• Find All Reports by Search Term
    Find Reports
    Find Tagged Reports by Substance
    Substance Category
    Specific Substance
    Find Reports
  • Trip Reports Moderator: Xorkoth

Phenibut - Dosage varies - Best Therapeutic Substance I've Ever Taken

There is the possibility that excess glutamate & low dopamine together with low GABA is responsible for the withdrawal. The (unfortunately currently approved only for Alzheimer's) anti-glutamate and pro-dopamine agent memantine can help very much in many withdrawal syndromes, including GABAergic and opioid. But it seems to be harder to get than it should, as it is a comparatively safe drug.

I looked into memantine before for opioid withdrawal, but also found out it's harder to get prescribed than it should be and I wonder why that is. Back then I was also wondering about it because I was much more into dissociatives at the time and was hoping it might be like DXM in effects. After some searching around the internet the general consensus was that it doesn't act like a dissociative at all, even though it is an NMDA antagonist.

Don't take it too often man.. you will lose the magic completely. I've been off it for months & 2g effects me as such: barely any anxiolytic activity, no disinhibition, no nothing really. Maybe minor mood increase, although i still got the sexual effects (so much so i was able to continue penetration & come a second time.. never happened to me! but my g/f at the time seriously thought i needed sex anonymous b/c i was horny 24/7 & rubbing one out ~3/day). But if id go a tad over? Maybe some music enhancement & some energy.. small increase in libido/sexuality. but even a tad over that (like 3-3.5g; i'm puking for 12 hrs w/ flu like symptoms)

But I suggest if you want to retain your glowing experience you use it sparingly.. i wouldn't even say 2x a week (as most people advise to avoid tolerance/addiction)..i'd say once every 2-4 months.. or for very special occasions when you need it.. holidays, events, special outtings w/ the family or a date (b/c its quite the natural viagra+libido enhancer)

Granted, at my height- i was IM'ing 8g of the stuff (yes took 2.5 rigs..one in each thigh, the remaining in my deltoid)...

Had a huge etizolam habit at the time (425/mg day).. fate (which i don't believe in) intervened & i ingested too much 3-meo-pcp i had laying around, w/ some 5-meo-dalt. Well i was found catatonic & seizuring. Our local shitty hospital said "NO MEDS" on the entrance to my door (not even my subutex). But i was quickly transferred to docs & neurologists who apparently knew their shit over up in Univ of Cleveland hospitals. Put me on my subutex dose; stabilized me on 6mg of lorazepam.. was a week before i started talking..was there for 3 weeks but still don't have any memory of the whole event.

Was only then that it saved me w/ my benzo habit (before kept sending me to psych wards & tapering me in 1-3 weeks regardless of tolerance.. never worked). I tapered off the 6mg of lorazepam in 3.5 months w/o any issues aside from PAWS (much worse w/ benzos than w/ opioids)..in which now i've found myself tapered/weaned off all the ineffective meds they gave me for "depression" (nothing worked, i think i'm in that 30-40% class of AD resistant patients) & on back on a habit of clonazolam since around 9/5.. however, i only take at night 2-3x; & am still functional throughout the day & morning (never any morning doses).. not depressed.. not laying in bed watching TV till 4pm b/c to anxious to leave the house or deal w/ interacting w/ people. Its really been a miracle for me, and my dose has been steady! Finally have confidence back! have several job interviews coming up!

ANYWAY TO YOUR POINT ON PHENIBUT-
When i got out of the hospital (the 3 week stay).. i tried the phenibut again. Nada...zip.. nothing...tried a bit more. 12 hours of flu like symptoms & puking. So don't over do it man. Don't lose that magic..wish i could still reclaim it :| i still do get those sexual side effects though from 2g, they don't seem to diminish for some reason? 8o

I'm actually not really looking to retain the magic with phenibut. I think it's already passed to be honest. The first few weeks were great, but when I got my second tub I took PEA while on phenibut a few times right off the bat and since then it seems phenibut makes me hypomanic. I can't distinguish if this is due to me concurrently ingesting the PEA, if it's because the second tub isn't as pure or contains some impurities, if it's because I was taking phenibut daily for some time, if it's because I was taking such high doses (the hypomania also coincided with when I began taking 10g doses), or if it's a combination of some of these. I believe it's attributable to the high doses and maybe the duration of daily dosing.

