Why dont long lasting benzos like librium and clonazepam cause rebound anxiety?

[Esperighanto]

Years ago I was taking massive amounts of Xanax … my doctor was actually prescribing them. After a couple years of it I started getting really bad panic attacks and had to move. The new doctor said that I was probably getting panic attacks because I was getting inter dose rebound anxiety because Xanax has such a short half life. So he cut my Xanax dose in half and also prescribed me clonazepam because he said that clonazepam has much longer half life than Xanax and it will smooth out the rebound anxiety. He said to take the clonazepam and only take Xanax as needed. It actually really did work.

*However we all have different back stories and I have severe PTSD (and my ex that was stalking me, found out where I was staying so I had to move again) … anyways so I had a lot going on. The panic attacks were definitely 80-90 % slowed down though when I made that switch to clonazepam. lol hope any of that made sense

I'm glad the benzos helped you in your situation, it's so fascinating to see global perspectives here on BL. I'm an American male from a kind of rough/violent area so the concept of an ex stalking me is a problem solved with lead and some methamphetamine, not benzos, if you catch my drift.

Have you considered to use stacks of benzos? I've found bromornordiazepam's 3.5 day half-life (~a full week of activity from a single dose) to make a fantastic background for carisoprodol, promethazine, tizanidine, hydroxyzine, flualprazolam, bromazolam, phenazolam, alprazolam, GHB (in the form of 1,4-BDO), and etizolam.

 

[AngelsandFairiesarereal]

I'm glad the benzos helped you in your situation, it's so fascinating to see global perspectives here on BL. I'm an American male from a kind of rough/violent area so the concept of an ex stalking me is a problem solved with lead and some methamphetamine, not benzos, if you catch my drift.

I’m from a bad area in the South Bronx and after all the violence I’ve seen (and experienced) I promised myself I’d never kill anyone. My ex tried to murder me but I escaped (barely) … with a broken jaw and multiple, multiple injuries. I wanted to go back and get a gun and go after him for a while but I didn’t want something to go wrong and him another opportunity to hurt me .. he’s like three times the size of me. He had killed before and would have killed me if I didn’t get away. Anyways … my story is actually pretty crazy and long and that’s not even half of it. But years later I’m still glad I never went back and shot him.

Have you considered to use stacks of benzos? I've found bromornordiazepam's 3.5 day half-life (~a full week of activity from a single dose) to make a fantastic background for carisoprodol, promethazine, tizanidine, hydroxyzine, flualprazolam, bromazolam, phenazolam, alprazolam, GHB (in the form of 1,4-BDO), and etizolam.

I always forget I have tons of hydroxyzine lying around until I talk to you on here lol. I also have a bunch of muscle relaxers like cyclobenzaprine and Robaxin. It’s the tramadol, Xanax and clonazepam that I always kind of blow through and then the rest laying around. Maybe I should start utilizing the other meds so I don’t run through the rest so quick. Lol I know you also know about the 7oh excursions Ive been going on

 

[Esperighanto]

I’m from a bad area in the South Bronx and after all the violence I’ve seen (and experienced) I promised myself I’d never kill anyone. My ex tried to murder me but I escaped (barely) … with a broken jaw and multiple, multiple injuries. I wanted to go back and get a gun and go after him for a while but I didn’t want something to go wrong and him another opportunity to hurt me .. he’s like three times the size of me. He had killed before and would have killed me if I didn’t get away. Anyways … my story is actually pretty crazy and long and that’s not even half of it. But years later I’m still glad I never went back and shot him.

Years of peace, healing and meditation has only left me regretting the triggers I didn't pull honestly, but maybe that's just me. As Boldy James said, "Always been a suspect, I could never play the victim". My family has a history of being like that, I suspect I'm just another iteration of those who came before me. The South Bronx is a very different world from Maine, Maine's woods eat whatever we don't want found, the Bronx are very busy and there's not many places to leave material evidence of things, I imagine premeditation is much more intricate and much more of a pain in the ass in NYC than in Maine.

