Misc Xylazine withdrawal sucks!
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Them Witches
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Doesn't take ,much hate to ruin a place's reputation. There are other places I have an interest in seeing before the reaper.
As far as my understanding our H is from the Golden triangle and commonly known as Thai white
Señor Moreno
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I know nothing about these parts of the world, but I do think that they might have the two kinds, white and brown heroin.
Recently I did read some report in Al Jazeera (by the very alarming title of "kids whose inside are destroyed: the return of drug abuse to Mauritius". Apparently, heroin is a big thing in those islands and they did blame the islands' geographic situation, halfway between Afghanistan and S and SE Africa, the report said. So they would be reciving both from Afghans and SE Asia, as Coffeshroom said
Recently I did read some report in Al Jazeera (by the very alarming title of "kids whose inside are destroyed: the return of drug abuse to Mauritius". Apparently, heroin is a big thing in those islands and they did blame the islands' geographic situation, halfway between Afghanistan and S and SE Africa, the report said. So they would be reciving both from Afghans and SE Asia, as Coffeshroom said
Just replying to amplify this. Fentanyl citrate is the medical form, street fentanyl is likely to be some (possible variety) of simpler counterions.
Flash chromatography might do the trick as they seem to have differences in lipophilicity. Though flash chromatography takes some practice, it’s not horrible, and you could practice using things like black marker pigments to get the hang of separations.
4DQSAR
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My first though was that the secondary amine in the xylazine molecule could be converted to an amide so a B/A seperation might work. I presume your solution is better and TBH I'm not sure if telling people to play with anhydrides, diyls or acetyl halides would be a good idea.
Xylazine is a pretty closely related drug to Clonidine (Catapres). As an A2-Adrenergic receptor agonist, a primary effect would be the reduction of blood pressure. Clonidine (Catapres) within the relatively great complexity of pharmacology seems to fit in well with treating withdrawal symptoms. It reduces blood pressure, this can play into the psychosomatic loop leading to a person feeling more relaxed and thus, being more relaxed. Higher doses are going to have a distinctly narcotic effect, this goes for both Clonidine and its relative Xylazine.
Neither is really a drug with addictive properties. Neither would typically be sought out for a drug experience by anyone outside of a penitentiary. Xylazine was a great way for the dealers to make their product appear to be more potent than it actually is, that is, tricking you into believing you are getting a certain total amount of Opioids.
The problem is, they are not addictive, but the withdrawal is bad. It is the equivalent (I have experience) of an anxiety attack that persists throughout the course of hours or even your entire day. It is a condition easily quelled with this "non-addictive" medication, however, addicts today are more alienated from services than they have been in the past decade. They just don't have access to anything to make them feel better other than more Dope. They aren't going to show up Tuesday the 19th at 1:30pm with a 1:15pm check in to be judged by some schmuck for a Clonidine prescription.
My point is, think ahead. Know that Clonidine has the potential to relieve some of the major issues arising from combined withdrawal from Fentanyl. It can be enough to take the edge off enough for you to make whatever moves you need to make to keep yourself going for another few hours. There is not much we can do about the local supply of Dope. It's positively toxic and some places are much worse than others.
I never realized, sitting in that 1987 Toyota Camry, run out of gas on the Highway Turnoff with 3 other junkies on a 93 degree day in Boston with 3 other junkies were going to be referred to as the "Good ol' Days".
Neither is really a drug with addictive properties. Neither would typically be sought out for a drug experience by anyone outside of a penitentiary. Xylazine was a great way for the dealers to make their product appear to be more potent than it actually is, that is, tricking you into believing you are getting a certain total amount of Opioids.
The problem is, they are not addictive, but the withdrawal is bad. It is the equivalent (I have experience) of an anxiety attack that persists throughout the course of hours or even your entire day. It is a condition easily quelled with this "non-addictive" medication, however, addicts today are more alienated from services than they have been in the past decade. They just don't have access to anything to make them feel better other than more Dope. They aren't going to show up Tuesday the 19th at 1:30pm with a 1:15pm check in to be judged by some schmuck for a Clonidine prescription.
My point is, think ahead. Know that Clonidine has the potential to relieve some of the major issues arising from combined withdrawal from Fentanyl. It can be enough to take the edge off enough for you to make whatever moves you need to make to keep yourself going for another few hours. There is not much we can do about the local supply of Dope. It's positively toxic and some places are much worse than others.
I never realized, sitting in that 1987 Toyota Camry, run out of gas on the Highway Turnoff with 3 other junkies on a 93 degree day in Boston with 3 other junkies were going to be referred to as the "Good ol' Days".
Them Witches
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I wanted to share with you your post was spot on and the "highlighted copy/paste phrase" has nothing to do with my reply. I just had to pick something.
For 26 years, I have had a Clonidine Rx. Currently, my daily dosage is 0.9mg by three 0.3mg IR tablets. Recently at the hospital, the heart doctor of all doctors thought it would be his best judgement to cold-turkey me from Clonidine Rx at my daily dosage. Professional medical judgement to equivalent to not having enough sense to stand-up in a mud puddle. The withdrawals were horrible, intense, and close to life threatening.