Another weird thing though is that around the same time I started to lose that increased libido effect, probably due to said hypomania. I still very much enjoy the therapeutic benefits of phenibut though and, as I've said before, I don't mind the hypomania because it makes it very easy to do tedious work and get stuff done. I still get the anxiety relief, extreme confidence, relief from insomnia and yet I also feel stimulated, and elevated mood.

I've never read of someone using the stuff in an intramuscular fashion before, how did the effects and duration of them differ? I'm sorry to hear you had to go through what you went through, but I am glad that you're at where you are now. I currently only work an under the table job that's hit or miss, so I need to follow your lead and line up some job interviews too haha.

It's looking that I'll never get effects from doses as low as 2g ever again. I was doubtful of this anyway since I was only able to get effects from that dose the first and second day I took the stuff. My new tub should be arriving tomorrow so I guess I'll start with 4g, maybe as low as 3. As I said in a previous post above, when I was withdrawing, I took 5g and felt amazing, but this was probably due to me going from feeling like shit to feeling the familiar phenibut effects again.

I was going to quote your next two posts too, but for the sake of not posting a novel here, I'll just reply. I can second the need to stack doses of gabapentin. When the magic was still there for me, I would take 150mg-200mg of the stuff every 30-45 minutes (either half of a 300mg capsule or half of a 400mg capsule). Some hours later I would start feeling great, it wasn't really a high, but it feels like nothing else and I really enjoyed it. The more gabapentin you take at once the lower the oral bioavailability is. I believe this has been posted elsewhere on this site before, but I found it on a drug information site: "Gabapentin bioavailability is not dose proportional; i.e., as dose is increased, bioavailability decreases. Bioavailability of gabapentin is approximately 60%, 47%, 34%, 33%, and 27% following 900, 1200, 2400, 3600, and 4800 mg/day given in 3 divided doses, respectively." So if you take 900mg/day, you get 540mg. If you take 1200mg/day, you get 564mg...it's almost like you're wasting that other 300mg capsule since you only receive 24mg from it. Last week, when I got gabapentin for phenibut withdrawal, they weren't doing much except easing it a little bit. I was taking 4 or 5 capsules a day, so 1200mg to 1500mg. Then the next day, I took naproxen and a good sized glass of grapefruit juice about 45 minutes prior to ingesting the gabapentin and after taking 600mg over the course of a couple or few hours I felt more than twice as good as I did from the larger doses I was taking the days prior. Albeit I did stop taking the gabapentin after that because I got my hands on baclofen and now the withdrawals have since ceased.
 
TEN GRAMS!? WOW! I thought I was in a danger zone because I'm taking 250-500mg now for two to three weeks. During which time I've occasionally taken every other day. I really like a low dose of phenibut. Has anyone ever experienced w/d with recommended dose for relatively short period of time?
 
TEN GRAMS!? WOW! I thought I was in a danger zone because I'm taking 250-500mg now for two to three weeks. During which time I've occasionally taken every other day. I really like a low dose of phenibut. Has anyone ever experienced w/d with recommended dose for relatively short period of time?

You might feel a slight withdrawal but everyone is different.

If I overuse phenibut during a long weekend I get this thing the next day where everything appears frightening and scary for a couple of hours at certain moments but it's easy to shake out of. Can't imagine what would happen at 10G+ though I've never gone above 4
 
I have gotten fully addicted to phenibut before, many years ago when people were saying it's not addictive, by taking ~3 grams of so every day for about a year. The withdrawal then was pretty shitty, but only lasted a week. Since then I have taken it pretty regularly (like a year after I stopped taking it when I was addicted, I started taking it again less frequently), at varying schedules, and never run into any real problems yet. During opiate withdrawal I would take it daily for the whole time I was withdrawing (and I yo-yoed so this happened many times), and I never noticed any dependence. If I take it like 3 days in a row I will feel a bit negative in my emotions, things feel a little bad and scary, for the next day but then it's gone. I was taking it every other day for months a little bit ago and when I took a break I felt the way I described above for maybe 2 days. I feel like it takes a while for dependence to form with it.

Just out of curiousity would baclofen be relatively the same substance as phenibut?

They're similar but definitely not the same substance. Baclofen helps a lot with phenibut withdrawal though. Also taking too much baclofen feels like taking too much phenibut (feelings of heat inside the body, aches, extreme fatigue and overall shitty body feeling) except worse. I like phenibut more than baclofen for sure.
 
