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Would this set me back?

Folley

Folley

Bluelighter
Joined
Jul 7, 2011
Messages
12,182
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Sitting on a crystal throne in a castle made of LS
So lately Ive been feeling like shit from a lack of serotonin that comes from rolling every weekend for the past like 4-5 months.

Most of the pills lately have been meth/amp, some with MDMA if that matters.

So if I took what I KNOW is a speed bomb in low doses would this affect my serotonin levels? Ive decided to take a nice long break from MDMA for now so I can be happy when Im not high, and I dont want to have to start all over again
 
taking amp is just as, if not more, dangerous than MDMA....you need to take a break from both for at least 4-6 months. Doing any drug on a consistent basis iis harmful and leads to problems down the road.

And to answer your question, though amps dont have as large an effect on seratonin, yes they do affect it.
 
I can't really comment on cross-tolerance, as I'm not experienced with any other amphetamines, but they are not completely different chemicals. MDMA is an amphetamine. That's what the A stands for, even though the effects of MDMA are not really what someone would generally associate with amphetamines.
 
not entirely. LSD and Psylocybin are two completely different substances, but they have cross tolerance. Both amp and MDMA are phenythylamines, so there will be cross tolerance. Additionally, as i mentioned, they both affect seratonin by causing an excess in the receptors.

also, dont get mad if someone tells you something is dangerous. This is a harm reduction site, and any responsible commenter will take a moment to reflect on dangers present in any activity suggested. as i said, the best thing for you to do is stay away from both.

why do you feel the need to keep up with the amp, if i may ask?
 
I feel no need to "keep up with the amp", I just want to get high without going through the depression rolling gives me now. I dont do amphetamines on their own without MDMA usually, and this would most likely be the last time for a long time.

Sorry if it seems like Im getting mad, I appreciate all the info.

and yes it is methylenedioxymethamphetamine, so taking amp would put dampen more the speedy effects than the loving effects it gives right?
 
well, pure MDMA is not that speedy to begin with. If you are talking about cross-tolerance alone (sorry, its a bit unclear what you mean) then yes, but subjectively, since the lovey effects are more present (assuming you are getting pure, which is unlikely even with molly) then both would be dampened.

also, just because MDMA has methamphetamine in the name doesn't mean there is cross tolerance....thatd be like saying drinking water gave you a tolerance to oxygen....or eating salt gave you a tolerance to chorine. It is the fact that they are in the same family of chems, the phens.

Finally, you may have misunderstood...why do you want to keep taking the amp at all? Why not switch it up, drink some weekends, or smoke weed? Fuck, i can get a hella buzz of drinking like 4 cups of coffee.
 
I have a rota usually, when i go out
one weekend it might be k, then same again
then mdma.
then k , More k, mdma And so on.

Get these foods in ya!:

Dark Chocolate (Higher the Cocoa %, The better)
Tuna
Cheese
Turkey
Sour Cherries (Also help you to sleep)
 
rincewindrocks said:
well, pure MDMA is not that speedy to begin with. If you are talking about cross-tolerance alone (sorry, its a bit unclear what you mean) then yes, but subjectively, since the lovey effects are more present (assuming you are getting pure, which is unlikely even with molly) then both would be dampened.

also, just because MDMA has methamphetamine in the name doesn't mean there is cross tolerance....thatd be like saying drinking water gave you a tolerance to oxygen....or eating salt gave you a tolerance to chorine. It is the fact that they are in the same family of chems, the phens.

Finally, you may have misunderstood...why do you want to keep taking the amp at all? Why not switch it up, drink some weekends, or smoke weed? Fuck, i can get a hella buzz of drinking like 4 cups of coffee.
Click to expand...

I smoke weed everyday and I barely get high any more :p did too much acid last time (like a week ago) so Im waiting a bit longer to do that, and really the only other drugs I can get are MDMA and speed. I could get a little tipsy but its like 3pm and Ill feel like shit the rest of the day
 
Wow...
Normally I would post a few chapters on the basics of scientific research....but I just don't have it in me this time.
Besides, you sound like you just want to do it anyways. You aren't really interested in listening to good advice.

