Will one 8 mg suboxone bring down my oxycodone tolerance?

[aBurningFire]

-oxycodone/heroin every day
-stops use for 24 hours before taking 4 mg of suboxone
-the next morning takes another 4 mg of suboxone
-then waits 72 hours without any opiates whatsoever

in a situation like that, with a 72 hour wait after the last dose of suboxone... would ones oxycodone tolerance be back down to where he could dose with less oxycodone than he normally would and feel it?

 

[K'd-OUT-in-AZ]

No, it will just go back to what it was before you went onto the Suboxone. 72 hours is not going to bring down your tolerance much at all.

 

[aBurningFire]

at least my opiate receptors wont be blocked by the suboxone anymore after waiting 72 hours, right? and thanks for the reply

 

[K'd-OUT-in-AZ]

Yeah, your opiate receptors will no longer be blocked

 

[aBurningFire]

word, thanks

 

[ro0ga]

moderate doses of suboxone over a long period of time will slowly decrease your tolerance to full agonists such as heroin and oxycodone. two days dosing won't do much of anything.

 

[K'd-OUT-in-AZ]

moderate doses of suboxone over a long period of time will slowly decrease your tolerance to full agonists such as heroin and oxycodone. two days dosing won't do much of anything.

Are you sure about that? I don't believe that to be true at all. It doesn't make any sense anyway. Your still taking an opiate daily. I relapsed on my Suboxone to go back on oxycodone for awhile in if anything, my tolerance INCREASED.

 

[ro0ga]

Are you sure about that? I don't believe that to be true at all. It doesn't make any sense anyway. Your still taking an opiate daily. I relapsed on my Suboxone to go back on oxycodone for awhile in if anything, my tolerance INCREASED.

As long as you're not taking huge doses of bupe, it would decrease your tolerance. It's a partial agonist, so it does not exert as much of a euphoric effect compared to full agonist opiates like oxycodone and heroin. It all depends on the dose, you could raise your tolerance if you're taking a larger dose, yes. If you don't allow the suboxone to leave your system, it may seem like it increases your tolerance to other opioids, but that is because it saturates your receptors and prevents other opiates from binding. If you take the minimum amount of suboxone required to hold you so you don't experience withdrawal symptoms, your tolerance will certainly decrease.

The theory behind suboxone being ideal for opiate dependent patients is because by going from a full agonist to a partial agonist, if dosed correctly, will cause your body to begin to downregulate it's opioid receptors and slowly decrease your tolerance (and decrease the amount of opioids required to prevent withdrawal). Don't get me wrong, your tolerance will remain, but not nearly in the same manner as it would if you continued to take full agonists everyday.

The only way suboxone will cause your tolerance to oxycodone to increase is if the dose of suboxone you were taking was higher than what you needed. I've found that most doctors completely go WAY overboard when prescribing suboxone doses...in most cases patients could get away with half the dose of suboxone they were prescribed.