At 1.5 g max. (3x 500mg on different days or 1x 1 g and 1x 500mg on different days) per week it can be used as a nootropic. Otherwise it is useless and will fuck u up epochal times, buddy.
 
Just out of curiousity would baclofen be relatively the same substance as phenibut?

Baclofen is β-(4-chlorophenyl)-γ-aminobutyric acid while phenibut is β-phenyl-γ-aminobutyric acid so they are very similar in structure, but I've taken doses of up to 100mg of baclofen and only experienced relief from the ongoing phenibut withdrawal at the time. I think that if I hadn't tried phenibut, or hadn't been using it daily for over a month, then I probably would have felt effects from baclofen. All I felt was a reduction of anxiety, no elevated mood, no euphoria. It was the best thing for phenibut withdrawal though.

Also, something weird happened with me very recently. I had taken my 10g dose of phenibut then I smoked a cannabis joint. I began to twitch and my muscles were jerking like crazy, A LOT more than the small jerks you get when you first start using relatively high doses of phenibut. This was accompanied by an extremely rapid heartbeat and flushing. I ended up blacking or maybe "greening" out (I hadn't smoked in months either) and woke up the next morning I think in the hospital. To get even weirder, I've been here for over 3 days and I believe the last time I took phenibut was Thursday, but I never went through withdrawal. I didn't take anything to help ease it either. I was slightly shaky yesterday afternoon, but that was it. Now I feel fine.

I'm wondering if anybody knows why cannabis would cause the reaction I had when combined with phenibut and also why I didn't go through phenibut withdrawal which always hits me at 48 hours. I'm wondering if this might be due to me being administered naloxone, but I know phenibut is not shown to act on opioid receptors.

Just out of curiousity would baclofen be relatively the same substance as phenibut?

Baclofen is β-(4-chlorophenyl)-γ-aminobutyric acid while phenibut is β-phenyl-γ-aminobutyric acid so they are very similar in structure, but I've taken doses of up to 100mg of baclofen and only experienced relief from the ongoing phenibut withdrawal at the time. I think that if I hadn't tried phenibut, or hadn't been using it daily for over a month, then I probably would have felt effects from baclofen. All I felt was a reduction of anxiety, no elevated mood, no euphoria. It was the best thing for phenibut withdrawal though.

Why such an abusurd amount of phenibut lol?

10-15g is my sweet spot, any less than that and I don't feel a thing. Well, I could probably feel 8 or 9g and 5g has fully taken care of withdrawal when I was using 10-15g a day. I'm starting to move toward the 15g dose more often, tolerance does build relatively fast with this drug.
 
Last edited by a moderator:
That's SO much phenibut. I've been using it for years and even when I was using it every day the highest I got was 3 or 3.5 grams. With no tolerance 1.5 grams is the sweet spot. Has that shaking thing ever happened to you before on phenibut? I have to surmise that 10 or 15 grams is not good for you... though it's just a guess. I can't imagine that much phenibut... I don't want, it would feel horrific for me. Even a half gram above my sweet spot and I start to get the side effects, which include soreness in my body especially my legs, a really cloudy head, my skin and insides feeling hot (to the point that my girl will remark how hot I feel), and a really shitty passing out type of feeling.

For some reason baclofen hits me really hard, I took 40mg the first time I tried it, and I spent a day and a half feeling like I had too much phenibut except it was even worse. I took 20mg once and felt it a little bit but not bad, but there were also no real positive effects other than muscle relaxation.

You are going to be for quite the withdrawal whenever you stop, I think. If I were you I'd work on reducing your dosage as much as possible.
 
After a little more experience I think I agree now phenibut can inhibit opiate euphoria I had wrote a post a couple weeks ago complaining about this and figured it was just addiction and/or dxm. I now save the phenibut for when the opiates are just about gone from my system it "refreshes" them at the tail end.
 
That's SO much phenibut. I've been using it for years and even when I was using it every day the highest I got was 3 or 3.5 grams. With no tolerance 1.5 grams is the sweet spot. Has that shaking thing ever happened to you before on phenibut? I have to surmise that 10 or 15 grams is not good for you... though it's just a guess. I can't imagine that much phenibut... I don't want, it would feel horrific for me. Even a half gram above my sweet spot and I start to get the side effects, which include soreness in my body especially my legs, a really cloudy head, my skin and insides feeling hot (to the point that my girl will remark how hot I feel), and a really shitty passing out type of feeling.