At my dosage which is considered high, gives a 2.5-4 day withdrawal episode compared to peak Methadone WD mixed with Benzo WD. Here is my report for science :
> anger to rage anger
> Restless Leg Syndrome w/ intense thrashing and periods of "fixed hyper extending" the ankles
> electric type full nervous system chills/shocks (hot and cold), 50% happen in a jolting fashion traveling from head to toe like a "repeated tic"
> rebound blood pressure & pulse, those without this chronic BP/Pu issues, expect high pulse rates 127-155bpm resting
> insomnia
> uncontrolled shaking, almost thrashing like, typically 1-2 limbs at a time
> sweating
> high body temps
> bad anxiety
If Clonidine withdrawals lasted as long as some opioid WD's, there is no possibility without medical intervention admitted into care. With the intense shaking and electric nervous system chills/shocks/jolts & abnormal vitals, the chance for seizures &overworked SNS issues put the patient at a high risk.
More medical studies are needed regarding Alpha-2 abuse (unknowingly or not), withdrawals tools, and harm reduction tools.
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4DQSAR
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I was lucky in that I can still recall the opening sentence in the first lecture I attended concerning sedative/hypnotic medications.
'There is no such thing as a CNS depressant that will not eventually produce physical dependence'.
I suppose if a CNS depressant is dysphoric, it's less likely to be abused, but it is omteresting that some 37 year later, the statement remains true. I suppose the lecturer looked back centriries if not millenia and noted that yes, we even have remarks attibuted to Hippocrates as saying much the same.
So was 'tranq' chosen for it's ability to induce even worse addiction?
'There is no such thing as a CNS depressant that will not eventually produce physical dependence'.
I suppose if a CNS depressant is dysphoric, it's less likely to be abused, but it is omteresting that some 37 year later, the statement remains true. I suppose the lecturer looked back centriries if not millenia and noted that yes, we even have remarks attibuted to Hippocrates as saying much the same.
So was 'tranq' chosen for it's ability to induce even worse addiction?
Yeah and that's why so many south africans are immigrating.. hmmm
Sidenote connected to post you quoted: grass is not always as green as ppl make it believe, sad if the world really knows what's going on here. Bet you will think twice then..
4DQSAR
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It's not as if South Africa wasn't an extremely violent nation for many decades. Some of the major cities in SA have murder rates only comparable to some US cities.
St. Louis 69.4 murders per 100,000 residents (2024 data).
Cape Town 63 murders per 100,000 residents (2024 data).
But it's nothing new in either case.
As I understand it it's the sheer size of South Africa means it's population density is even lower than that of the US and it's economy miniscule compared to the US so the cost of policing is an issue for them. I do know that many police officers in South Africa have found themselves alone with the nearest help over 100Km away. Truly frightening.
It IS farmers who are seeing a large up-tick in attacks but that appears to be regardless of their heritage. With no law enforcement and no neighbours to help, they essentially need to tool up to deal with attacks. Of course, while technically easy to obtain firearms in SA, a LOT of illegal arms are also being sold.
There is that nut-job EFF communist guy who appeals to a certain demographic but essentially it's a criminal organization that does a little (extreme) politics on the side. But sooner or later they will become a proscribed organization. I mean, being a political party in a nation where most people don't have credit cards means that cash donations wouldn't look too odd.
I'm gonna reply to 2 points you raised and the rest I will leave alone as i will be seen as a racist, but he'll one point is already gonna make me look like one and the funny thing is, I'm the exact opposite but theses things happened to me or family cause of "shit laws" passed and broken promises not kept. Anyhow I don't want to get political so this will be my only input on this..
I come from a long lineage of farmers and today we are all suburban dwellers or have already immigrated. Why? Cause of land grabbing and the most brutal violent crimes happening on our farms atm and past and the worst it's happening to old defenseless folks. So nr ,1 why we sold all our farms as we saw it coming. ( I'm stepping into dangerous territory here ). And our last family farm was sold 5 yrs ago. Even though it was just a small equestrian estate and pvt horse school, the area it was, it is just a matter of time.
Nr2. Another thing I will comment on, is yeah. Police are underpaid, understaffed and so on, that opens doors to other things.
daturetard
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Because the yohimbine has 'abuse potential' as opposed to naloxone, which is the obviously just gonna maybe give you hyperalgesia for a few minutes, if that. The govt'd rather let people die than supply them something else that might be used as a psychoactive drug.
Also its kind of dangerous in excess, so the govt probably thinks itd be like having otc atropine for nerve toxins. Funnily I knew a kid in high-school who would steal narcan from pharmacies or just aid groups and schnif it for 'fun'.
4DQSAR
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You said nothing but the truth without assigning blame to race - so that isn't racism as I understand the term.