I always forget I have tons of hydroxyzine lying around until I talk to you on here lol. I also have a bunch of muscle relaxers like cyclobenzaprine and Robaxin. It’s the tramadol, Xanax and clonazepam that I always kind of blow through and then the rest laying around. Maybe I should start utilizing the other meds so I don’t run through the rest so quick. Lol I know you also know about the 7oh excursions Ive been going on

How are methocarbomol and cyclobenzaprine? I've yet to try either but muscle relaxants are a beautiful class of drugs imo. I recall you'd mentioned a 7-OH habit recently, I've been rotating between mitragynine, straight kratom leaf, 7-OH, Mitragynine pseudoindoxyl, tizanidine, carisoprodol, promethazine, hydroxyzine and a variety of benzos (flualprazolam, etizolam, and bromonordiazepam predominantly). A lot of focus recently though has been on psychedelic phenethylamines, and they aren't exactly dulled by benzos or muscle relaxants, often they're almost improved by them as far as being "vibe enhancers".

Tonight I'm specifically playing with DOC which is fascinating, but I've got a wicked small amount of it on hand right now and won't be able to grab more for at least a couple months. Considering adding tizanidine, psilacetin, 2C-B, 3-HO-PCP, NEP, DOB, or more DOC to it later, but I've insufflated 1.5mg so far and it's unbelievable how even after a recent large dose (2 nights ago 4mg, half oral half intranasal) this shit feels like super smooth phenethylamine acid. I can't really think of how else to describe the feeling other than "velvet-y" acid, and it's absolutely fascinating, but I want to figure out what else I want to explore mixing it with.

 

[AngelsandFairiesarereal]

Years of peace, healing and meditation has only left me regretting the triggers I didn't pull honestly, but maybe that's just me. As Boldy James said, "Always been a suspect, I could never play the victim". My family has a history of being like that, I suspect I'm just another iteration of those who came before me. The South Bronx is a very different world from Maine, Maine's woods eat whatever we don't want found, the Bronx are very busy and there's not many places to leave material evidence of things, I imagine premeditation is much more intricate and much more of a pain in the ass in NYC than in Maine.

How are methocarbomol and cyclobenzaprine? I've yet to try either but muscle relaxants are a beautiful class of drugs imo. I recall you'd mentioned a 7-OH habit recently, I've been rotating between mitragynine, straight kratom leaf, 7-OH, Mitragynine pseudoindoxyl, tizanidine, carisoprodol, promethazine, hydroxyzine and a variety of benzos (flualprazolam, etizolam, and bromonordiazepam predominantly). A lot of focus recently though has been on psychedelic phenethylamines, and they aren't exactly dulled by benzos or muscle relaxants, often they're almost improved by them as far as being "vibe enhancers".

Tonight I'm specifically playing with DOC which is fascinating, but I've got a wicked small amount of it on hand right now and won't be able to grab more for at least a couple months. Considering adding tizanidine, psilacetin, 2C-B, 3-HO-PCP, NEP, DOB, or more DOC to it later, but I've insufflated 1.5mg so far and it's unbelievable how even after a recent large dose (2 nights ago 4mg, half oral half intranasal) this shit feels like super smooth phenethylamine acid. I can't really think of how else to describe the feeling other than "velvet-y" acid, and it's absolutely fascinating, but I want to figure out what else I want to explore mixing it with.

Maine sounds nice, is the lobster as good as they say lol

Anyways, yea cyclobenzaprine and Robaxin are good … they’re actually pretty different so I would never take them together. My friend did and she was puking her brains out saying she was going to die, she finally recovered the next day. But both are really good with benzos and weed. Cyclobenzaprine makes me drowsy and sedated (I’m pretty sure it’s actually an old tricyclic antidepressant that they started just using as a muscle relaxer). Robaxin is different, you can stay awake on it and also mixes well with tramadol.

Yea 7oh took me on a ride … I was actually using it to replace hydromorphone with … but the 7oh is WAY harder on your body (GI tract, ect.) You’ll definitely withdrawal from that stuff … also the pseudo too. The withdrawals were intense … even with taking tons of tramadol and clonazepam/ Xanax to try to take the edge off … I still was withdrawing and sweating for days trying to get all the 7oh and pseudo out of my system! Im still trying to ride the rest out with regular kratom.

That sounds pretty interesting what you’re taking tonight, I hope you’re enjoying your evening. It’s always nice talking to you

 

[Esperighanto]

Maine sounds nice, is the lobster as good as they say lol

If you're a local it's the cheapest meat you can buy, ~$2/lb. You can also purchase it in cannabis or opioids which is mighty convenient.

It might just be my weird lack of adverse drug effects (never got anxious from a drug, never had a come-down from MDXX's/NBXX's, minimal amphetamine/meth binge hangovers, etc) but I've been able to abuse the fuck out of opioids and never once experience anything even vaguely resembling withdrawal. At this point I'm convinced it might not even be possible for me. In your experience with other drug users, have you ever encountered this before? I haven't, but I'm curious if you or any other BLers have run into similar.

