Misc will pretreatment with clonidine avoid/minimize residual effects of ketmine use?

[oxymuffin]

Hi,

After a few articles reading, specially this one

http://www.ncbi.nlm.nih.gov/pubmed/9661567

it made me wondering. Would pre-administration os a low dose of clonidie would, somehow, help ease or eliminate residual effects of prolonged or heavy ketaine use.

Thanks