I'm just glad you WERE able to sell your land which I appreciate must have felt awful, especially if it's been in your family for generations.
BTW I am reminded of 'Boris' who is mentioned in the Spalding Gray film 'Swiming to Cambodia'. If you don't know the film, I assure you it is not criticism. Far from it.
Them Witches
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The old Latin phrase "The grass is always greener on the other side of the fence" refers to do with envying another man's fruitful harvest. The phrase's deeper meaning is about envy and perception referring to "How quick we are to see the negative in our own place (lot/property), everything else looks better."
The grass isn't greener on the other side, it's greener where you water it. I like this phrase because it removes the chasing of a perceived ideal (notion) outside of oneself. The thief of self-perception and the block-aid of personal quests that birth foundations of personal discovery & forming personal opinions.
Believing another's view from behind a light blocking solid fence could the quickest way from A to Z, then again not. Human beings tend to trend lead by comparison "the thief of joy." Why does South Africa still have heroin #3 & #4 and the USA only has shitty fetty tranq-dope? Well this is not a good comparison to what I am saying. One cannot simply live our life's from other's opinions or views. We have to locate a hole in the light blocking fence and see for ourselves.
Basically, the "grass isn't greener" idea underscores the importance of self-focus, acceptance, and steady working towards building a good fulfilling life in health, recovery, giving, rather than chasing a perceived ideal outside of ourselves. I am sorry for taking the thread to a sentimental level lol... Here is some humor to leave off with ;
"The grass is always greener when the seed is planted directly above shit."...... Them Witches
The pure vent I got off the darkweb 10 years ago was actually alphamethylfentanyl hydrochloride
4DQSAR
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The 'original' George Marquardt product.
Tell me, is it true that unlike 'plain vanilla' fentanyl, the duration of αMF is much more akin to, say, morphine?
I read about it and I'm sure it's not a surprise to learn that one enantiomer is far more potent than the other. But the problem is that the less potent enantiomer has a lower TI than that 'plain vanilla' I alluded to.
BTW GM made meth first, right? Would it surprise you to learn that BMK (the key precursor to speed manufacture) is the key precursor to αMF synthesis. I mean, if your reason for posessing BMK is to produce the then legal αMF, that would be a clever thing to do.
Don't get me wrong - the guy just read a patent. Fentanyl synthesis is a bit harder than speed synthesis, but it's less complex than say benzodiazepine synthesis. So claims of producing AZT may be apocraphal. One of the precursors is an explosive and I think it's got mixed up with claims that he also supplied nerve agents/explosives/napalm to survivalists. I'm sure in his mind, claiming you possess an explosive to produce a HIV medication would possibly avoid being accussed of supplying explosives. Oh, and said precursor is also toxic. So I think he told different people different stories but at the end of the day, money was what drove his actions.
The man could equally have been producing dull but life-saving medications that were still subject to patent protection i.e. the inventors could ask for a 1000% profit on the stuff. But that would be dull, wouldn't it?
Tell me, is it true that unlike 'plain vanilla' fentanyl, the duration of αMF is much more akin to, say, morphine?
I read about it and I'm sure it's not a surprise to learn that one enantiomer is far more potent than the other. But the problem is that the less potent enantiomer has a lower TI than that 'plain vanilla' I alluded to.
BTW GM made meth first, right? Would it surprise you to learn that BMK (the key precursor to speed manufacture) is the key precursor to αMF synthesis. I mean, if your reason for posessing BMK is to produce the then legal αMF, that would be a clever thing to do.
Don't get me wrong - the guy just read a patent. Fentanyl synthesis is a bit harder than speed synthesis, but it's less complex than say benzodiazepine synthesis. So claims of producing AZT may be apocraphal. One of the precursors is an explosive and I think it's got mixed up with claims that he also supplied nerve agents/explosives/napalm to survivalists. I'm sure in his mind, claiming you possess an explosive to produce a HIV medication would possibly avoid being accussed of supplying explosives. Oh, and said precursor is also toxic. So I think he told different people different stories but at the end of the day, money was what drove his actions.
The man could equally have been producing dull but life-saving medications that were still subject to patent protection i.e. the inventors could ask for a 1000% profit on the stuff. But that would be dull, wouldn't it?
emkee_reinvented
Bluelighter
Just keep it at 'Rooi-Bossie' and save places
Is what i make of it, or wake robbed and naked !
What s Bakaka ... any relevance with Kakalawaka ?
Argentinian for Bullshit. Bakaka, or does it have to go on.
Firstly I was not insulting, but foreigners doing the backpacking exp in S.A. should just be careful that's all. A lot of conmen and more out there.
Personally I have back packed most of south africa and know all the best spots..
Oh as for bakakakakaka, just a laughing typo ppl use here.
emkee_reinvented
Bluelighter
Non taken or interpreted as, get the careful part.
Even within Europe, Paris or travelling through.
Alway s keep one eye alert on bagage, pick-pocker s a.o.
Thought bakakakakaka was a South-African word.