a drug as being recreational?
 
People need to remember what this stuff is. Its worrying to see heavy use of this compound being reported when almost nothing is known about it. We already know regular use of dissociatives can have detrimental effects on the body and mind. There wasn't much for me to gain from it all and it looked as if the path would not lead anywhere good, therefore it had to come to an end. Safety should be #1 priority.
 
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ashxcore said:
I have to wonder how many of you who are prattling on about MXE are very familiar with dissociatives? I am not trying to negate any experiences at all, but it seems like for many, MXE could have been a first foray into NMDA antagonism. I guess I cannot wrap my head around why I have had wildly different experiences than many of you with these glowing reports. Perhaps it is just the way my brain is wired...
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My dissociative experience includes numerous experiences with ketamine, DXM, 4-MeO-PCP, nitrous, 3-MeO-PCP, and a few 3-ho-PCP experiences. I've easily had the highest rate of both profound and glowing experiences with methoxetamine -- understood as a ratio of experiences I consider profound and/or glowing over all experiences. Compared to ketamine on its own I feel methoxetamine is superior, though I've never "k-holed," despite numerous attempts. I'm also in a minority in that I find DXM on its own better than ketamine on its own (though ketamine in combination with a 5HT psychedelic I find vastly superior to DXM with a 5HT psychedelic). The mania of methoxetamine is heavenly, and ketamine doesn't have the quality for me.

I agree, though, that the relative paucity of access to other dissociatives compared to access to methoxetamine is probably a factor in all the positive reports. There's simply more enthusiasm and propensity to report when you suddenly have access to a new class of drug. Though it's impossible to say if all these people had access to numerous other dissociatives whether they would still prefer methoxetamine or not. I assume it has a lot to do with the vast numbers of UK people (who also seem to make up most of the new bluelight members) introduced to current methoxetamine vendors through previous mephedrone purchases.
 
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You tell me, Going off your wording :) But heavens no, I certainly try to avoid vehicles in all shapes and forms when under the influence of dissociative anesthetics. But maybe that's just me.

Cheers
 
I read someone saying something about eating etizolam and not feeling the mxe, and I drank like 3 beers tonight before I did an I.M. and I don't really feel it as much at all, the whole mental thing is gone.

something with the GABA receptors affects the NMDA receptors or something?
 
I seriously question any individuals ability to safely use MXE as an antidepressant when it pretty clearly causes mania (technically opposite of depression) which is totally not a good place to be outside of a "high".

Just felt I should say that in case others haven't.
 
Funny thing is i've been enthousiastic about mxe ever since I heard about it and havnt had a negative experience on it yet, but when I let my friends try it, generally their first time is just 'weird' (so was mine btw), I think it's because they don't really know what to expect.
Afterwards they seem to enjoy it more every time they try :)
The mxe situation at the moment is just optimal I guess, this is the kind of 'new' drug a lot of people have been waiting for.
 
Yeah it really is great. But I think it should remain JUST a "great drug". Not some "new wave" or revolution in pharmacology and spirituality. That's just not a useful mindset IMO, totally delusional.
 
So a little more research and I have decided I won't be touching my order, personally. Olney's Lesions. Sounds like tons of fun.
 
Weren't Olney's lesions under some pretty heavy speculation for their legitimacy? Not questioning your caution, just think its worth looking into.
 
invert said:
Yeah, forgive the idiosyncratic terminology... I call auditory hallucinations (particularly when experienced in relative silence) closed ear audials by analogy with closed eye visuals; I don't think anyone else does... :)

I'm not sure whether I'd say my CEAs on DiPT (and some other psychs) are perceived as inside or outside my head. They tend to be attentionally modulated: they get louder and more intricate the more I attend to them, and I tend to notice them only in silence. But it's not like just imagining music: it's not out-there, directionally, but it's out-there in the sense that it is (aside from attentional modulation of intensity) not under my control. It feels like hearing externally produced music in pretty much every sense other than in its having a location outside my head.

[I've described my experiences of CEAs on DiPT at length elsewhere, if you're interested, in a trip report.]

I find, at least at the dosages that I've taken methoxetamine at so far, that its sensory effects are somewhat attentionally modulated too. Most notably the kinaesthetic hallucinations (sense of being bodily moved, like on a rollercoaster, while objectively lying still... closed body kinaeals, if you will ;)), which have been the most dominant effects I've experienced so far; but also the CEVs.

ETA: What route of administration are those dosages for? I find sublingual seems twice as intense at peak (and twice as fast to reach peak) as insufflated.
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Ahhh, this clears it up, thanks. Yes, it was very much out of my control. I couldn't consciously manipulate the music, it seemed to play out of it's own accord. I'm going to read that trip report in a minute as this has inspired an interest in this topic for me.

Most of my doses have been insufflated, although I think (I took the stuff five nights in a row so I might be getting muddled and can't be sure) that on this particular night in question my initial dose was sublingual, with the follow up dose insufflated an hour later. I definately felt a difference in the effects. It seemed more intense, but also clearer in some way I find hard to describe. I'm about 70% sure that this was on that night, but don't quote me.

ashxcore, I myself had only a little dissociative experience before MXE, which consists of a few DXM trips. I get the feeling I'm going to experience this drug class alot more...
 
nearjat said:
Yeah it really is great. But I think it should remain JUST a "great drug". Not some "new wave" or revolution in pharmacology and spirituality. That's just not a useful mindset IMO, totally delusional.
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You have a point. We could end up with a bunch of Tim learys running around, and consequently all these drugs being widely condemed, as lsd and similar psychs were in the 60's.

on the other hand,

It's hard to keep this stuff to yourself whether it is brain damage, a spiritual/pharamacological revolution, or whatever. :)

Try not ending up in the padded cell folks.
 
Surprisingly, I much prefer snorting MXE to sublingual dosing.

I find the effects of both to be similar, with sublingual leaving me with a distinct "vibration" feeling. My problem with sublingual is that my mouth salivates far too rapidly, making holding the MXE in place for more than a few minutes a massive pain. My tongue also feels overly numb for quite a long time afterwards.
Not to mention the horrible taste...

Whereas, with insufflation, it goes up with no pain and just takes a quick snort. The only issue is the backdrop, which is easy to manage if you have a drink nearby.

I guess that I go against the grain here. I would like to try other methods of administration, but I'm not nearly adventurous enough.

Anyways, I'm really missing MXE, but I'm forcing myself to avoid it due to all the theories of neurotoxicity...I really wish there was a way to disprove it, but alas, it'd take years of testing.
 
2charlyecho said:
Try not ending up in the padded cell folks.
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When you do this five nights in a row, and I know others have done this for longer, and with larger doses than myself, I Found that I didn't quite feel myself. It is prudent to take alot of caution with this.

In resonse to oSpherical, I find insuffalting to be sufficient although aublingual is more intense, if more of a pain in the arse.

You're not the only one who sees this as generally the most efficient way of taking MXE in terms of preperation time and comfort.
 
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