pally pete
Bluelighter
- Joined
- Feb 21, 2010
- Messages
- 2,428
From what I have read over the years, most Opiates require CYP inhibition for potentiation. From what I have learnt, Codeine is the exception to the rule - whereas it needs CYP Induction for potentiation.
How true is this.. as I have a draw full of 100mg Carbamazepine tablets (Which I know is a potent CYP2D6 Inducer) and some CWE Codeine which I've been doing 600mg worth of CWE but not been feeling too much. I know 600mg can be considered wasteful, as there is a disputed ceiling dose of around 300-500mg for Codeine, but I always presume that I lose about 20% through CWE.
Also the solution is never clear, it is a bit cloudy, but when left to stand at room temperature for 10 minutes or so there is no white powder/Paracetamol residue at the bottom of the glass. What I have read is that this is fine to drink, as if there were to be any considerable amount of Paracetamol in the final solution it would sink to the bottom of the glass which I would be able to see.
I have a high tolerance but my Oxy man has let me down, so this is next best thing/only thing.
I've posted on this board before about Codeine and been roasted. Please don't bother replying if your just going to tell me how shit/weak Codeine is.
Thanks in advance
How true is this.. as I have a draw full of 100mg Carbamazepine tablets (Which I know is a potent CYP2D6 Inducer) and some CWE Codeine which I've been doing 600mg worth of CWE but not been feeling too much. I know 600mg can be considered wasteful, as there is a disputed ceiling dose of around 300-500mg for Codeine, but I always presume that I lose about 20% through CWE.
Also the solution is never clear, it is a bit cloudy, but when left to stand at room temperature for 10 minutes or so there is no white powder/Paracetamol residue at the bottom of the glass. What I have read is that this is fine to drink, as if there were to be any considerable amount of Paracetamol in the final solution it would sink to the bottom of the glass which I would be able to see.
I have a high tolerance but my Oxy man has let me down, so this is next best thing/only thing.
I've posted on this board before about Codeine and been roasted. Please don't bother replying if your just going to tell me how shit/weak Codeine is.
Thanks in advance