I just added another milligram of DOC intranasally, it's quite interesting, certainly "velvet-y acid". There's something in common between it and 25C-NBOMe for sure, but I've never used 2C-C which I suppose would be the logical intermediate comparison point, so I feel like I have two points of reference without the proper connection point to be able to fully make a comparison/contrast of 25C-NBOMe and DOC, but DOC feels like a smooth stimulating psychedelic, like psychedelic ritalin, and 25C-NBOMe reminds me a lot more of a psychedelic meth that only lasts like 6-8 hours.

Robaxin and Skelaxin are two that I'm interested in trying, as well as Pregabalin and Tolibut. I've used most other muscle relaxants I can access, but those and Cyclobenzaprine have eluded me so far. Carisoprodol is a drug I could take every day for the rest of my life gladly, especially given how much it potentiates serotonergics. Carisoprodol, tianeptine, 2C-B, LSD, 2-FXE, and a super small amount of flualprazolam (~750ug) was one of the best combinations of drugs I've ever used in my entire life. My aversion to sedative compounds will likely lead to favoring Preagabalin, Robaxin and Skelaxin over Cyclobenzaprine, but they'd all still be interesting to try nonetheless. I can eat gabapentin like fucking M&Ms dude, god there's no amount of that shit that I can take without just feeling better and better.

Have you found phenibut, floribut, or tolibut to help you with your opioid WDs? It's always nice talking with you here too, I hope your 7-OH troubles end soon!

 

[SeekingOblivion]

Hey @SeekingOblivian I know that there are Benzodiazepines out there that have significant differences than the 3-4 very common drugs that are prescribed for anxiety and such.

Midazolam (Versed) is very potent and very short-acting. It is most commonly used for anesthesia though I know people who have used them in tablet form. In a hospital, they can give you a continuous flow of the drug through your IV catheter. The short-acting nature of the drug means they can easily knock you out fast and in turn bring you out quickly.

Anyway, I know what I was like when I was young and didn't know anything about the pills I was taking. People saying "oh man, xanny bars hit you harder than anything else bro". Rappers are talking about using Xanax; I can see how people might develop preferences partiall due to true differences in the drugs, but also due to social reinforcement.

In the end, a Benzo addict isn't gonna complain if you're giving him Chlordiazepoxide (Librium) or Alprazolam (Xanax) or Clonazepam (Klonopin). They all work. I guess my obscure point here is that the differences are minute between these drugs, though mental reinforcement/conditioning also play a big role in what someone's preference might be.

I'm not a Benzodiazepine guy though. I would only use them whenever I was doing Amphetamines. They didn't do anything for me outside of helping take the edge off of stimulants.

Opioids are and have always been my thing. I can understand how, when you've done something long enough, you are gonna specialize. For instance, Oxymorphone (Opana; Numorphan) is my favorite of all time. It is a 9/10. Hydromorphone (Dilaudid) is an 8/10 and (Diacetyl)Morphine is a comfortable 7.5/10.

@Esperighanto for future reference 600mg Gabapentin (Neurontin) = 100mg Pregabalin (Lyrica). I feel from experience that this figure is pretty accurate. Of course, once you start going higher in dosage with the former, you start running into a complex pharmacokinetic situation that is too much to describe here.

You’re correct. I found versed, Temazepam and Dalmane, fairly different than the more commonly prescribed ones, for example. You’re also right that in a pinch I would settle for any of them.

 

[AngelsandFairiesarereal]

If you're a local it's the cheapest meat you can buy, ~$2/lb. You can also purchase it in cannabis or opioids which is mighty convenient.

Oh wow that’s pretty cool

It might just be my weird lack of adverse drug effects (never got anxious from a drug, never had a come-down from MDXX's/NBXX's, minimal amphetamine/meth binge hangovers, etc) but I've been able to abuse the fuck out of opioids and never once experience anything even vaguely resembling withdrawal. At this point I'm convinced it might not even be possible for me. In your experience with other drug users, have you ever encountered this before? I haven't, but I'm curious if you or any other BLers have run into similar.

No I never heard of that from another user. Well, actually you know what my grandfather has always taken lots of pain meds for his back and stuff (and on and off stopped them) and I actually asked him if he’s ever felt bad or withdrawal after taking them for a while and stopping and he said no lol.

