Well I have quite a bit of tolerance to mdma but I'm rolling Saturday and I have waited 3 months so I should be fine. My buddy has some ghb so I was gonna try some tonight. No way do I want to screw up my tolerance right before such a long break so I was wondering if ghb will affect my serotonin or something else that could ruin my break. Thanks
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Will ghb affect my mdma tolerance?
- Thread starter mj1945
- Start date
Folley
Bluelighter
Actually it might have some effect.
GHB is a heavily GABAergic drug, MDMA doesn't effect GABA too much there there is still some overlap there. Also there may be some dopaminergic tolerance, and GHB is one of the only other drugs that releases prolactin (the orgasm hormone) and oxytocin (love hormone) as well so those effects of MDMA would likely be lessened as well. I noticed a bit of a dampening when I was abusing GHB.
it shouldn't be much, and honestly you could probably just ignore it but there should technically be at least a small amount of tolerance there. Certainly more than alcohol, but it shouldn't be extremely pronounced. Using it one time would probably do nothing but if you were using it every day for long periods of time I would expect quite a bit of overlap
GHB is a heavily GABAergic drug, MDMA doesn't effect GABA too much there there is still some overlap there. Also there may be some dopaminergic tolerance, and GHB is one of the only other drugs that releases prolactin (the orgasm hormone) and oxytocin (love hormone) as well so those effects of MDMA would likely be lessened as well. I noticed a bit of a dampening when I was abusing GHB.
it shouldn't be much, and honestly you could probably just ignore it but there should technically be at least a small amount of tolerance there. Certainly more than alcohol, but it shouldn't be extremely pronounced. Using it one time would probably do nothing but if you were using it every day for long periods of time I would expect quite a bit of overlap
