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The Big & Dandy Methoxetamine Thread - Part 13: Don't you know? MXE comes from MXE-co

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Cheap self-help for MXE overuse

The easiest way I can think of to control one's rate of use of a problem drug they're not physically addicted to is to simply rent the smallest/cheapest bank safe-deposit box you can find reasonably far away and keep it stored off site. A cheap one is around $35 per year. If you're a frequent user, think about how much money in MXE it would save you if you had to leave your place and go to a bank that's typically closed weekends to get MXE.

The typical cycle that leads to unplanned dosing is as many people have noted: "Why not use MXE now? ... Fine, I'll do it tonight, but try harder to skip it tomorrow." Then tomorrow comes and circumstances haven't meaningfully changed so ... . Safe deposit box storage still allows you to decide to do it "tonight," but assuming you only take one night's pre-measured supply (concealed in a common container that looks like it belongs there), it literally forces you to try harder "tomorrow" -- or simply denies you access during the hours/days the bank is closed. It changes the circumstances in a way most frequent users find it very difficult to do using sheer will power by making the most frequently-cited method of taking a break, "running out," a far more frequent occurrence. This sort of forced moderation of course also has the benefit of radically improving the experience.
 
Goddamned MXE tolerance made me waste 4grams of Ketamine this weekend.

Still haven't ordered MXE in a month. Doing my best to continue. It's hard when it's just about my DOC next to weed.
 
Goddamned MXE tolerance made me waste 4grams of Ketamine this weekend.

Still haven't ordered MXE in a month. Doing my best to continue. It's hard when it's just about my DOC next to weed.
Wow how much mxe are you talking? 3 months of daily use and I still was doing the exact same dose with the same effects .. Zero tolerance.
 
MXE's afterglow with a benzo is the pierfect high. so brilliant. High def beautiful vision/perception, so much clean energy. MXe alone is a little "tight" or "tense" but with benzo, god its just perfect.

The way I would describe it is that the benzo eliminates the body load, and its purely a visual/energetic experience

The only problem is benzos are physically addicitive so this combo (even though it turns MXE into the perfect high) turns it into a physically addicitive high, which kinda ruins one of the main benefits of MXE which is that it isn't physically addictive

Well put! For me it more smooths out the mindset. It takes away a bit of the anxiety and paranoia that I can get from MXE alone. Makes it easier for me to get out of the house on it. I also find that it doesn't diminish the mental effects if you keep the etizolam dose low. The 2 downsides for me are having a harder time recall the experience later and a way larger decrease in coordination. I tend to play bumper cars with the walls a lot with this combo
 
Wow how much mxe are you talking? 3 months of daily use and I still was doing the exact same dose with the same effects .. Zero tolerance.

If you read the rest of his posts in this thread, it sounds like he was taking at least several grams a week for quite some time.

I could never imagine keeping even 5g of this stuff around and not being tempted to use it all the time, much less 50+g constantly.
 
Well put! For me it more smooths out the mindset. It takes away a bit of the anxiety and paranoia that I can get from MXE alone. Makes it easier for me to get out of the house on it. I also find that it doesn't diminish the mental effects if you keep the etizolam dose low. The 2 downsides for me are having a harder time recall the experience later and a way larger decrease in coordination. I tend to play bumper cars with the walls a lot with this combo

i had much, much better results using freshly prepared kava kava (made from pure dried and powdered root ordered over the net). I used to prepare a couple of pints from my favourite strain (so called "stoned"), had a pint and then dose 20-40 mg of mxe. Best high ever. And kava, although gabaergic, is not addictive and doesn't decrease your memory.
Best combo.
 
So I've been on/off binging MXE for months now. Basically this consists of me doing it every day for a week, then none for a week or so. Usually when I run out I try to avoid the impulse to buy more, and sluggishly take my time putting another order in so I can get at least that one/two weeks break. The quality of the material over time has shifted as I've had to move from vendor to vendor. A gram lasts about a week if it's crystalline, 3 days if it's tan, and somewhere in between if it's this yellow-white stuff I've been getting domestic recently. Anyways, I went to order 2g from my vendor, and because of a slight delay in shipping he over-comped my order and sent me 4.5g

This was of course a fuck yeah scenario. I gave a friend one gram to comp for some MDMA he bought me prior, and another half gram to a friend. Essentially I've gone through between 2-2.5g this past week (some material being spilled or lost in dissociated moments. I cannot get myself to not do it daily. MXE is definitely the most addictive substance I've come across. As a former heroin addict (clean from heroin 9 months now), that says something. The thing is it lacks significant umph in the negatives of its dependence. No physical withdrawal takes the torture aspect of the addiction out the equation. I work at 7am every morning and have not been late to work ONCE in light of my usage in the night, and I also still hit the gym and intake proper nutrition. It's such a difficult demon.