You already know the answers, anyways.
You should not be taking MDMA with Amp in it.
If you are talking about ONLY speed, then the cross tolerance is minor.
MDMA does increase dopamine, but speed is 8 times stronger a dopamine releaser.

A little info - MDMA damages serotonin axons, especially in higher thinking/emotional regions of the brain, the prefrontal cortex being the most advanced.
Serotonin serves the primary function of contracting the smooth muscles surrounding your intestines...but in the brain it has a profound effect upon blood distribution.
It is also a modulator of OTHER neurotransmitters!

That means that some of your dopamine pathways are deprived of function because nearby serotonin neurons are NOT working.
The prefrontal cortex is the most sensitive region of the brain to MDMA damage, because it is furthest from the brain stem and the serotonin axons are fiber-like and very thin. It is also the home to your primary reward pathway, known as the meso-limbic reward pathway. It flows from the PFC, your highest emotional/thinking center ALL the way down to the limbic system, where your primal emotions and basic functions are carried out.

By using MDMA, as well as other serotonin drugs like doctor-prescribed SSRIs, you can damage the function of the most advanced part of your brain.
This damages your perception of the world, your personality, and diminishes the perception of pleasure from everyday life.

Alexander Shulgin, the man who gave us MDMA, said that the wait time is 90 days between doses.
Since you didn't follow this guidline to begin with, here is another...

LOTS of research on former MDMA users suggest that recovery from MDMA induced damage takes 12-24 months to recover from.
This does not mean that the PFC is reinnervated - in fact there is plenty of evidence to suggest that dennervation in this region is PERMANENT.
However, 'clinical' recovery occurs over this time frame, meaning the brain compensates in some way allowing the person to feel 'normal' again.

If you cannot wait at least 12 months, you need to ask yourself if you are addicted.
The definition of addiction is continuing to repeat a behavior AFTER real consequences have begun.

LSD can also cause permanent changes in people - I know several. One of them is 50 years old and still sees tracers!
LSD plays with serotonin too, especially in the visual cortex.
You need to lay off ALL serotonin drugs for at LEAST one year.

As far as the amp goes...
It is a dirty fucking drug, no doubt about it.
But as a dopamine agent, not a serotonin agent...the cross-tolerance is not an issue.

HOWEVER, when dopamine activity in the PFC and other cortical regions is compromised, as it is with serotonergic damage, an increase in dopamine will often target the limbic system more than normal. When the balance of dopamine is TOO heavily tilted towards lower brain regions, psychosis is the result.

SOOOO.
Dose VERY carefully. You can always take more LATER, remember that.

Recognize that your dopamine system is NOT functioning normally, and this is one of the reasons you have felt so shitty.
By raising your dopamine levels globally, you may actually feel NORMAL...for a while.

But you ARE at an increased risk for psychosis, especially in higher doses.
You will also feel a harder CRASH when you come off the amp, due to a greater than normal loss of dopamine in cortical regions.
This will encourage you to continue using. BAD IDEA.

Recommendations - exercise daily.
Physical exertion causes a release of Brain Derived Neutrophic Factor in several brain regions, including the cortex.
Not only will this encourage STEM CELLS to generate NEW NEURONS, but it also causes RESPROUTING of serotonin axons.
For real.

Good diet....
And get some Piracetam if you insist on continuing to do pyscheclics and amphetamines.
It increases serotonin and dopamine in the PFC, which will potentiate the effects of the drugs.
It also improves blood flow between the two hemispheres.
It may reduce toxicity as well, but this will NOT offset repeated use.

But for God's sake, give your brain a LONG rest.
Or join the fucking club...
 
Shit.... I know Im not taking a year off of all drugs. I do need to give my brain a rest though. MDMA was my DOC but really im addicted to all drugs. I dont think its too late for my brain though, it was the 3 bombs and 4 hits of acid in a night that really fucked me over for now.

Ecstasy is not the drug it seems... I did decide to stop rolling for a month last week and plan on keeping that if not going longer, like I said I want to see if it would set me back
 
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