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Bupe Suboxone/Buprenorphine Mega Thread and FAQ v16.0

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^^^

The doctors/makers lied through their teeth about suboxone when it first came out. They still lie about it and refuse to admit a lot of things about the drug that have been proven by thousands of users.

Wow, I totally thought this was the case. It all sounded like a bunch of lies. I am another story - a success story. I could not get out of a near 300 a day habit, every time I tried right before the peak of WD I literally could not do it on my own, not able to hold down any fluids or do anything. So I finally tried subs and they brought me out of the crazy WD and I was able to sleep. Finally didn't have to wake up every morning needing to dose an hour before getting up. So I started reading about it and there are many contradictions, like this -

'The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.'

This means that as long as under the ceiling effect it is a very sustainable opiate. All this talk about being a partial agonist, it is probably a full mu agonist in reality, they just push the part about not activating the Kappa receptors but Kappa receptors don't cause euphoria, the mu ones do.
 
As I think about it. How come a .25 is enough to take the edge off and even something I can feel?

If .25 is this powerful right now. I'm going to jump and if by the 3rd day it's horrible I'll just take a .25 and wait out another 3-4 days. Is that no good?
 
If you are jumping at .25 its a good idea to start skipping days first. Take a day off, then do .25, another day off, then .25, then 2 days off, .25 and jump there, or maybe another one after 2 days off and it should help.
 
If you are jumping at .25 its a good idea to start skipping days first. Take a day off, then do .25, another day off, then .25, then 2 days off, .25 and jump there, or maybe another one after 2 days off and it should help.

It will most likely be a jump from .5

I'm already having a hard time with 1mg. Today I cheated and took .25 and I felt the difference. tomorrow .5 sunday nothing. I will keep a few .25's around for emergency's. But I am mentally ready to do this now, and just can't drag it out to .25.

If .5-1mg is too high to jump I will let all of you know!



I also only have 26ish days on sub which I think will make all the difference. I'm almost certain the only things that will happen will be depression and mood swings as the transmitters start getting fired up again.

Possible other minor things. I have all the comfort meds for anything.
 
^Also man, you really need to get to a lower dose before jumping off, down to 0.1mg SERIOUSLY, and then when you get down to that, take a day off with nothing, do that for a week, then take 2 days off, the longer and more time in between doses, and the lower the dose you finally JUMP off at, the easier the withdrawal syndrome will be, and the W/Ds are going to last weeks if not months trust me, especially the protracted withdrawal syndrome part. Then there's the getting used to feeling normal again, which feels alien because you have been under the influence of whatever opioid for SO long, you don't know what normal feels like anymore. Your endorphins are now used to receiving this foreign opioid, so it stopped making the natural endorphins maybe entirely, so now your brain, more specifically your endorphin system has to get used to making NATURAL endorphins again, which will take some good time, very good time, let me tell you. Depending on how long you used, could take years. Same with benzos too, but that's a different story.

I once read that opioid withdrawal syndrome is actually the opioids in the bloodstream getting lower and lower, and the blood pressure, which is normally lower than normal, does a complete 180, and is higher than normal, and that is why the RX drug CLONIDINE (which is used for controlling blood pressure if I'm not mistaken) is SO good at helping people in withdrawal, and thirdly, the endorphins in the brain no longer having the foreign endorphins in there keeping them filled up and happy so to speak, I heard it was a mixture of that. Does anyone EXACTLY what opioid withdrawal syndrome is??

Hopefully someone knows about this. I get my Suboxone brand name tablets in the manufacturer's bottle from the pharmacy typically, so if 90-count script, they'd give me 3 30-count bottles. NORMALLY, the bottles are white, with orange label on it, but today, the label was YELLOW, everything else looked exactly the same, except that color, does anyone know about this, or if there is some difference to this one maybe? I am really curious about this. Thanks in advance!!

I asked this a few pages back, anybody have any ideas about this please?
 
It will most likely be a jump from .5

I'm already having a hard time with 1mg. Today I cheated and took .25 and I felt the difference. tomorrow .5 sunday nothing. I will keep a few .25's around for emergency's. But I am mentally ready to do this now, and just can't drag it out to .25.

If .5-1mg is too high to jump I will let all of you know!



I also only have 26ish days on sub which I think will make all the difference. I'm almost certain the only things that will happen will be depression and mood swings as the transmitters start getting fired up again.

Possible other minor things. I have all the comfort meds for anything.

26 days on sub.....but how many on a full agonist prior to getting on sub? That is a big factor, as well. Its still a matter of the total time on opiates, not on just Sub. And your having a tough time because the steps down in the taper are too big. If you think 1 to 2 is bad, wait until you do .5 to nothing.


I asked this a few pages back, anybody have any ideas about this please?

Is it the same medication in the bottle? If so I don't see what needs to be answered. So the packaging changed.... I get a non narcotic Rx that comes in different bottles on occasion, I do not think there is something up with the medication.
 
Good luck not again. I admire you all cutting it into small pieces n all that. I couldn't be bothered with that. I'll prob jump at 1mg.
 
