MeDieViL said:
in my opinion taking mdma weekly isnt that bad, altough there are tolerance issues wich i have resolved with piracetam for the time being
saying it turns to a speed like effect is total bullshit, even tough the magic is gone, it still has all the social aspects of it
Well, you obviously just started taking MDMA within the last six months, I'm sure.
I can tell you from experience, that you keep it up...it won't feel simply like "speed".
No way, how could we ever dull down your precious MDMA into considering it to be ANYTHING LIKE AMPHETAMINE? Yeah.
You won't just feel a speedy effect. You'll feel a sloppy ass, dazed feeling. A dazed feeling that feels more simply put, "fucked up". It won't feel like you're rolling, and most likely, YES. It will lose it's serotonergic effect. You expect to combat well-known and accepted abuse to your system with Piracetam? Oh...well, unforunately...
This all goes to show that piracetam produces widely differential effects on the levels and turnover of monoamines in the brain, which are probably very condition-specific. Other studies indicate that piracetam decreases serotonin, dopamine, and norepinephrine brain concentrations in rats, or increases levels of all three [1, 9]. Piracetam yields differential effects on MAO as well, with studies finding either net inhibition or net stimulation [1, 10]. All of this taken together seems to indicate that any effect on monoamines probably occurs far downstream of the original effect, and this would be in line with the observation that no direct effect on dopaminergic, serotonergic, or adrenergic transmission has been found [1].
So, keep using MDMA every week. Take your nootropic too. I mean, the gamble is well worth it, right? Let me put it into a visual for you...
*Wait three months, be quasi-safe from extreme damage and perhaps even maintain the supposed "magic"...
-OR-
*Eat MDMA every week, take a nootropic with no
confirmed direct effect on those receptors, and end up with an extremely harmed serotonin system? (not to mention what else)
If you don't choose the second option and stick to it, you're better off being braindead. Then again, I'd actually question if you were now.
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1. Shorvon S. Pyrrolidone derivatives. Lancet. 2001 Dec 1;358(9296):1885-92