Robaxin and Skelaxin are two that I'm interested in trying, as well as Pregabalin and Tolibut. I've used most other muscle relaxants I can access, but those and Cyclobenzaprine have eluded me so far. Carisoprodol is a drug I could take every day for the rest of my life gladly, especially given how much it potentiates serotonergics. Carisoprodol, tianeptine, 2C-B, LSD, 2-FXE, and a super small amount of flualprazolam (~750ug) was one of the best combinations of drugs I've ever used in my entire life. My aversion to sedative compounds will likely lead to favoring Preagabalin, Robaxin and Skelaxin over Cyclobenzaprine, but they'd all still be interesting to try nonetheless. I can eat gabapentin like fucking M&Ms dude, god there's no amount of that shit that I can take without just feeling better and better.

Oh yea I remember you talking about carisoprodol in other posts. Also for what it’s worth I think Robaxin is better than skelaxin but maybe your body chemistry is different. Wow now that you mention Gabapentin, I wonder if that could help to take some. My prima that used to send me hydromorphone sent me a couple bottles of gabapentin that I have in my drawers.

Have you found phenibut, floribut, or tolibut to help you with your opioid WDs? It's always nice talking with you here too, I hope your 7-OH troubles end soon!

I never tried any of those actually. Gracias

*Oh btw I wrote like half of this last night and I never actually sent it … lol whoops. So hopefully it’s not too chopped up and all over the place when I send it now

 

[Mr. Krinkle]

i agree with the sentiment that alprozolam / xanax has the worst rebound anxiety because of the short half life

kolonopin barely works for me but my one friend keeps telling me i just need to take more....idk - it did help my back once or twice tho when my back muscles were tightening up on me


i really like these bromazolams - they seem to have a half-life very similar to diazapam which was always my favorite - and i dont get any rebound from it at all

 

[AngelsandFairiesarereal]

i agree with the sentiment that alprozolam / xanax has the worst rebound anxiety because of the short half life

kolonopin barely works for me but my one friend keeps telling me i just need to take more....idk - it did help my back once or twice tho when my back muscles were tightening up on me


i really like these bromazolams - they seem to have a half-life very similar to diazapam which was always my favorite - and i dont get any rebound from it at all

Oh yea for sure clonazepam and Valium are the two benzos that will help me relax muscles in my neck and back.

 

[CavernsoftheMind]

I'm a pretty anxious, neurotic person I'd say.

And yet I've never experienced rebound anxiety.

Not with Alprazolam, Lorazepam, Etizolam, not with the long lasting ones like Diazepam, Clonazepam or Clonazolam.

Never taken them more than twice a week though.

 

[Esperighanto]

No I never heard of that from another user. Well, actually you know what my grandfather has always taken lots of pain meds for his back and stuff (and on and off stopped them) and I actually asked him if he’s ever felt bad or withdrawal after taking them for a while and stopping and he said no lol.

I have a hunch that opioid WDs and MDXX comedowns are psychosomatically exaggerated in people because they hear about how bad they are from people who are generally just weak, and they then internalize that it must somehow be true. Sure there's a slight noticeable opioid WD, but I know tons of people who've never experienced MDXX comedowns even from taking .5-1g a day, daily, for weeks. There was a student org of EDM nerds at my college, it was the only group of people I ever met who routinely purchased MDMA by the ounce, the way ketheads do ketamine.

 

[JackARoe]

I'm a pretty anxious, neurotic person I'd say.

And yet I've never experienced rebound anx. WWhiety.

Not with Alprazolam, Lorazepam, Etizolam, not with the long lasting ones like Diazepam, Clonazepam or Clonazolam.

Never taken them more than twice a week though.

Thanks, that is me but use even less than that. (twice in 2025, funerals lol) I am not anxious too much but have had to use benzo on occasion. I myself get confused at the notion of rebound anxiety. No matter the benzo I still feel sleepy a little the next day. Alprazolam, etizolam, or diazepam I still feel sleepy and calm the next day.

However I suspect that rebound anxiety is a term for people that use a lot more than occasionally. Me personally the quicker a drug can get out my system the better. So occasional short acting benzos seem better for that. I really don't like metabolites running around my system for a week like diazepam. But for someone that uses a lot and experiences rebound anxiety the longer acting the better.

It has been said theoretically on this board that a person that uses diazepam once or twice a week will eventually become dependent after a long time. But that may not be true for shorter acting benzos?