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OD Moderators: Keif’ Richards | negrogesic
Opioids will lyrica help with opiate withdrawal?
- Thread starter ohhyaaa
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THECATINTHEHAT
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Random bump.
Just coming off 24mg buprenorphine been taking 300mg pregabalin twice daily and my prescribed lofexidine and the withdrawal has been almost nil so far. Just waking up for day four (really early) and bumped the dosage up to 600mg probably three times a day (due to the short half life) as I approach the point where I essentially have none of the bupe in me (5 half lives). So far I'm completely fine though really.
Surely this drug is going to be licensed and used for opiate withdrawal at some point.
Just coming off 24mg buprenorphine been taking 300mg pregabalin twice daily and my prescribed lofexidine and the withdrawal has been almost nil so far. Just waking up for day four (really early) and bumped the dosage up to 600mg probably three times a day (due to the short half life) as I approach the point where I essentially have none of the bupe in me (5 half lives). So far I'm completely fine though really.
Surely this drug is going to be licensed and used for opiate withdrawal at some point.
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Lorne???
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It depends on your tolerance, but yeah, it certainly helps.
I would like to add that gabapentin itself(which pregabalin, aka lyrica is derived from) also helps opioid withdrawals, mainly because it helps RLS, and high doses can (somewhat) relax you, though of course, lyrica is better.
I would like to add that gabapentin itself(which pregabalin, aka lyrica is derived from) also helps opioid withdrawals, mainly because it helps RLS, and high doses can (somewhat) relax you, though of course, lyrica is better.
jessikkuh_marie
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I have been on a very low dosage of methadone for 2 years. Today I am cutting down from 7.5 to 5mg a day. I took 2.5mg of methadone and .5mg of xanax this morning at the same time. I can feel the effects of the xanax so far. Took both about 45 min ago. I obviously have a tolerance to methadone. But I am new to taking benzos. I was taking 1 or 1.5mg of ativan for a few days before I ran out so I switched to xanax. Is this an Ok combination considering I have a tolerance to methadone but not so much with benzos. I'm kinda paranoid and want to make sure 2.5mg of methadone and .5mg of xanax is ok.
Thanks for your Help.
Thanks for your Help.
blazequietly
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I have been doing the opiate thing for about 7 years now and after some time you really put a lot of effort into finding things to help with withdrawal, although it always ends up just being a bridge to help me along until I can do opiates again I have found some things that work. Some of these things could probably help somebody quit if they really wanted to / needed to. I won't cover all of them, just the ones that pertain to this thread. I'll address Gabapentin (neurontin) and Pregabalin (Lyrica). I have used both and find these two drugs to be the most effective drugs to treat withdrawal. I'm not counting things like suboxone, tramadol, or codeine because that is retarded because they are all opiates (or partial opiates) so you might as well just be doing oxys or hydros and saying that they are helping your withdrawal. Well no shit, thats because they are opiates.
Okay so to get to my point. Lets talk about Gabapentin first. This drug has limited effectiveness when it comes to treating opiate withdrawal. They come in 100, 300, and 400 mg capsules and 600 and 800 mg extended release tablets. In order for Gabapentin to help with withdrawal you need to take high doses. (at least 900 mg, but 1500-3000) for maximum effectiveness. I want to add that for me, for whatever reason the capsules dont work worth a crap. I can take 2-3 grams of capsules and it helps a little bit but Ill still have the runs, the sneezes, the hot flashes. It helps with the appetite a little and helps with the other symptoms I mentioned marginally. The 600 and 800 mg tablets seem to work better for whatever reason. Over all though lets say you are in full blown opiate withdrawal from a decent habit lets go with 80-100mg of oxy a day. You are at a 10 on a scale of 1-10 on the opiate withdrawal scale. The Gabapentin will take you from a 10 to like a 5 on the first day you use them, but tolerance builds fast after a few days gabapentin barely works and might bring you from like a 10 to an 8.
