- Jan 23, 2020
Interesting Wilson! Thanks for the feedback! I guess I won't toss them quite yet! i wonder if cancelling out any respiratory depression would also cancel out any potential nod? Hmm.Gotta say I was disappointed by tianeptine on its own. I'm assuming the issue is just rapid tolerance buildup, since I so often read of people getting into doses of grams a day, but I hadn't done any strong opiates for months before the weekend just gone and already tianeptine is feeling very weak.
That said it does seem to work well as a potentiator for other opis. If I take it at the same time as DHC for example I will get stronger effects than from DHC alone.
I also noticed when I took low doses alongside oxy on the weekend I got very strong dreamy nods.
Again I would not expect this to last a long time due to rapid tolerance, however instead of throwing your tianeptine away take it in moderate doses alongside other opiates and you should feel a nice synergy.
Also interesting is apparently tianeptine will cancel out the respiratory depression from morphine when taken together. I'm not sure how conclusive this is, I think it's just this one study on rats so don't take it as gospel, but if this is indeed a property of tianeptine in humans it may very well be a harm reduction tool.
Tianeptine prevents respiratory depression without affecting analgesic effect of opiates in conscious ratsRespiratory depression remains an important clinical problem that limits the use of opiate analgesia. Activation of AMPA glutamate receptors has been …www.sciencedirect.com