For some reason baclofen hits me really hard, I took 40mg the first time I tried it, and I spent a day and a half feeling like I had too much phenibut except it was even worse. I took 20mg once and felt it a little bit but not bad, but there were also no real positive effects other than muscle relaxation.

You are going to be for quite the withdrawal whenever you stop, I think. If I were you I'd work on reducing your dosage as much as possible.

I wish I could use doses as low as yours with phenibut, I just can't. It's not like I ever upped the dose by a lot either and the only times I did were when the dose I was taking stopped working due to tolerance which does rise extremely quickly with this compound. I am now up to 15g a day, but will most likely have to raise that number again very soon. Maybe this is due to GABA downstream or who knows, if you think you might know, please let me know.

Yeah, as I've said, baclofen never had any positive effects for me besides taking away phenibut withdrawal, but I actually did stop taking phenibut on Thursday. It's not Monday and I just took another dose for the first time since then because I didn't have access to it due to me being in the hospital. I didn't experience any withdrawal whatsoever though, just some slightly shakiness and maybe a little anxiety. I believe I already touched on this in my previous post, but I can't see it right now.

After a little more experience I think I agree now phenibut can inhibit opiate euphoria I had wrote a post a couple weeks ago complaining about this and figured it was just addiction and/or dxm. I now save the phenibut for when the opiates are just about gone from my system it "refreshes" them at the tail end.

Yeah, I've experienced the same thing. The only effect I felt when I took opioids on phenibut was sedation, but no euphoria. Does anybody know why this is? I had to wait a full 24 hours after my last dose of phenibut to feel those familiar opioid effects.
 
On ten to fifteen g phenibut dose-Doesn't it start to seep from your pores? That much of any one thing has to rid itself somehow, no? Not trying to be offensive here. Seriously curious.

Haha no offense taken, I have yet to notice any negative effects from such high doses of phenibut, save for maybe a little more sedation than usual. Do you take phenibut and if so, how much and how often?
 
I've stopped using this altogether....I have found absolutely zero benifits from it at all from 1-5 grams....too little and I feel nothing too much and I'm just tired. Even at the just right dose it really is just a poor drug
 
I've stopped using this altogether....I have found absolutely zero benifits from it at all from 1-5 grams....too little and I feel nothing too much and I'm just tired. Even at the just right dose it really is just a poor drug

Speak for yourself, I found it extremely beneficial in so many ways. For me, it causes a relaxed, yet stimulated, state of mind and rids myself of any drug cravings whatsoever, it causes an elevated mood, gets rid of any anxiety (I'm not sure if you can have negative anxiety, but that's what I'd call it), but I guess there is one negative effect unless you're bulimic, it induces nausea, but it feels like a refreshing purge and then I feel great after. Maybe what you're getting is of low purity? I get mine from an online vendor that carries a 200g tub that comes with an orange scoop. I'm not sure if we're allowed to discuss specific sources in this sub-forum, but if we're able to, where did you get yours?
 
I have a friend who has never gotten anything good from phenibut either. Maybe it's down to individual body chemistry... for me the right dose is one of my favorite drugs. It's not an outright high like most things, where you're buzzing, instead it just feels like I'm having the greatest day, like when you thought something bad was happening and then realized it isn't and you just feel awesome and euphoric and like everything's right in the world. No anxiety seems possible, I'm smiling and talkative and I laugh a lot and I feel inspired. It also makes me feel loose physically, but with plenty of energy. This effect goes away if I do it too often, and if I do too much it doesn't happen and instead I feel shitty. I get fully to that place probably half the times I take it, the other half I just get a sense of well-being. This is because I really dislike too much and the same dose doesn't always have the exact same level of effect so sometimes my dose isn't enough, but sometimes a little more is too much.

I definitely don't get any nausea from it at all, though I don't from much. Then again I've never taken 10 or 15 grams.
 