Now lets talk about Lyrica. I fucking love lyrica! it comes in 25, 50, 75, 100, 150, 225 and 300 mg capsule. Lyrica works great for withdrawal. The first 3 days of withdrawal always are the worst IMO and the first is always pretty bad and when the anxiety is the worst because you know all hell is about to break loose. Lyrica has taken me from a 10 on the opiate withdrawal scale to like a -5. I will go from feeling like dog crap to feeling high as a kite. Unfortunately this is only the case for one day for me. I will usually take about 500 mg of lyrica in order to achieve this effect. However, if I take 500 mg for the second day in a row it kind of just makes me sleepy and works on about the same level as gabapentin (well a little better) but youll wanna double your dose each day to get continuous help from the lyrica.
After about 3 or 4 days help from either of the drugs in minimal, but you should be through the worst of your withdrawal anyways (or have found some smack
), if you dont have a huge benzo tolerance you could pick up some xanax, klonopin or valium to help out as they are similar and work on the same (GABA) receptors as the lyrica and gabapentin. With my gigantic benzo tolerance (10mg of xanax doesnt even effect me ) I find benzos to be not helpful at all besides to help sleep during detox.
As others have mentioned it takes about 2 hours for Lyrica to start working (same goes for gabapentin) and lyrica can really fuck you up. I got fired for going to work on lyrica once because I was falling into things and slurring my speech (oopsy daisy). Doses of higher than 800 mg can be excessive and will probably just lead to you passing out for 16+ hours.
Lyrica is the best drug for opiate withdrawal. I am coming to the end of a pretty good H binge right now. Just got up and did a vicodin. I have 20 of the 100 mg lyricas right now so I'm going to take 4 or 5 of them and enjoy my day.
Okay so to get to my point. Lets talk about Gabapentin first. This drug has limited effectiveness when it comes to treating opiate withdrawal. They come in 100, 300, and 400 mg capsules and 600 and 800 mg extended release tablets. In order for Gabapentin to help with withdrawal you need to take high doses. (at least 900 mg, but 1500-3000) for maximum effectiveness. I want to add that for me, for whatever reason the capsules dont work worth a crap. I can take 2-3 grams of capsules and it helps a little bit but Ill still have the runs, the sneezes, the hot flashes. It helps with the appetite a little and helps with the other symptoms I mentioned marginally. The 600 and 800 mg tablets seem to work better for whatever reason. Over all though lets say you are in full blown opiate withdrawal from a decent habit lets go with 80-100mg of oxy a day. You are at a 10 on a scale of 1-10 on the opiate withdrawal scale. The Gabapentin will take you from a 10 to like a 5 on the first day you use them, but tolerance builds fast after a few days gabapentin barely works and might bring you from like a 10 to an 8.
Now lets talk about Lyrica. I fucking love lyrica! it comes in 25, 50, 75, 100, 150, 225 and 300 mg capsule. Lyrica works great for withdrawal. The first 3 days of withdrawal always are the worst IMO and the first is always pretty bad and when the anxiety is the worst because you know all hell is about to break loose. Lyrica has taken me from a 10 on the opiate withdrawal scale to like a -5. I will go from feeling like dog crap to feeling high as a kite. Unfortunately this is only the case for one day for me. I will usually take about 500 mg of lyrica in order to achieve this effect. However, if I take 500 mg for the second day in a row it kind of just makes me sleepy and works on about the same level as gabapentin (well a little better) but youll wanna double your dose each day to get continuous help from the lyrica.
After about 3 or 4 days help from either of the drugs in minimal, but you should be through the worst of your withdrawal anyways (or have found some smack
), if you dont have a huge benzo tolerance you could pick up some xanax, klonopin or valium to help out as they are similar and work on the same (GABA) receptors as the lyrica and gabapentin. With my gigantic benzo tolerance (10mg of xanax doesnt even effect me ) I find benzos to be not helpful at all besides to help sleep during detox.As others have mentioned it takes about 2 hours for Lyrica to start working (same goes for gabapentin) and lyrica can really fuck you up. I got fired for going to work on lyrica once because I was falling into things and slurring my speech (oopsy daisy). Doses of higher than 800 mg can be excessive and will probably just lead to you passing out for 16+ hours.
