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Who loves DOI?

iblewafuseinmymind

iblewafuseinmymind

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Jul 18, 2008
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This question has bothered me for a long time. I never read a lot about about people's opinions on this strange compound. Visuals are beautiful, but mentally to me it's quite a beast that'll burrow into the mind. Who loves DOI? Who finds it a gem in their book?

January 06 i dropped 2.6mg and it put me in a very strange place. OCD like symptoms, compulsions to do things like a machine. Mine was drawing. I drew a dragon torching a village of stick figures while listening to Old Man's Child's album "In Defiance of Existence" 3 times and battled the impulse of laughing maniacally at the thought of a dragon bursting through a chimney and roaring windows apart, ripping asphalt from dirt, launching cars, and torching inhabitants. So many harsh words went through my mind dealing with destruction and end times. But it was euphoric and maddening.. but not in a favorable and enlightening way. I Listened to the vocalist and pictured that as the voice of the dragon. The motion looped and looped in my mind, the emergence of this dragon being more epic and abrupt. I drew a hideous snake/dragon inhaling a school bus that had needles and knives for teeth. I WOULDN'T be satisfied until the dragon looked as malevolent as possible. Inhaling trees and buildings like its katamari. Plus the drug lasts so damn long and has so many layers to it!

Enough about that though. DOI was a powerful compound that had some of the most unique properties in my book. Very dark indeed. Visuals were very mechanical (green shit shooting out of every angular surface) colors warping distorting in a very unique way. Yeah you'll laugh your ass off but for me laughter was aimed only towards unkind thoughts. They were very cynical and grim. DOI+2CI was even more strange and nothing like anything else. Who enjoys this compound and finds positive insight? Because I find it mania inducing and reminiscent of some machine-like-psychosis. Yet it's intriguing enough to explore again... any thoughts?
 
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First I would say that it was YOUR experience that was dark, not DOI itself that was dark. I've heard of people having positive, wholesome experiences on DOI, so don't try to objectively judge a substance based on a subjective experience. I don't doubt that YOUR experience was geared toward malevolent thinking/imagery, but to say that the substance is such...

That said, I love DOI for an unusual reason. I occasionally take DOI at sub-threshold doses as an anti-inflammatory. I have rheumatoid arthritis, painful inflammation in my large joints, and DOI cuts that out better than ibuprofen. Plus it lasts for the whole day. I don't use it that often though because after a while it is taxing to the mind and emotions. But DOI is great in that it inhibits TNF-alpha mediated inflammation by stimulating the 5HT-2 receptors. Good for arthritis.
 
Very interesting to know. Especially with rheumatoid arthritis running in my family. I agree I suspected the same which is why I began the thread. I want to know what this substance does for other people. Good wholesome critique though. I also have bipolar disorder so perhaps this compound in particular treated me in a rather unkind manner the 5 times I tried it.
 
Me!
DOI is wonderful, especially it's strong visuals on higher doses.
it's only downside for me is the duration by which nobody is able to do it more than twice a year (or so) ...
 
I haven't gotten to try any of the DOx compounds but i greatly want to. I have a feeling that they're very "interesting" - maybe a sort of manic/dark euphoria is how ive always interpretedt he experience would be for me. i look forward to getting my hands on some eventually but its hard to find, and i have so much money slated for other projects - 4-aco-dmt, etc..
 
I've only tried it once, but I thought it was fantastic. It was on blotters, although when I bought the blotters I knew I was buying DOI. They were suppose to be .75 mgs per hit. The first time I tried it I only did 2 and barely even got a +. So the next time I tried it I did 4, so 3 mgs.

I took it while I was tree planting in Northern Ontario. I took it on a party night, and it lasted 24 hours or more. I thought it was very euphoric and sociable. I got to have sex on it which was wonderful. The visuals were very very simple, but they were strong and noticeable. They were actually kind of amusing because the designs it made were so simple.

All in all I found it a very favorable experience. I would definitely do DOI again one day !!
 
From what I have read DOB/DOI seems to have longer duration, more bodyload and unpleasant effects than the more highly rated DOx. Id jump at the opportunity to try either one though, and soon will.
 
Its a fascinating compound for sure. I plan to try it at least once again in my life time. DO compounds share a lot of similarities with their 2C cousins, but they're much more evolved and dynamic. Glad to hear some feedback.
 