What I'm starting to notice is some slight alerts that make me wonder if there is some neurotoxicity going on. I feel like my vision has worsened a little bit (though this might be a side effect induced by the blurred vision sticking around since it's been in my system). I'm noticing that my perception of my environment and subsequent depth perception seems to take a second to calibrate. I'm noticing my thoughts seem clustered when I start my day.

I know MXE has known affinity for Dopamine, Serotonin and NMDA receptors. I also take low-dose (40mg) Vyvanse (dopamine agonist) daily. I'm glad that I'm at the tail end of my stash, and looking forward to the forced break that comes after running through it. What I'd like to know is if there is anything additional I can do to help make sure I detoxify the stuff better, and want to know if there's any info that might help in reducing neurotoxicity, or indicate the consequences of possible consequences of this pattern of using the substance. Thanks!
 
There is a link to addiction and side-effect subthreads in the opening post if you'd like to discuss it more there, but that is just a hint to try and help find extra info and others struggling with it.

I don't think MXE has affinity for the dopamine and serotonin receptors but for the transporters, tiny detail there.

To monitor your mental status you could possibly register at a site where you can do cognitive tests and training and see if the scores change over time. Obviously test yourself during MXE breaks.

I occasionally do binge on this stuff, but I am able to just not order it all the time. I'm really looking forward again to it though but the tolerance really sucks after that first 1-2 days. Moreover because it is chronic tolerance doing that.

Racetams seem to counter the effects of dissociatives and the result of types of brain trauma so you could look into that for during breaks - their efficacy for that purpose is hypothetical though. Maybe some milk thistle to detoxify the liver?
 
i had much, much better results using freshly prepared kava kava (made from pure dried and powdered root ordered over the net). I used to prepare a couple of pints from my favourite strain (so called "stoned"), had a pint and then dose 20-40 mg of mxe. Best high ever. And kava, although gabaergic, is not addictive and doesn't decrease your memory.
Best combo.

I just tried Kava for my first time recently and I'm still not sure if I like it or not. I do notice it's affect on GABA but it makes me feel weird for lack of a better term. Maybe it's something you get used to. It's definitely something I'll keep in mind. I do plan on trying Kava again soon
 
Can someone link me to some scholar articles/peer review literature about arylcyclohexylamine SAR and pharmakonetics?
 
Wow how much mxe are you talking? 3 months of daily use and I still was doing the exact same dose with the same effects .. Zero tolerance.

I was vending it and had 100's of G in bags around at all time. I didn't bother weighing it to a point. I knew a spoon fool = the large amount I desired. Every day I came home and took a scoop. I got pure EU quality and even need 300mg at a time to enjoy it. Not proud of the amount over all. Probably did a comple hundred grams since 2011. But when you buy wholesale you look at the stuff and loss the respect of quality and worth. I just saw a large bag of powder.

I also smoke dank weed and nothing was more fun than coming home, dosing, playing with my dogs, doing some house cleaning; redose and puff all night watching [adult swim].

LTS; I'm a fucking drug addict. I know it, but have yet to make the changes in my life to change that. Sadly drugs are my hobby.

P.S. Being broke rocks sometimes; bills are paid and I can't order schtfuff offline ;)
 
Entheo that is not the easiest request, try a relevant ADD / NeuroPharm forum thread and ask there, probably much quicker.
 
Question for experienced dissocia-heads. Ketamine vs. MXE and why?

I'm starting to lean towards MXE. It's much easier on the nose and body. Longer duration. Availability is a plus and the side effects alone compared to constant Ketamine use pretty much sums it up. I've had some amazing K-holes; but I find MXE to be more enjoyable, functionable at the doses.