Lyrica is the best drug for opiate withdrawal. I am coming to the end of a pretty good H binge right now. Just got up and did a vicodin. I have 20 of the 100 mg lyricas right now so I'm going to take 4 or 5 of them and enjoy my day.
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chase_in_56ace
Ex-Bluelighter
Currently about to start day 4 coming off heroin. I'm using the 800mg neurontin tablets which are pretty damn effective if you take a massive dose. I took probably 12g in the first two days and on the third I've only taken 1.6g. You have to titrate doses.. Everything the above poster said was correct.
Check me out though...
70 hrs off ~a gram and a half of very good heroin
Withdrawal level: 2/10 (minor insomnia. Rebound pain but I'm a CPP)
12mg of imodium every 24hrs
25mg Tramadol every 6 hours, sometimes 50mg
4g + neurontin
High grade indica marijuana (very small amounts like 0.3g bowl) as needed
Good food, rest, showers, porn, exercise, repeat.
I honestly feel great. Yes the small dose of imodium helps considerably but the neurontin helps me the most. If I had to choose something on the list to deem essential it's the neurontin. The increase in appetite and water retention is exactly what your body needs during a heavy detox.
Check me out though...
70 hrs off ~a gram and a half of very good heroin
Withdrawal level: 2/10 (minor insomnia. Rebound pain but I'm a CPP)
12mg of imodium every 24hrs
25mg Tramadol every 6 hours, sometimes 50mg
4g + neurontin
High grade indica marijuana (very small amounts like 0.3g bowl) as needed
Good food, rest, showers, porn, exercise, repeat.
I honestly feel great. Yes the small dose of imodium helps considerably but the neurontin helps me the most. If I had to choose something on the list to deem essential it's the neurontin. The increase in appetite and water retention is exactly what your body needs during a heavy detox.
Pregablin actually works very well for opioid withdrawal. It works especially well in dealing with the annoying "neurological" issues that present during withdrawal. The restless legs syndrome, akathisia and general restlessness are mediated greatly by pregabalin in my experience. There seem to be some paradoxical effects with this substance from person to person. Some that I have known experience sedation as a side effect, while with others they experience energy and stimulation (I fall into this cadre). Both of these side effects can be beneficial for on experiencing opioid withdrawal. It might give you some get up and go and get you out of bed, or it might help you relax and sleep; either way it's a win/win.
For me, the overall feelings of inner restlessness are one of the worst symptoms of withdrawal, so pregabalin can be a lifesaver. Note, gabapentin makes a good second choice if you are not able to obtain pregablin (it's a little more tightly controlled where I live). Gabapentin is a reasonable request, especially if you're in withdrawal and MD's aren't overly hesitant to prescribe it, even to those with a documented drug addiction.
For me, the overall feelings of inner restlessness are one of the worst symptoms of withdrawal, so pregabalin can be a lifesaver. Note, gabapentin makes a good second choice if you are not able to obtain pregablin (it's a little more tightly controlled where I live). Gabapentin is a reasonable request, especially if you're in withdrawal and MD's aren't overly hesitant to prescribe it, even to those with a documented drug addiction.
Runtoparadise
Bluelighter
Man, I always bang on about how great lyrica is for withdrawls...was planning on coasting through this week with a box of the 150mgs.
I am prone to blackout on higher doses & just can't afford to do that today, so maybe I just haven't dosed high enough.
I regularly use lyrica as a bridge, maybe once or twice a month for a few days, but not enough to build a tolerance.
So I've come across some codeine for now?
Rtp
I am prone to blackout on higher doses & just can't afford to do that today, so maybe I just haven't dosed high enough.
