Opioids Year after sublocade, dull effects, bioavailability questions

[RudeRicky420]

So my last sublocade shot was November (300), December (100), January (100).

I had surgery and decided to get a buzz while killing the pain (I know it's a slippery slope)

The weird thing is I don't feel the oxy like I remembered back in the day. 25mg chewed OC not OP would get me jacked. Now idk what's going on but I did 40mg and felt good but I was glowing/itching like 15 years ago.

So I'm convinced that the sublocade is still somehow in my system or my receptors haven't gone back to normal yet.

Something I'm confused about is everywhere people are saying the bioavailability of oral vs rectal is either about the same or oral is higher. I remember back in the day when I couldnt feel an 80 if I ate/snorted it, but I got a great buzz if I plugged it. Shooting was never really my thing. I plugged 40 today and expected to be rocked, but no nothing crazy. Felt like I ate 15-20mg back in the day. I always felt like rectal was higher BA than oral.

I have cimetidine and grapefruit juice. (3) Oxydolor 80s and half an OC40 left. I would really like to catch a really good buzz but I don't want to accidentally OD. Is it a thing that you can OD when you're on bup but not ever get high? You just stop breathing or have a heart attack or something?

Also, if anyone is able to weigh an Oxydolor 80 with a mg scale and let me know exactly what it weighs, that'd be awesome. I've never seen these before but from everything I've seen I think they are legit. I always like to be sure though. I ran out of fent test strips so I wanna get a weight, measure the pill size and start with a very small amount to see if it's hot.

Thanks

 

[WillSmithFromPulpFiction]

Legit decided to finally make an account here to reply to this. But I wish others had first, because I’m in the same spot as you… sort of. I did 100mg shot and then they gave me an entire 300mg more 2 weeks later. This occurred in July 2025.

Huge huge mistake. As usual, I was given no information about how potentially long even one single 100mg shot can be death gripping your mu opi receptors for… apparently a single 300mg shot in and of itself can be active and detectable in a urine test for roughly a year. So I suggest, if feasible and subject to how much money you’d like to blow, just keep testing yourself for buprenorphine.

All I want is to be able to enioy regular ol low dose kratom powder again. I did take a 7-oh 15mg and felt fucking great. However, attempting to repeat that effect for the next feed with increasi by lay higher and higher doses really didn’t do much, if anything relative to the first one. Due to both its obvious quick tolerance and being a partial mu agonist I would suppose.

But, it was definitely not a placebo. So… it’ll happen itll just take a long…long time. But you will get there. I just hoped it would be sooner rather than later for me. And that hope was crushed reading your experience