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Which antidepressant has worked best for u?

I was perscribed alot of different anit-depressants and none of them worked. They all made me just sit around or sleep. Eventually after doing a bunch of research I asked my doctor to put me on pristiq and it worked instantly . Its been the only one that has worked plus it gives me energy. I love it!
 
lexepro was the first anti-depressant i was put on and it fuelled my drinking and suicidal thoughts to the point that i was put in a mental ward for 3 weeks. mirtazapine is the one AD that actually helped, it also improved cognitive functions a lot and my mood was never higher on it but because of side effects i was taken off it and put on zoloft.

in my experience.. if ssri's do make things better it is around the month and a half mark, up until then it is worse
 
8o
Anon54 said:
Suffer from a little depression/anxiety. thinking of giving ADs a go.
Only really taken Tramadol for a few months for it's SNRI properties. All the others I started, I stopped as soon as a felt any kind of side effects. So I really havn't given them a proper try.

I think benzos a great & all but unfortunetely ya get a tolerance after a while so they arn't really a good long-term solution. fuck havin a massive tollerance to benzos.
8o
I notice most ppl say ADs dont really work well for anxiety & have horrible side-effects, so is there any meds out there for a practical long-term solution for depression/anxiety?

Any comments on any ADs uve tried would be appreciated.
Which would be a good starter AD? (I'm thinking Lexapro or Zoloft)
What's worked best for u?
Click to expand...
Ive been on a list of psych meds from a-z. prozac, ive been on for abour 2.5 yrs. now . This has worked the best for me so far. paxil made me very crazy i had an insane unexplainable desire to do, what exactly i couldnt tell you. it was just bad. effexor withdrawl was long and painful. remeron helps you sleep and it seems to work well.

anti psychotic drugs can cause weight gain and can really screw up your bodies ability to regulate its own blood glucose levels. thioridazine/melaril is a fucking chemical lobotomy. this drug will zombify a large person at a small dose. this is an older class and rarely even perscribed. but its way stronger than thorazine.

lithium caused me acne on my scalp, and depakote maDE my hair fall out. zyprexa gave me 30 extra pounds to carry around.

now im on the prozac and neurontin this combo keeps me level and non suicidal. i also used to mutilate my arms with broken glass as a form of stress relief. not to dwell or anything. whatever im just trying to show you my combo works. i havent cut in 2 yrs. and i never dwell on suicide. occasionally i will have fleeting thoughts of suicide as a solution but never anything serious.

i hope this was able to at least help you in some way.
 
The only anti-depressant I've tried so far is Prozac. Why prescribed it about a month ago for depression and anxiety. I only ended up taking it for a week. It made feel more anxious and disconnected than my depression did. It also made me feel horrible physically. I might try another one in the future but for now I'm just taking st. john's wort and using cannabis regularly.
 
The only anti-depressant to work for me with the least amount of side effects, which i still get quite a bit is Zoloft.

However, it makes me feel detached from the world. Benzo's have worked better for me. Both benzos and anti-depressants are addictive and need tapering to get off them.

I was prescribed zoloft for post alcohol detox depression. It worked but sometimes it made me want to drink more for no reason and the zoloft made me not care about relapsing.

When I tapered off the zoloft because I didn't like the brain zaps and the withdrawal was horrible. Terrible depression (never was diagnosed with depression in the first place) mood swings from sad to suicidally sad, crying for no reason etc.

It works or worked temporarily but I don't like having to deal with the side effects. They are less addictive than benzos when coming to withdrawal but I never took zoloft longer than 3 months.
 
I must be lucky to not have withdrawals from anything... i took adderal and desoxyn for years on end... 11 years for adhd and zoloft prozac etc for years i just stopped takin the shit on and off through out the years in rebellion to my foster parents etc and never had an issue... ever... same with my drug use i can use all i wanna or hardly use at all and it doesnt bother me to stop.... but to answer the Q at hand I think Zoloft was the best of all the A D's i used man... Give it a try it works...
 
Im the OP.
anyways had a choice between lexapro, mirtazepine & Zyprexa.
I went the antipyschotic. Zyprexa I've foud I prefered better than seroquel. I've tried both & the atleast u can control the dose from day to say depending on how dedated u wanna be.
I don't have alot of Valium left & I dont think dr wants to precrive no more.
but these are all short term fixes. Maybe should have got the mirtazepine.
...& theres always all the other crap available without a script. (another story)
I've changed topic here cuz im talking about antipsychotics. but i dont think im gunna keep it uip for long. im a bit... well anxious (can't just sit still & chill out). But im not psychotic. Just an alternative to the otc sleeping stuff i would somtimes take to help me sleep.

what do u rekon Mirtazepine or olanzepine (Zyprexa)?
to help atleast treat insomnia
 
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^Of the two, I'd choose mirtazapine; its less likely to cause akathasia (restlessness) and less likely to bring on a sedated depressive state. That said, mirtazepine can really help with sleep; I know when I was prescribe it, I had to take it at night...
 
Issac Sinclair said:
Tramadol worked for me, but gave me too much sleep. Can you ask your doctor for that?
Click to expand...