I regularly use lyrica as a bridge, maybe once or twice a month for a few days, but not enough to build a tolerance.
So I've come across some codeine for now?
Rtp
I am taking about 10 ir 15 methadone right nowi can di a,20 bottke for 3,days then i have to take a larger dose on day 3 like10 to 15 or up to the 20 i am "supposed" to he taking. I have tapered from 90 and have been taking methadone for just over 2 years. The exhaustion is hard but i can take it i can take the diaharrea (i haven't had yet) and headaches with a goody powder ie. Asperin but my arms and my legs i just cabt deal with it i have to move hit punch shake for some kind of rekief but this makes me give in to take at least 10 to 15 of my methadone. I want to cry hecause i want this sooo bad to he free from this monster methadone. I have to plan family vacation around my appointments i am ready to be free help wgat can i do to get relief without this symptom. It is,what is stoppung me from ending this methafone treatment. They have given ne vistaril which is basically glorified b enadryl and lexapro not working for me at all Help me if you can. How long do the muscle probkens go in for
Ds
Bluelight Crew
Lyrica and Neurontin/Gaba will both help with the anxiety and restlessness that come along. Trazadone and(or) Seroquel help when taking in moderation, Traz is good only at night or when your crashing.
Drink plenty of fluids.
Welcome to bl kpme, you should ask a friend or loved one to help with your detox, or if your ballsy do it yourself. Wein yourself off very slowly, not over night. If possible come up with a plan to lower your dose 5-10mg every other day. And take it with plenty of Tagament.
Goodluck
Drink plenty of fluids.
Welcome to bl kpme, you should ask a friend or loved one to help with your detox, or if your ballsy do it yourself. Wein yourself off very slowly, not over night. If possible come up with a plan to lower your dose 5-10mg every other day. And take it with plenty of Tagament.
Goodluck
D's what does tagament do or help? I know fluids to expell abd replenish helps faster detox do you know how kobg the physical muscle symptom last, I am vallsy my hubby says uts not necessary to stop if im not ready but i am i am just the kind of person who GASto know and have ut un my head and then i can deal but if i do t kbow when aprox abd 2 to 6 weeks us too broad i wull go crazy dwelling on it
Potentiates methadone and many other substances by inhibiting enzymes that metabolize them.
mygreenbic
Bluelighter
Lyrics
The only problem with lyrica is your tolerance to it rises so quickly and you may find yourself withdrawal from both your opiate and lyrica.
I think lyrica is the best medicine I've used for opiate withdrawal. It almost completely stopped day three of my Nazi methadone clinic not dosing me at ninety mgs. Other meds that help are baclofen and loperamide or lomotil.
The only problem with lyrica is your tolerance to it rises so quickly and you may find yourself withdrawal from both your opiate and lyrica.
Bliss26
Bluelighter
Is a bundle of H equal to 100mg oxycodone? (20 perks)
I know H has a purity range so no exact conversion, but I was wondering "average" a bundle habit , ?
Is a bundle 10 stamps?
Just wondering. I'm a pharmaceutical user, never used H.
Man in the Dark
Bluelighter
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- Mar 2, 2015
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Lyrica is definitely good for opiate withdrawl I got to day eight using lyrica and benzos, but my pain was just too much to deal with and I had to work. Unfourtanetly I ended back on the pills will be tiring again here shortly.
chase_in_56ace
Ex-Bluelighter
Lyrica will not only help opiate withdrawal; After buprenorphne, Lyrica and gabapentin are literally the two best drugs to combat withdrawal. Their only problems are rapid tolerance build up and a nasty little withdrawal syndrome all of their own thats very mentally taxing. If you're not tolerant to gabaergic chemicals, the first two doses of Lyrica will take ~90% of your symptoms away.
It is that much of a miracle drug.