Let's leave the other compounds out of this; I'm purely curious what people prefer. Obviously it's nice to have best of both worlds, but after this weekend revisting K in over 7 years; I gotta say MXE is far better.
 
ThaDudeAbides so any long-term symptoms due to your heavy dissociative use?
 
ThaDudeAbides so any long-term symptoms due to your heavy dissociative use?

Eye sight. The bright whites never seem to go away. Equilibrium isn't what it use to be. I often stumble getting off my sofa. Otherwise I feel pretty good. Even mental wise my anxiety and depression isn't affected and infact I find MXE to be very medicating.

With all that said. In good faith of Harm Reduction; I share my stories for people to learn that the life I live isn't so grand. As many on here has stated I consume too many chemicals. Sharing these stories though does help me lower the abuse.

I'm currently looking into finding new hobbies that don't involve drugs. It's tough when you've been self medicating for 15 years and it's come a routine. I hope I can provide insight and prevent people going down the route I have. I spend half my income on drugs and it's fucking pathetic. 2014 is the year I finally put bills before my drugs. I can say I am proud to say my dogs never starve. They eat $2 a pound holistic dog food and they come first to me. I would never put drugs before my kids aka dogs.

As I said life as a junkie isn't fun. It has fleeting moments of fun. A good work out will get you higher IMO.
 
Question for experienced dissocia-heads. Ketamine vs. MXE and why?

ketamine wins when talking about effects. the k-hole is just so much more than an m-hole.
but mxe is more multypurpose, easier on the body etc, etc.
they are both great and favorites of mine but the k-hole is "the" experiance!
 
I much prefer MXE to ketamine. Longer-lasting, more potent, more psychedelic, deeper holes and a highly introspective mindstate.



With ketamine you need to do a LOT more (which wrecks havoc on the nose). I do kind it's easier to hole on ketamine, but the hole seems so much more cold and anesthetic whereas MXE is a very bright and euphoric experience. I'd still go for the K if I was rolling, but MXE is really just like a version of ketamine that has improved on everything that K lacks.
 
I much prefer MXE to ketamine. Longer-lasting, more potent, more psychedelic, deeper holes and a highly introspective mindstate.



With ketamine you need to do a LOT more (which wrecks havoc on the nose). I do kind it's easier to hole on ketamine, but the hole seems so much more cold and anesthetic whereas MXE is a very bright and euphoric experience. I'd still go for the K if I was rolling, but MXE is really just like a version of ketamine that has improved on everything that K lacks.

i keep reading and hearing that from people who prefer mxe(the coldness part) and i always wondered why. i do not find either one cold but if any one of them is warm then k is ultra warm(for me).
folley did you start using k or mxe first?
 
Question for experienced dissocia-heads. Ketamine vs. MXE and why?

I'm starting to lean towards MXE. It's much easier on the nose and body. Longer duration. Availability is a plus and the side effects alone compared to constant Ketamine use pretty much sums it up. I've had some amazing K-holes; but I find MXE to be more enjoyable, functionable at the doses.

Let's leave the other compounds out of this; I'm purely curious what people prefer. Obviously it's nice to have best of both worlds, but after this weekend revisting K in over 7 years; I gotta say MXE is far better.

It depends. Ketamine and MXE both get really out there in high doses. I will say that while both are equally bewildering in hole doses, an M-hole is not as comforting. M-holes feel very desolate, and somewhat cold. K-holes definitely have a much stronger push euphorically, and overall a more pronounced or intriguing version of psychedelic/hallucinogenic effects. Overall I'd prefer MXE because of duration, dosing, day-after effects, etc. Cheapest I've ever gotten a gram of K for was $40, but more often than not $60-80. I've gotten MXE for $9/g, more typically somewhere between $15-20. It's twice as potent, so the financial burden is so substantially minute, that it is really difficult not to sway in favor of MXE out of bias. I love K and would never pass up an opportunity to get some, and definitely love how deep and beautiful it gets in high doses. But MXE in the low-medium and medium-high dose ranges is more practical and functional. It's sort of like LSD vs Shrooms. I can't knock either of them, and develop a specific love for whichever one lays fresh on my mind, but I'll always default LSD as my preference.
 
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