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Shambles replied to the thread The Hip Hop Thread. -
NBTW someone mentioned a friend abusing SR17018 by vaping it. The reason being the slow onset was because the pKa meant less than 1% was...
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mr peabody replied to the thread CHRONIC PAIN | +80 articles.Ketamine in acute and chronic pain management* Orhurhu, Roberts, Cohen | NCBI Originally used and approved for general anesthesia... -
Shambles replied to the thread The Hip Hop Thread.
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nasir~ reacted to fastandbulbous's post in the thread What opiates have been proven in studies to be more desirable than morphine? with
Like.
Dipipanone (& cyclizine) is quite spectacular in the euphoria it produces (and all without a queasy tummy!), although the cyclizine does... -
nasir~ reacted to Smyth's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
According to this document on the physical dependence of ohmefentanyl, fentanyl is less addictive than morphine, although it doesn't...
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nasir~ reacted to negrogesic's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
Perhaps it is because morphine and semi-synthetic phenanthrenes also have definate affinity for the kappa and delta receptors, producing...
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nasir~ reacted to JimiHawK*'s post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
can anyone clarify what actually causes euphoria (from opiates at least)? Because i don't undertstand why even though the fentanyls have...
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nasir~ reacted to Mr Blonde's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
Lol, about the only true statement Pimp made was that methadone is not a true opiate. But, as you pointed out Ham, that's only because...
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nasir~ reacted to mad_scientist's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
Fentanyl and its derivatives are generally agreed to be more addictive than most other opiates, but thats more because of the short...
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nasir~ reacted to Ham-milton's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
You're very confused. Methadone is absolute an opiate, or rather opioid. It causes no release of serotonin. It has very high affinity...
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nasir~ reacted to negrogesic's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
? Where do you hear these things? Methadone affinity for the MOR is quite high, probably something in the ballpark of 10nM. It also...
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nasir~ reacted to negrogesic's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
Methadone? Perhaps only if IV'ed.... There are numerous opioids that are subjectively more desirable than morphine, and an even greater...
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nasir~ reacted to Canis aureus's post in the thread What opiates have been proven in studies to be more desirable than morphine? with Like.
Methadone ;)