It is that much of a miracle drug.
mygreenbic
Bluelighter
Oh another thing is lyrica causes some heavy constipation so I imagine this would help the constant bowel movements that accompany severe opiod withdrawal.
Unrelated but lyrica also stops severe amphetamine come downs. If someone can explain the mechanism of why that is we might gain a better understanding on how lyrica can help opiod withdrawal in the sense of neuropharmacology.
Unrelated but lyrica also stops severe amphetamine come downs. If someone can explain the mechanism of why that is we might gain a better understanding on how lyrica can help opiod withdrawal in the sense of neuropharmacology.
Robbiethedoggie
Greenlighter
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- Jul 19, 2016
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Hi everyone! This is my first ever post on here, although I have used it as a point of reference many a time.
Im prescribed Lyrica, 150 mgs twice a day, but I dont take it every day. I use when coming off (have run out!) of the opiates Im also prescribed. Im an extractor as try as I might I cant get stronger painkillers prescribed and Im not sure I fancy H. Too many scary stories for my anxiety to take! It is a wonder drug for withdrawal. I mentioned that I take it to my drug consellor nurse and she said its brilliant as well, so why short term doses arent being given for those wanting off opiates is beyond me.
As mentioned above, tolerance builds very quickly. Id suggest starting at 150-200 and seeing how fucked you get, and then add between 50 each day up until day 5. I would hold off tak8ng more at night because this will just speed up your tolerance. A dose lasts between 9 and 12 hours, so if you can resist for a few hours in the AM, it should see you through until the evening. I find getting some weed makes things a bit more fun with Lyrica and will also help you sleep. Or some OTC sleep meds if you aint a weed smoker.
I find that taking Ibuprofen will assist in aches that aren't diminished by the Lyrica.
Also, Lyrica can help if you are an Alcoholic trying to get sober.
Sorry for rambling.
Im prescribed Lyrica, 150 mgs twice a day, but I dont take it every day. I use when coming off (have run out!) of the opiates Im also prescribed. Im an extractor as try as I might I cant get stronger painkillers prescribed and Im not sure I fancy H. Too many scary stories for my anxiety to take! It is a wonder drug for withdrawal. I mentioned that I take it to my drug consellor nurse and she said its brilliant as well, so why short term doses arent being given for those wanting off opiates is beyond me.
As mentioned above, tolerance builds very quickly. Id suggest starting at 150-200 and seeing how fucked you get, and then add between 50 each day up until day 5. I would hold off tak8ng more at night because this will just speed up your tolerance. A dose lasts between 9 and 12 hours, so if you can resist for a few hours in the AM, it should see you through until the evening. I find getting some weed makes things a bit more fun with Lyrica and will also help you sleep. Or some OTC sleep meds if you aint a weed smoker.
I find that taking Ibuprofen will assist in aches that aren't diminished by the Lyrica.
Also, Lyrica can help if you are an Alcoholic trying to get sober.
Sorry for rambling.
Maddness99
Greenlighter
Lyrica is the best for opiate withdrawal!
I completely agree - today I have had 0 opiates due to the Lyrica I took last night - I was planning on taking suboxone. Lyric is truly a miracle - I am able to function and work like I am fine. The Lyrica did make me sleep like a champ, but I still feel tired. I did not even take my benzos today. I feel foggy and I was afraid to drive this morning. I definitely will take less, I do not want to build a tolerance and go through different withdrawals.
I completely agree - today I have had 0 opiates due to the Lyrica I took last night - I was planning on taking suboxone. Lyric is truly a miracle - I am able to function and work like I am fine. The Lyrica did make me sleep like a champ, but I still feel tired. I did not even take my benzos today. I feel foggy and I was afraid to drive this morning. I definitely will take less, I do not want to build a tolerance and go through different withdrawals.
Man in the Dark
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Lyrica got me off my Year and a half long Morphine and Oxy habit, without much issue. I also used my prescribed k-pins, whih helped a great deal also. I bought a bunch of Kratom also and didn't even need it.