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The Big & Dandy MDAI Thread

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Tramadol is a serotonin releaser and not a SSRI apperantly[1].

I was actually referring to tramadol's SNRI effects when i mentioned it+mdpv+mdai. Did not know it had such substantial effects on serotonergic systems. Some days i learn more on bluelight than i do in school.
 
Tramadol is a serotonin releaser and not a SSRI apperantly[1].

The compilation of studies that you reference actually tells a complex and ambiguous story, shedding doubt on tramadol's efficacy as an SRA in vivo. Unfortunately, this story is a bit beyond my levels of knowledge and comprehension.

ebola
 
What about adding Butylone for Dopamine and NE?

I don't mean to upset anyone by asking questions about combinations in this thread but I can't help to wonder the same thing.

So, some experiences with this combo? :eek:

(didn't find any in the thread but I just skimmed through it)
 
Does MDAI cause you to get hanging eyelids like MDMA can do?
Because I thought this was a treat of released serotonin...
 
Does MDAI cause you to get hanging eyelids like MDMA can do?
Because I thought this was a treat of released serotonin...

I'm very sensitive to MDMA, methylone etc in regards of making me feel "like shit" (hanging eyelids, and just looking terrible) MDAI on its own wasnt very bad tough.
 
130 mg MDAI didnt make my eyelids hang. Looked almost completely sober. Then again the experience is nowhere near the mdma experience to me. Was pretty damn comfortable though.
 
There are heaps if combo experiences we've clocked a few up . Next on our list 160mg mdai , 100 butylone and 5mg mdpv . Sadly my tianeptine shipment didn't arrive I would have loved to have done some more tianeptine an mdai experiments
 
Our reason for butylone is purely selfish. Last time I had m1 I had all encompassing paranoia which lasted for weeks. So I have absolutely no desire to actually even repeat a test with m1 so b1 it is .
 
Our reason for butylone is purely selfish. Last time I had m1 I had all encompassing paranoia which lasted for weeks. So I have absolutely no desire to actually even repeat a test with m1 so b1 it is .

I assume you've tried butylone alone and not had such a problem.... Usually B1 is said to have more negative aspects than methylone.

Maybe i just didn't react well to MDPV, but i can't see anything good from coming out of mixing a jittery nasty stimulant like that with a beautiful drug like MDAI - i'd love to mix it with buphedrone though...
 
Yes I do have experience with it on it's own . No problems lol . Mixing it with buphedrone we have had a Lot of success . Given it's so hard to get we've opted for mdpv.

See my report earlier in the thread re buphedrone :) lovely clean stim

At this point some friends who have tried the above named combo in a club setting have all had positive things to say. The mdai seems to take the edge off the butylone.
 
(warning: some redundancy with a prior post of mine in this thread)

From such reports, it will be interesting to see if reliable patterns emerge for which types of stimulants pair best with MDAI (sorry Jamshyd ;)), or if it is simply idiosyncratic. If it is indeed idiosyncratic, which patterns fall out according to which stimulants one prefers or according to another, less easily discernible pattern? Will a large proportion of those who respond poorly to mdpv or butylone taken on their own find either substance particularly good (rated against other potential stims for combination) in combination with MDAI?

I hypothesize that for those who prefer vastly MDMA/MDA's effects-profile, DA releasers will be superior to DARIs in such combos (but more neurotoxic). From here, which stimulant will perform better might be a matter of idiosyncratic preference. Those preferring a high degree of stimulation in their rolls (they might find speed + mdma to approach their ideal) might prefer a heavily NA/DA selective agent with strong NA activity in combination with MDAI, eg d-amphetamine, combined with a small to moderate dose of MDAI. Those preferring comparatively more 5ht efflux (perhaps wishing that MDMA were less stimulating, or even preferring MDEA), might want to choose a comparatively more serotonergic stimulant (eg, methylone), perhaps paired with a moderate to large dose of MDAI.

ebola
 
A little besides the point but, who else thinks this is a "cute" molecule? I guess it kinda reminds me of a mouse or something of that sort.

Anyway, carry on...
 
i do! (true of most 2-AI derivatives).

130 mg MDAI didnt make my eyelids hang. Looked almost completely sober.

obviously dilated pupils? It's things that release 5ht or agonize it strongly (at 2a!) that blow up my pupils quite readily, not classical stimulants.

i think that a key factor undergirding the 'munted', eyes rolling back high is concurrent release of all 3 monoamines.

ebola
 
(warning: some redundancy with a prior post of mine in this thread)

From such reports, it will be interesting to see if reliable patterns emerge for which types of stimulants pair best with MDAI (sorry Jamshyd ;)), or if it is simply idiosyncratic. If it is indeed idiosyncratic, which patterns fall out according to which stimulants one prefers or according to another, less easily discernible pattern? Will a large proportion of those who respond poorly to mdpv or butylone taken on their own find either substance particularly good (rated against other potential stims for combination) in combination with MDAI?

I hypothesize that for those who prefer vastly MDMA/MDA's effects-profile, DA releasers will be superior to DARIs in such combos (but more neurotoxic). From here, which stimulant will perform better might be a matter of idiosyncratic preference. Those preferring a high degree of stimulation in their rolls (they might find speed + mdma to approach their ideal) might prefer a heavily NA/DA selective agent with strong NA activity in combination with MDAI, eg d-amphetamine, combined with a small to moderate dose of MDAI. Those preferring comparatively more 5ht efflux (perhaps wishing that MDMA were less stimulating, or even preferring MDEA), might want to choose a comparatively more serotonergic stimulant (eg, methylone), perhaps paired with a moderate to large dose of MDAI.

ebola

I want to try a few more myself. I've gone the MDAI+M1 route, and it was extremely enjoyable, though not the most efficient combo, as in i couldn't get enough into just one gel capsule... Tried amphetamine salts+MDAI+M1, and that was slightly more efficient, but still required a lot of material, though I didn't take that much amphetamine ~10mg. I really like the idea of toying with the ratios to personalize your experience. This type of thing may well be the future of well informed drug use. Cutting edge stuff really, and the therapeutic potential may even rival or surpass that of MDMA due to the variable stimulation...

A little besides the point but, who else thinks this is a "cute" molecule? I guess it kinda reminds me of a mouse or something of that sort.

Anyway, carry on...

Word, i totally dig the symmetry.
 
Any major dude if you can acquire some tianeptine you may be able to decrease the amount of material required ;)
 
Anyone tried this with 5-meo-dalt? I hear the combination works better than the two on they're own?
 
i do! (true of most 2-AI derivatives).



obviously dilated pupils? It's things that release 5ht or agonize it strongly (at 2a!) that blow up my pupils quite readily, not classical stimulants.

i think that a key factor undergirding the 'munted', eyes rolling back high is concurrent release of all 3 monoamines.

ebola

Well, pupils somewhat dilated. But the degree which my pupils dilate reflects how strong an experience Im having. If my trip isnt very strong, my pupils are only a little dilated, if Im tripping like fuck I have huge pupils. But that night I couldve passed as just plain drunk.

Ive only tried 40 and 130 mg of this stuff on two occasions and so far I think its very subtle. But thats what makes this stuff kinda cool :)
 
Trials begin tonight; 150mg oral.

I'm excited :D
 
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anyone combined MDAI with MPH? I was wondering because of the speculative lack of neurotoxicity when combined with a DARI vs. some neurotoxicity when used in combination with a DA releaser (i.e. d-amph & salts etc.)
 
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