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you're sooooo high right now and want to share? post here

god damn i haven't beenthis fucked up in awhile. 3 bottels of some good australian merlot and lots of opills, klonopin and valium. the drum and bass is fucking my haed up, i love it!!!
 
Okay yep now I know I am left to die it's very very sad

Will I die for this? yes....but not that I want to

Okay 200mg adderall on thursday which started it then Friday 175mg adderall saturday 220mg adderall

*hands are trembling sticks* well I have to work at 630am so I already made the parachutes

80mg adderall at 630am then 60mg at 11am on break

So by 11am I will be on 140mg then get home at 2pm then we will see if I have to go over 200mg or not but yeah tomorrow after 2pm when I reach 200mg tomorrow

I am Done hopefully sleep tomorrow night in my opinion 84 hours is enough

Tomorrow at 11am is the 72 hour mark yep that little 3 day line mark but I don't know what else to say

Things have to change starting Monday seriously how long can I keep this up? oh well I will either calm down-to 100mg daily again-or less-orrr never listening, sooner or later I will break and I will collapse Then what?

lalala
 
Ryan, maybe you should leave the city you live in.
Start over somewhere far away ... you're in the US, there's LOTS of great cities to go live in.

You need a change of perspective I think ... otherwise I fear it won't be long before you're posting on the Dark Side till one day you just committ suicide.

I know what it's like to be a drug addict - I'd suggest you tell your friends to detox the shit out of you, if they're good enough friends they'll do it.
 
Ryan. Seriously man. You need to get yourself together.

If you continue using the way you do, your tolerance is only going to continue rising and your dosages will accordingly have to rise. And we should know by now that higher dosages mean more damage to your body/mind.

Originally posted somewhere in DB

Amphetamine tolerance is caused by excess Ca++ influx through the NMDA receptor gated calcium channels on the outer membranes of the dopamine cells bodies in the ventral tegental area, one of two areas in the brain with concentrations of dopamine producing neurons.
As alluded to above, taking an appropriate NMDA (partial) antagonist will prevent the development of a tolerance for the effects of an amphetamine or amphetamine-like stimulant. Also, by preventing excess Ca++ influx into the neuron, an NMDA antagonist will prevent associated brain alterations and damage (excitotoxicity).

Studies have indicated that amphetamine tolerance is prevented by exogenous or endogenous agents that are able to inhibit excess Ca++ influx into the neuron through the gated calcium channels on the neuronal membrane that have NMDA subtype glutamate receptors.Glutamate , the body’s major excitatory neurotransmitter, opens the gated calcium ion channels upon attaching to the NMDA receptor. A number of other receptors are also expressed on these calcium channels, which, when stimulated, either facilitate or inhibit glutamate’s action.

It is also important that agents that inhibit calcium channel activity not also cause deficient Ca++ influx. For example, ketamine is a full NMDA receptor antagonist, that prevents excess Ca++ influx and amphetamine tolerance. But being a full NMDA antagonist, ketamine in excessive doses results in deficient Ca++ influx. This could be one of the reasons it leaves K-user in a state of disassociation.

So basically we have following NDMA antagonists:
1. Memantine (Akatinol/Axura)
2. Acamprosate (Campral)
3. Amantadine (Symmetrel/Amantix)
4. Magnesium (supplement)
5. Dextrometorphan/DXM
6. Ketamine
7. PCP
(funny that 5,6,7 are recreational drugs)

Two of them have minimal (or none) side effects and have been identified (and verified by one anecdotal person, which has been taking amphetamine-type stimulants and NDMA antagonist with same beneficial effects for a period of 2 years) as preventing amphetamine tolerance: 1) Memantine and 2) Acamprosate.

1) Memantine is a partial NMDA antagonist that effectively puts an upper limit on Ca++ influx without compromising healthy levels of Ca++ influx. Memantine is not available in the US at this time. It is in stage 3 trials for Alzheimer’s disease. US approval may come within the next 2 years. Memantine is now approved in the European Union for the treatment of Alzheimer’s. It has been marketed in Germany since 1978 for the treatment of dementia and other cognitive disorders. It comes in 10mg tablets. One or two tablets/day are sufficient to prevent amphetamine tolerance, overactivity of the NMDA receptor and consequent free radical stress inside the neuron. The most expensive option though.

2) Acamprosate (n-acetyl-homo-taurine) analogue of the amino acid taurine. Alternatively, it may be termed as a carrier molecule for taurine, that allows taurine to readily cross the blood brain barrier, unlike taurine itself. Taurine is a NMDA receptor antagonist. Acamprosate is an investigational drug in the US, undergoing stage 2 (?) trials for the treatment of alcoholics. It is available in most European countries as a treatment for alcoholism, with great efficiacy. Cheaper than memantine, however efficiacy should be the same.

3) Amantadine, originally used in the treatment and prophylaxis of influenza infection and drug-induced Parkinsonism, also blocks NMDA receptors. Besides it is beneficial in traumatic head injury, dementia, multiple sclerosis,cocaine withdrawal and depression. Amantadine appears to act through several pharmacological mechanisms, none of which have been identified as the one chief mode of action. It is a dopaminergic, noradrenergic and serotonergic substance, blocks monoaminoxidase A and NMDA receptors, and seems to raise beta-endorphin/beta-lipotropin levels. I couldn't find what amount of the drug should be used to block NDMA. Cheaper than Acamprosate. No one has tested it yet, but I think it would be a good choice.

