WIN 55,212-2 (racemate, not mesylate salt) question?

[curiosityandcat]

This compound is not the pure R + isomer or the mesylate salt. It is the racemate, containing both the R & S isomers.

There's no effect really when insufflated. I read that its because of it having both of the isomers. Is there any use for this stuff I bought then? Could I take it orally or smoke it? Anyone have any experience with this (non-mesylate)?

 

[dread]

This compound is not the pure R + isomer or the mesylate salt. It is the racemate, containing both the R & S isomers.

Ok, isomers and salt forms are two different things. The compound can be either, R, S, or Racemate, and each of them can be either in freebase or salt form.

If your compound is not in salt form then it's a freebase, which means that it very likely will not be water soluble. Thus it would not work by insufflation.

 

[any major dude]

but you could smoke it...
or eat it, but synthetic cannabinoids are notoriously unreliable when dosed orally. Some people have had decent results with dissolving the powder in oil and putting that in a capsule

 

[mad_scientist]

So you have WIN 55212 freebase then? (pretty sure WIN 55212-2 is the pure (R) isomer, with WIN 55212-1 being the (S) isomer)

Only seen the pure (R) isomer mesylate salt and that is a right bitch to work with, doesn't dissolve in water, can't be smoked and has poor bioavailability by all routes. Still it is active when snorted at 3mg.

If you are sure you have the freebase, perhaps try smoke some, though it will take probably 5mg at least if it is only 50% of the active isomer. Otherwise I guess the best would be to make the tartrate salt and see if you can get the pure (R) isomer that way...

 

[curiosityandcat]

Yeah, I assumed the mesylate (salt form) and the isomer were different, considering people have snorted the mesylate in small dosages of around 3mg and getting a good stoned feeling. So, yes, I have the freebase form, I would like to believe.

How would I go about making the tartrate salt to get the pure (R) isomer? Is it something that if I already don't have the chemistry knowledge to do that I should just not attempt it at all (I'm willing to learn though! :D)?

Thanks again for the replies everyone.

More info

Chemical Name: (5-methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-2-yl)methanone
Synonyms: WIN 55,212-2
Formula: C27H26N2O3
Molecular Mass: 426.51
Purity: 99.46%
Supplied as: Pink/Brown solid
NOTE: This compound is not the pure R + isomer or the mesylate salt. It is the racemate, containing both the R & S isomers.

 

[i<3drugz]

i have had all three, i have had good exp with it orally as the r and racemate not so much the s. great compound. very relaxed not too crazy. i find gelcaps in a watery stomach to be best or up the nose. however more than 6mg nasally can be less than fun and while it causes a good stoning i would rather take it orally at a higher dose ( i have taken up to 40mg orally and though the drop off is still 2 hrs i had a very enjoyable time)