^ id probably switch to a moderate oxy dose (60-90 mg) for 2 weeks and jump off that than 1 mg of bupe.
 
Nah I'd jump n face the whatever happens. I chose to go down tbis route instead of doing what my parents asked n withdrawing from codeine n suck it to. I chose to listen to some middle aged woman who had been on suboxone over research n warnings from MANY others (so glad I cut her for loose) when I could be over it all n left opiates far behind lime they never existed. So in 2014 I'll have to taper, suck it up n face the consequences.

Evey xxxx
 
Yeah if I knew that jumping from heroin is easier than subs, I would have done that instead.
 
26 days on sub.....but how many on a full agonist prior to getting on sub? That is a big factor, as well. Its still a matter of the total time on opiates, not on just Sub. And your having a tough time because the steps down in the taper are too big. If you think 1 to 2 is bad, wait until you do .5 to nothing.

This run was 7-8 months including the sub taper. Before that I was clean for 4-5 months and felt good. So not a very long time, just got to a very high dose fast.

Welp , I'm going to work, so lets see how the day is.

So far it's just been mood things. I think as long as I get these breaks from it from time to time I can do it.
 
This run was 7-8 months including the sub taper. Before that I was clean for 4-5 months and felt good. So not a very long time, just got to a very high dose fast.

Welp , I'm going to work, so lets see how the day is.

So far it's just been mood things. I think as long as I get these breaks from it from time to time I can do it.

Hi NA,
Your lucky and smart that you didn't use sub long. People on high doses "stack" so much daily that it takes forever to leave their system. You can test positive for sub 22 days after using it.
The moodiness is the worst symptom in WD. I never had any gastric distress, jumpy legs or much physical stuff...but the anxiety and depression really hit for about six weeks. Put notes around the house reminding yourself that your feelings in WD are fake, and caused by the WD. Keeping a journal helps too.
My worst days in sub WD were always day 9-13. That's when you just get SO tired of feeling weak and moody.
Educate your family so they know how to help you.
You have a history of feeling good on clean time...so just keep that goal in your mind...
Your gonna do this!
 
Has nothing to do with ^this quote, but I've been listening to some Bowie recently just because of seeing you BL handle.

Hi ya Train! Glad I could bring back some awesome music for you. Old Bowie was the soundtrack of my youth.
Hey...your name just made me think of Crazy Train by Ozzy! Thanks!
 
Not again, no matter how bad it gets we're here to support you through it ok. There's also some threads on The Dark Side are useful for people going through withdrawals. Not wanting to encourage you away from this threads, just letting you know there's other forms of support on bluelight if you needed them.

Just remember it's a mind thing n you can do this ok you are doing it. You've come so far. There people who find it extremely difficult to get down to 1mg. And 7/8 isn't bad some have taper from years run of opiates.

Take care,
Evey x
 
I have been sticking to the .25 once a day for a couple of days now. Today was a little harder being Sat. Very Bored .Was going to take another .25 in the afternoon today but stayed strong and just got a coffee. What would it be like if a Jumped in a day or two??? Or could I drop to .125??? Yesterday was the first full week without Oxycodone.Been on the low dose subs for a week now.
 
Hiya Mike, I can't answer your question re jumping as I 've not yet jumped. Would just like to say well done. People like you n not again are true inspirations to us all - n when it's my time I'll be sure to read back over this thread.

I do hear you re the boredom. I went into complete self destruct mode the last few months due to boredom n emptiness. I know it's hard but try to think of something which made you feel passionate n happy before the drugs. For me it's exercise but everyone is different.

You can do this n we're all here for you. There 's lots of people who have been where you are.
Sorry I couldn't help further but someone will be around soon.
Evey x
 
I have been sticking to the .25 once a day for a couple of days now. Today was a little harder being Sat. Very Bored .Was going to take another .25 in the afternoon today but stayed strong and just got a coffee. What would it be like if a Jumped in a day or two??? Or could I drop to .125??? Yesterday was the first full week without Oxycodone.Been on the low dose subs for a week now.

The lower the dose you come off at, the easier the withdrawals will be. .25mg's is a fine dose to come off of but if you want to make it even easier, go for it. .25 to .125 is a very big difference if you can make that reduction. That's a 50% decrease in dose, so the withdrawals will be a lot less severe at .125. That was the dose I jumped off at and it really wasn't a big deal. It's pretty painless at that level.
 
My last dose of buprenorphine IV was below 20 mcg

believe it or not I felt it because I did a gradul taper

I'm glad I did a gradual one; this time I think I can do it. Last time I didn't taper as well and it was obviously more hell on earth.
 
My last dose of buprenorphine IV was below 20 mcg

believe it or not I felt it because I did a gradul taper

I'm glad I did a gradual one; this time I think I can do it. Last time I didn't taper as well and it was obviously more hell on earth.

If you're tapering from bupe shouldn't you be at the point that you're like, um, not injecting it? Like if you're actually trying to get off of it why not just take it sublingually?
 
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