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  • BDD Moderators: Keif’ Richards

Will mixing methadone and lisdexamphamines be fatal?

J

Justamith2

Greenlighter
Joined
Feb 17, 2013
Messages
31
If in the future I take 10mg of methadone and 140mg of lisdexamphetamines, will the l-amps potentate the methadone leading in an overdose(I have only tried opiates a few times, and only 20mg of Vicodin)? I weight 250 pounds, and am experienced with l-amps.
 
No, you'll be fine as long as you are well aquainted with each drug and know that 10mg is a good methadone dose. They only potentiate the euphoria of one another, the CNS effects are actually quite different. Coke plus heroin in one shot was the original speedball, but today, mixing any upper with an opiate is often referred to as 'speedballing' or in this case maybe 'pseudo-speedballing' or 'poor-mans speedballing.'
 
You just gotta be aware that this mixture potentiates positive effects and dulls out the negative effects, often making the user susceptible to inadequately assessing his state of inebriation, and sometimes leading to foolishly re-dosing or adding other chemicals that are potentially dangerous. In the case that you're used to lisdexamphetamine, the methadone should simply take the edge off and make it almost 'too good' of a high. Potential for dependence here is relatively strong.
 
As far as inebriation and adding chemicals to the mix, like he said before "poor mans speedball"(I will also be home at the time it occurs, because I am not one to mix drugs and social scenes). I have no money for anything else, and I know about the dangers of redosing, especially on methadone. As for the addiction, at least with amps, the high for me is perfect and I love it, but what stops me from getting hooked it the comedown. That's why I don't take it often, because the bad feeling and the sleep problems keep me away. I am assuming from my experience with opiates that there is a comedown also, albeit minor. So the mixture of sickness from both of them should snap me out of any mental addictions atleast. As for the physical addiction, I am prepared to go through withdrawals. Because I do not take opiates or amphetamines often, I should not have a large addiction If addiction occurs at all, so I will take a few days off from work/school and nurse it if it happens.
 
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Your methadone dose is low, maintenance drugs are often prescribed with stimulants. I understand you have experience with stimulants but 250 milligrams of lisdexamfetamine is quite high. That's almost equivalent to 110 milligrams of mixed salts amphetamine. Be careful in that respect.

The amphetamine won't potentiate the opioid but they have good synergy when taken orally (poor mans speedball).
 
140 mg of lisdexamphetamines, I weigh 250 pounds (wasn't sure if that played in or not, so I added it). Big difference. I would never take that high a dose, that would be ridiculous for me personally IMO. Also, seeing as I have a low opiate tolerance, and hydrocodone (20mg) worked well last time, u think 10mg will be atleast feel able through the amps.
 
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If it was me, I like taking a low dose amphetamine with my opioid, if you take too much the opioid could go unnoticed.

If 20 milligrams of hydrocodone does you well, then there's no reason 10 milligrams of methadone won't do the same.

140 mg of lisdexamphetamines
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Apologies for the error, I misread your first post. 150 milligrams of lisdexamfetamine is a moderate dose if you have tolerance to amphetamines, but still high for therapeutic purposes.
 
I understand why u would take a low dose of amps so u could feel the opiates, but im kinda trying to get out of script drug use, and want to want to do a "go out with a bang" type deal. Then I want to try coke and MDMA, then slowly recede into psychedelics. In shorts I want to feel the amps too, because I won't be feeling them again.
 
Well getting the balance right for perfect synergy can only be dictated by you, your tolerance to both drugs, your neurochemistry. Start low with the amphetamine and titrate up until you find the suitable dosage.

As for cocaine and MDMA, it's well documented that it's a terrible combination, they both negate the effects of each other, and you will not reap any euphoria from neither drug. As a general rule, drugs of the same class shouldn't be mixed, stimulants and stimulants, dissociatives and dissociatives, benzodiazepines and benzodiazepines etc. There are exceptions ofcourse, but MDMA and cocaine is certainly not one of them.
 
If 20mg of hydrocodone does you good, then you have no business fucking around with methadone...so much more potent...first dose is too unpredictable in terms of the BA unless you snort it, and then that would be WAY to potent...
 
Justamith2 said:
As for the addiction, at least with amps, the high for me is perfect and I love it, but what stops me from getting hooked it the comedown. That's why I don't take it often, because the bad feeling and the sleep problems keep me away. I am assuming from my experience with opiates that there is a comedown also, albeit minor. So the mixture of sickness from both of them should snap me out of any mental addictions atleast.
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Not really, the methadone will probably make the comedown from the lisdexamfetamine easier, I think that's why people were worried it could be easier to develop an addiction - because the side effects and comedown won't be as bad and therefore won't serve as as much of a preventative. So please be careful!
 
Yes, exactly ^

Comedown is made much easier in my experience, thus making the stimulant much easier to use on a more regular basis at higher dosages.
 
Thank you for all of the help. I think I'll just stick to them separately now. Don't want addiction, especially not to opiates, but obviously addiction to amphetamines is in no way good either.
 
You still run risk of addiction taking them separately. Just keep your use infrequent, and try to stay away from methadone. Especially considering your tolerance to it. If you take it a few days in a row, it get stronger and stronger with each use. Then if you drink 12 hours after taking it thinking it had worn off you could easily kill yourself.
 
Thanks for the advice. I usually space out periods of use, and I wasn't planning on making a habit of methadone. I just wanted to understand why people use more potent opiates.
 
Same reason people smoke stronger weed lol. Takes less of the drug, and sometimes higher quality high. ;)
 
The danger with mixing stimulants and opiates is that if your stimulant wears off before your opiate, and your opiate dose is substantially higher than your normal one, you may overdose.

So do not excede your normal dose of methadone and you will be fine. I cannot stress this enough, especially methadone.

Stay safe.
 
Was gonna actually cut it down from 15mg to 10mg just to be on the safe side. (Comes in 15mg)
 
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