I used tramadol for a dew months 150mg which worked OK. I didnt like it or dislike it. if thats the best AD available i dont wanna even bother with em

Rolling stoned mention nicotine.
I just started smoking again & nicotine is a DRI, which another active chemical in tobbaco which is a MAOI. hit cigarettes a dirty. have 1000s of chemicals. & I cant exercise easily. so im gunna quit em again.

but yeah cigarettes effect my mood alot. they are stronger than any otc med used properly. & they are really hard to quit. ive dont it for months.
yet i find it to be more addictive than the valium im taking.. its weird
any drugs i take orally are very weak. cigerattes are strong. weed, i only require a couple of puffs. But with pills (like benzos) i need a handful of the shit to even feel anything. I had ZERO tolerance to opiods & when i was precribed OC they hardly done anything. aprt from the first day when i had Endone (instant release oxy).. 20mg gave me a very mild effect.
 
I was on 50mg. Not right for you then. I never tried another one, I had it for back pain, but I noticed it helped with sociability.
 
Being diagnosed with depression, generalised anxiety disorder and social phobia, after being on prozac, celapram and zoloft, I would have to say that zoloft has had effected me the best. I've been on zoloft for around 6 months now along with a litte seroquel and diazepam.
 
I tried olonzapine for a month or so & found it quit helpfull for sleep with little side efffects at 10mg. at 15mg it gave me a bit of a hangover but it it wasnt so bad
I than tried seroquel which gave me delerium at 250mg. I also felt like i was dreaming but could just wake up. While walking around during waking up half way through the night I found it hard to make my way around my place & felt like i was stumbling. the hangover was worse than zyprexa.

anyways, ive establilsed that zyprexa (olanzapine) is a good anti-pychotic but which helped me sleep but only mildy helped anxiety so nothing bad to say but nothing really good either.

now im onto Mirtazepine. Im starting at 25mg but may move to 50mg. Im concerned about taking a to high dose & it giving me insomnia. & im concerned about the typial kind of restless/stimuldated feeling that can come from ADs.

still interested in what ADs ppl have tried & what they have found most helpful

btw, i recently read an artical saying that Lexapro & Zoloft rated well with helping depression & it then said that Mirtazepine & Effexor also scored well.
 
i have tried SSRIs which basically did nothing to me. i guess bupropion has worked for me but i'm recently starting to suspect by actually making me hypomanic.
 
has anyone found that 50mg of mirtazepine before bed keeps them awake?
or is it more sedating than 25?
im thinking of going from 25 to 50mg...

I want something thats gunna give me lots of motivation/confidence.
maybe effexor?
xanax gave me confidence. & Id imagine so would desoxn. but i dont know how the fuck ppl get prescribed that
 
Sertraline has been fantastic. Its the third SSRI i've tried, the first being Citalopram (didn't enjoy this - weird paranoia feeling in the first few weeks). The second was Fluoxetine - not pleasant - kept looking over my shoulder when walking about - hyped my anxiety up to extreme levels. There seems to be wide-ranging effects in the SSRI drug class (have no experience with Tricyclics, or MAOI's), and the trick is finding the correct one, which is usually achieved via good old trial-and-error.

Sertraline on the other hand is very well tolerated in me. Side effects are few, and I genuinely believe its worked to keep my depression (which is admittedly relatively mild) under a good degree of control. 5-htp doesn't have any effect in enhancing my mood.

I have, however, found Piracetam has strong antidepressant properties in me.

Sertraline withdrawal isn't too great though - weird head buzzing sensations along with enhanced anxiety for 6-8 weeks, came off it for a while a few months back, but had a relapse (stress induced), so am back on the Sertraline, albeit at a lower dose.

Oh yes, Sertraline has wide ranging de-potentiation effects on both Tryptamines and Phenethylamines (though doesn't seem to affect other drugs at all, including Alcohol).
 
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I was on desipramine for a very long time; never had any complaints. I've in fact toyed with the idea of getting back on it, but feel that I'm better off overall on my own.
 
Having suffered from depression since the age of 13(I'm now 21) I've been on numerous antidepressants over the years.
When I was 13 I was prescribed, which I was on for a year before remission.
I stuck to illicit drugs to make me happier from about 14 and a half to the age of 19, by which point I'd developed a bottle of Woods 100(Overproof rum) a night habit.
I was drinking to combat insomnia, so was drinking till I blacked out, then waking up and having the hair of the dog before work.
I'd been to see my GP about insomnia, which I'd experienced since around 15 due to amphetamine and MDMA use, and was prescribed citalopram, which made me feel worse.
I was then moved onto amitriptaline, which I took for a month, then took a 2 month supply overdose.
A few months later I was admitted to a psychiatric unit, where I was treated for depression and alcohol withdrawal. The antidepressant I was prescribed was trazodone, which I took for a year, then discontinued of my own accord.
In November last year I had a psychotic reaction to trying to drink again, wanting to end my life. Back to the GP's.
I was put back on trazodone, but started having episodes similar to a manic phase of bipolar, or temporal lobe epilepsy, so I was admitted back to the psych unit in march this year. I've been moved on to mirtazipine and quetiapine for the time been.
I've had a CT scan and I'm awaiting an EEG to confirm if I'm suffering epilepsy, or I have bipolar, which the literature suggests may be a form of TLE anyway. The drugs used to treat both are one and the same.
Sorry for the life story.
I believe that trazodone was the most affective antidepressant I've ever taken, however, it seems to have activated mania.
However, I think each episode of depression needs assessing, as no one medication seems to work every time.
I wish you all the best, and hope you find something that works.
Stay strong.
 
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