I have only experience with DOB (two of them), but I am interested in trying my DOI, DOM, DOC and DOB-dragonfly... but I cannot find the time, furthermore I have not seriously started experimenting again since I stopped for the time being.

My question to you guys though, is why do you think DOB and DOI are mentioned together and then DOC and DOM as well? Can you really pair them like that? (no of course they are all compounds in their own rights but I wonder about the similarities).
DOB was indeed not fun for me, the second experience even turned out a sensory overload after I stupidly ate some hash.

Feeling like a machine really reminds me of it though, I walked through the city I then lived in when it was filled with people on a holiday having a sort of fun fair and I was compelled to analyze how everything worked. To take a distance and think about it, but I felt very little about it.

I have bigger hopes for DOC in this respect and DOM also seems unique to me. Without really knowing all that much about DOI my rather demotivating experiments with DOB and people pairing it with DOB keeps me away from DOI.
 
For me, it was definitely dark in a similar, cynical way like you described. Very intense experience, but not an unpleasent one in the end.
 
DOI was a very neutral experience for me, but I don't have enough experience with it to evaluate its full character.
 
See this looks interesting (infact, all the DOx's do, though DOB makes me a bit nervous) - the molecule is very similar to 2C-I but the duration is 4 or so times greater, with considerably higher potency.

How does this compound compare to 2C-I? Is there much body load?
 
Recent talk about DOI makes me want to finally taste few mgs from my sample...

^ Though molecules look similar, alpha-methylation makes big difference, people report that DOI and 2C-I are quite different subjectively.
 
RhythmSpring said:
That said, I love DOI for an unusual reason. I occasionally take DOI at sub-threshold doses as an anti-inflammatory. I have rheumatoid arthritis, painful inflammation in my large joints, and DOI cuts that out better than ibuprofen. Plus it lasts for the whole day. I don't use it that often though because after a while it is taxing to the mind and emotions. But DOI is great in that it inhibits TNF-alpha mediated inflammation by stimulating the 5HT-2 receptors. Good for arthritis.
Click to expand...

Fascinating. So the test tube research on TNF-alpha inhibition is reproduced in humans then. What kind of dose range did you find produces effective anti-inflammatory action, and are there any noticeable psychedelic effects from such a small amount?
 
After my first DOI dose (3mg-3,5mg) I was like: "Whoa Shulgin must have been drunk the day he devised this molecule!".

As the OP stated, I felt wound up, an uncomfortable amphetamin push behind it all. The visuals were great, but got annoying on day two. Motor control was impaired, walking and moving felt forced, robotical. And there was a slant towards the cynical and sarcastic in the headspace it provided. I don't buy the 'its you not the drug' explanation. If I ever need a trippy chem that would keep me up two or three days on a festival or whatever, I'll maybe give it another go, but until then using it seems pointless in view of so many more agreeable compounds more readily available.

Edit: And yes, 2c-I and DOI are providing distinct experiences apart from differences in potency and duration. 2C-I is a much more pleasant and inviting ride IME, love it actually.
 
agnetha said:
After my first DOI dose (3mg-3,5mg) I was like: "Whoa Shulgin must have been drunk the day he devised this molecule!".

As the OP stated, I felt wound up, an uncomfortable amphetamin push behind it all. The visuals were great, but got annoying on day two. Motor control was impaired, walking and moving felt forced, robotical. And there was a slant towards the cynical and sarcastic in the headspace it provided. I don't buy the 'its you not the drug' explanation. If I ever need a trippy chem that would keep me up two or three days on a festival or whatever, I'll maybe give it another go, but until then using it seems pointless in view of so many more agreeable compounds more readily available.

Edit: And yes, 2c-I and DOI are providing distinct experiences apart from differences in potency and duration. 2C-I is a much more pleasant and inviting ride IME, love it actually.
Click to expand...

Well put. Especially in the higher doses I found it very similar. Actually mixed 1.25mg of DOI and 1.5mg of DOC a few years back. The experience was insane. Quite a disaster. Comprehension was shot. DOI on its own in terms of headspace seems to be similar to a high dose of d-amphetamine+LSD. Quite a push it has on my mind at least.
 
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