4) Magnesium is also an NMDA antagonist. Most people are deficient in magnesium, and stress reduces magnesium levels. Whether or not one takes amphetamines, magnesium supplementation is very important for mood, general well-being and keeping stress levels under control. It is also important to take magnesium in efficient form, with adequate bioavailability. The best type is magnesium glycinate (chelated) with bioavailability at around 80%. Second best is magnesium carbonate with (I don't remember exactly) bioavailability at little above 30%. Supplemented magnesium should be at 500 mg/day level. Also there is a study which shows that children who use amphetamine-type stimulants have bad magnesium/calcium balance. Calcium levels stay the same with amphetamine usage, but magnesium levels drop.

5) DXM - definitely the cheapest option of all NDMA antagonists, but I'd rather use Memantine or Acamprosate. Although, I've heard anecdotes that doses as low as 70 mg/day are enough to block NDMA - I couldn't find those amounts in abstracts/studies.

6) and 7) I wouldn't use as an amphetamine tolerance prevention. Ketamine for its known effects (you wouldn't want to be in a K-hole during the tweak just for the sake of prevention tolerance)
PCP - this one doesn't need explanation. It has nasty side-effects and I've mentioned it just because it is a NDMA antagonist.
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gugglebum said:
Ryan, maybe you should leave the city you live in.
Start over somewhere far away ... you're in the US, there's LOTS of great cities to go live in.

You need a change of perspective I think ... otherwise I fear it won't be long before you're posting on the Dark Side till one day you just committ suicide.

I know what it's like to be a drug addict - I'd suggest you tell your friends to detox the shit out of you, if they're good enough friends they'll do it.
Click to expand...


Woah! stop all the over reacting

Uh Riiight I'm 17 I am not moving any where are you nuts?

No that is not true and just over all dramatic

I do not want to go through detox and uh I don't have friends only people I get the adderall from and the one real friend I have is very angry at me right now so it's avoid-avoid-avoid-into the void
 
I seriously agree

Or cut down not 200mg daily doses

Hmm tomorrow I will play the recovered game and go and smoke pot

Maybe only 60mg adderall tomrrow ARGHi have to sleep tonight then or else this isnt' going to work okay

I might just take sleeping pills or something 72+8=80 soo right now I am around 80 hours Strangely enough! I'm not tired
 
ryan, ryan, ryan...though I love your rambling posts and I am pretty sure you are probably a very intelligent young man, redhaze is right: your tolerance is going to go through the roof. I don't recommend switching to a different drug, since it appears as though you have more than just an addiction to adderal but instead an addiction to gluttony. More issues than my fingers can wrap around--really, take 2 days off...smoke copious amounts of weed, follow redhaze's reported guide, work out, eeks--sleep...but reevaluate and let your tolerance drop.

400mg adderal in a day is both wasteful and stupid.

Yikes.

swybs
 
Ryan M, i think you need to get laid and laid good. I do care about you, lots, but if u dont stop this repetitive twittering, im going to hire someone to inject u with a near lethal amount of smack to calm u down and possibly make u forget when u awake.Im serious. This is for your own good so sTFU and get help NOW.

:X

on another note...man, i iz fuxXord WoOT!!!!!!

peace.
<3





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K'dOUTinAZ said:
Yer a knuckhead. Yer not wanted in des parts of town. You want me to do what now? But that costs thirteen quarters in which I spent all on soda pop. Please don't go in there. I think there is a monster in the closet. I don't think that you think that you are thinking right now. Tell me if you think that you are thinking? Then tell me why Mia is in that position in which the position consists of few positions with one position that even relates to the current position. She asked me what time it was. I told her that it was 2AM, and said "Okay I get it, I have to go home right now, goodbye my only love, the gun is loaded, the pills are by the bed, the magazine is extra if I can't hit the intended target. Would you like to witness me die?" I told her that association of the dissociation is a suggestion of association with the eye of the beholder who associates with the dissociative. "Maybe I will wait another hundred years, I mean shit....I don't like cocaine anyway"
Click to expand...

See, you gotta be more like K'dOut....he can tell us how fucked up he is without even directly saying it. ;)
 
UHHH like 250mg-350mg diphenhydramine yeahh this s o hard to type right now well that's pretty much it

wow musixc is so great i' it's like I am AT the concert right there but yeah it sounds so great and I' not really that tired since the adderall keeps me up but I know I will sleep later WOAH *scared* don't ask me what that was AHOSUFHSOURS *hides*

I'm so scared and I don't know why myu crazy room
 
Ryan, please don't use diphenhydramine to get "high", the effects are due to a form of toxic poisoning the chemical has on your brain. It just starts fucking up chemical reactions.
 
I'm doing good I'm only on 120mg adderall + I smoked pot since I am friends again with DJ hmm also I have 670mg adderall+I got paid

*thinks* 160mg seems okay for today.
 
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