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Zofran (ondansetron) & 2C-I / 2C-E

PsychedelicDoctor

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Jan 3, 2009
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I used the search feature but could not find anything terribly relevant. A few reports of oral Zofran relieving nausea caused by the 2C-E, nothing about 2C-I.
Anyway, body load/nausea has always held me back with these substances, grounding me to my physical form. Not terribly pleasant, although it usually drops off after a few hours and definitely improved when I quit smoking cigarettes. Can't smoke marijuana which i think does help.
I have several vials of injectable Zofran (ondansetron), a 5-HT3 antagonist used most often post-surgery and chemotherapy to combat nausea. I will be using 20-22mg of 2C-I tomorrow and want to know if anyone has had any success with this, especially IM.

Thanks!
 
It should work just about as well as any anti-emetic can be expected. NewMoonRecord used to post about his experiences using it to combat nausea from mescaline cacti. I've used it for the same effectively. For nausea relief with little to no subjective interference with the trip selective 5-HT3 antagonists are about as good as it gets as far as I know.
 
It should work just about as well as any anti-emetic can be expected. NewMoonRecord used to post about his experiences using it to combat nausea from mescaline cacti. I've used it for the same effectively. For nausea relief with little to no subjective interference with the trip selective 5-HT3 antagonists are about as good as it gets as far as I know.
This and no its not available OTC.
 
I have this stuff Zofran and loved it. I thought it was a fucking flu miracle pill. Then I looked at how it interacts with my daily Methadone on Drugs.com interactions list---it was in the red as not worth taking. Im saying this because it mentioned leading to prolonged qt intervals? I would probably just EAT ginger but I am curious as I do want to try this 2c-e I have around but nausea concerns me Big Time!
 
Thanks for the replies everyone. I appreciate it.

I was going to give this a spin yesterday with 18mg 2C-I but my friend was more interested in a sure-fire celebration of life. As such, we went with LSD and some 4-subs. Seriously swell time :D.

I will get around to this before the summer and will be sure to dig this one up to report the experience.
 
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