I have a friend who has never gotten anything good from phenibut either. Maybe it's down to individual body chemistry... for me the right dose is one of my favorite drugs. It's not an outright high like most things, where you're buzzing, instead it just feels like I'm having the greatest day, like when you thought something bad was happening and then realized it isn't and you just feel awesome and euphoric and like everything's right in the world. No anxiety seems possible, I'm smiling and talkative and I laugh a lot and I feel inspired. It also makes me feel loose physically, but with plenty of energy. This effect goes away if I do it too often, and if I do too much it doesn't happen and instead I feel shitty. I get fully to that place probably half the times I take it, the other half I just get a sense of well-being. This is because I really dislike too much and the same dose doesn't always have the exact same level of effect so sometimes my dose isn't enough, but sometimes a little more is too much. But yeah

I definitely don't get any nausea from it at all, though I don't from much. Then again I've never taken 10 or 15 grams.

I think it has more to do with brain chemistry than body chemistry. Phenibut is definitely my favorite drug though, you're right, I don't feel high either, just enhanced I guess. Yeah after a month and a half of daily use, save for a week when I didn't have any, I still feel euphoric as ever. It's different from any other drug's effects, but I enjoy it the most I think. Actually, I took one 2mg Xanax brand bar earlier tn and felt great, even sorta drunk which goes against what I had posted back 's ways saying it only maybe increased sedation a little. Well this time I was nodding like I had taken an opioid. For me, these great effects never go away and I've been using phenibut for a month and a half, save for a week when I couldn't get any. Yeah, I feel very sociable, talkative, extroverted in general and I was an introvert before so I get euphoria from that alone. I can get through almost a whole 200g tub now without raising my dose and when I do raise it, it's by 500mg or 1g. I actually just got nausea from it a few hours ago, I smoked a cigarette and threw up a few times which was the same as last night while smoking a cigarette. This used to happen to me with heroin too, I would smoke them, throw up, then smoke again and throw up again haha.
 
Last edited:
Yeah, I've experienced the same thing. The only effect I felt when I took opioids on phenibut was sedation, but no euphoria. Does anybody know why this is? I had to wait a full 24 hours after my last dose of phenibut to feel those familiar opioid effects.

There's a couple of old posts on here with research on rats self administering opiates while dosed on phenibut, many of them stopped doing it more often than those that weren't on phenibut. It must block some type of shared receptor? It increases other aspects of the opiate high like pain killing, sedation and disorientation not really that great but it can fool you into thinking it's potentiating your high.

Might be useful for those interested in killing pain but not getting euphoria. This might not be the case with all opiates either like suboxone.

Who knows. The more I experiment with this stuff the less I like it, it's useful for what it is a legal valium type drug with little euphoria but it's effects are so unpredictable. Since I don't enjoy Gaba drugs the only use I've found for it is as a withdrawal aid when I'm not using opiates. 500mg with an NSAID and some loperamide, I'm good to go.

Some of you guys alarm me I ordered a tube of 100G and still have half of it left after months. I use it every week.
 
To me phenibut is absolutely nothing like benzos at all. I don't like benzos, to me they have virtually no euphoria (some more than others, etizolam for example - while not a benzo per se - produces euphoria for me). Phenibut produces in me, like I said, a state where I feel like I am having the greatest day. Euphoria, anti-anxiety (utter elimination of anxiety generally), and relaxation and stimulation at the same time. It only works if I get the dose just right but I know how to do that due to experience with it. The first 4 or 5 hours is just a light sedation and minor anxiety relief, and then it develops that beautiful euphoric state if I have dosed correctly. If I want to be on phenibut for something, I take it 6 hours before I plan to want to feel that way. In particular I like to use it when I play shows with my band because it just gets me SO into the music and inspired.

It's probably not for everyone but it sure works for me.
 
To me phenibut is absolutely nothing like benzos at all. I don't like benzos, to me they have virtually no euphoria (some more than others, etizolam for example - while not a benzo per se - produces euphoria for me). Phenibut produces in me, like I said, a state where I feel like I am having the greatest day. Euphoria, anti-anxiety (utter elimination of anxiety generally), and relaxation and stimulation at the same time. It only works if I get the dose just right but I know how to do that due to experience with it. The first 4 or 5 hours is just a light sedation and minor anxiety relief, and then it develops that beautiful euphoric state if I have dosed correctly. If I want to be on phenibut for something, I take it 6 hours before I plan to want to feel that way. In particular I like to use it when I play shows with my band because it just gets me SO into the music and inspired.

It's probably not for everyone but it sure works for me.

Yeah I forgot about listening to music. Bar none the best substance out there for listening to music.

Most of my social anxiety is psychological so I don't really get too much out of the anxyiolitic properties.
 
It's even better for playing music... just puts me right in that inspired flow.
 
Top