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Would 6-HO-DMT be active?

Synaps3

Bluelighter
Joined
Sep 14, 2011
Messages
260
There is 4-HO-DMT (shroom) and 5-HO-DMT (toad), but is there a 6-HO-DMT? Has anyone tried to synthesize it?
 
I can not say for sure, but I think this is a lot more complicated that you are making it seem. Remember that those are abbreviations of a scientific name for a compound. If I am wrong someone correct me...

edit: http://isomerdesign.com/PiHKAL/explore.php?domain=tk&id=5102 Apparently there is, but I doubt you will find any info on it.

edit 2: "6-HO-DMT is a minor metabolite of DMT in man, and it was studied for the same reasons. Could this compound play a role in explaining the activity of the parent dialkylamine? It was explored in a series of subjects who had responded spectacularly to DMT. The five volunteers in this study were former opium addicts who were serving sentences for violation of United States narcotics laws. They were administered 6-HO-DMT at either 0.75 mg/Kg (one subject) or 1.0 mg/Kg (four subjects) and reported no differences from the inactive placebo control. The objective measures (blood pressure, respiration and heart rate, pupillary dilation) confirmed this absence of activity at this level. The active control drug was DMT itself, and it showed the expected responses in all regards."

Quoted from thikal under DET comments
 
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As far as I know 6-fluoro-dmt is not active as a hallucinogen. I don't expect 6-oh would be either

5,6 and 5,7 dihydroxytryptamines are neurotoxic.
 
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