What's The Most Dangerous Drug In The World?

poledriver

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What's The Most Dangerous Drug In The World?

What is the most dangerous drug in the world? This sounds like a relatively simple question: Surely it’s the one most likely to kill you, right? As it turns out, it depends on a multitude of things, from the individual owner's risk to the wider risk to society – and perception plays a large part.

How Do You Define “Dangerous?”

David Nutt is the Edmond J. Safra professor of neuropsychopharmacology at Imperial College London. He’s one of the world’s foremost experts on drugs, in terms of their use, their effects on the human brain, and international drug policy. Drug Science – formally the Independent Scientific Committee on Drugs – is a science-led drugs charity and research organization headed by Professor Nutt.

In 2010, a now-infamous paper was published by the group detailing their scientific analysis on the harms of drugs available in the U.K., both legal and illegal. Sixteen parameters of harm were chosen, and were divided in terms of the specific drug’s direct and individual effects on the user. A direct effect of a drug on a person could be death through an overdose, for example; an indirect effect could be damage caused by becoming infected with HIV while using contaminated syringes. Each drug’s effect on others and the wider society were also taken into account.

The list included mortality likelihood, dependence, impairment of mental functioning, loss of tangible socioeconomic things (such as a house or a job), physical injury, and criminal activities. The economic cost to the country, as well as the international damage (in terms of political and societal destabilization, for example) were also considered.

“Ranking twenty different drugs on sixteen different harms – that’s the best method we’ve had,” Professor Nutt told IFLScience. In a more general sense, the detrimental effects of drugs could be divided into two broad categories: harm to others and harm to users.

Economic vs Personal Harm

his group also had to weight the different criteria – some harms were considered, albeit subjectively, more important than others. “There are two elements to it,” Nutt continued. “Deciding on the various harms – the 16 parameters – most experts agree on that. The more interesting question is how much you care about each of these different rankings; this is where the weightings come in. This could vary greatly depending on the group’s opinions.”

A European group also attempted the same process a few years after the publication of this Lancet study, in collaboration with Drug Science. In terms of the two groups, the British prioritized economic harm more, whereas the Europeans ranked personal harm as considerably more important.

One Every Ten Seconds

With all this taken into consideration, which drugs were considered the most harmful? Mostly due to its harm to others – including the wider economy – alcohol was considered to be by far the most dangerous. Heroin and crack cocaine were next on the list, mostly due to the harm to individual users, although they still had a significant “harm to others” component. Cannabis was ranked 8th for overall harm, whereas ecstasy and LSD were considered among the least harmful. Tobacco was ranked 6th, just behind cocaine.

Despite the European study using different harm weightings, the results were pretty much identical, with an extremely high level of agreement, or correlation, between the two studies. Only a few drugs – methamphetamine and ecstasy – changed positions slightly.

harm%20score.png


“We repeated the study at a European level, expanding it from a smaller British scale – and our experts really agree with each other,” lead author Dr. Jan van Amsterdam, of the Academic Medical Center at the University of Amsterdam, told IFLScience. “We ranked it by personal harm, society harm, and economic harm – but the study was funded by the Ministry of Health, so there was [inevitably] a health focus.”

Regardless, the conclusion seems to be that alcohol is the most dangerous drug around. It directly causes a plethora of diseases, from cardiovascular and neurological disorders to liver degeneration; it indirectly causes transportation accidents, increases promiscuous activities and thus the likelihood of becoming infected by a range of pathogens, and makes an enormous dent in a nation’s economy as it pays for treatment for those suffering from alcohol-related problems.

The World Health Organization (WHO) estimates that 3.3 million deaths every year are caused by the harmful use of alcohol – that’s 5.9 percent of all annual deaths. Shockingly, this is roughly one person every 10 seconds.

Cont -

http://www.iflscience.com/editors-blog/whats-most-dangerous-drug-world-according-science
 
Methamphetamine is one of the most socially corrosive drugs out there IMO. There's no way that drugs like cannabis and ketamine beat it in the "harm to others" quotient...

Anyway, when I think of "dangerous drugs" personally, I usually think of some kind of synthetic opioid or propofol or something
 
It's always the drug that's legal that does the most harm IMO. Just look at booze and cigarettes. I'm living proof. I'm 30 and booze has destroyed me.
 
My vote goes to tobacco. It's the most addictive and the most lethal in the long-term. What more can you ask for? The only downside is the lack of mental intoxication.
 
My vote goes to tobacco. It's the most addictive and the most lethal in the long-term. What more can you ask for? The only downside is the lack of mental intoxication.

Good points, but alcohol causes significant damage in antisocial violent behavior

My vote for most overall destructive drug goes to alcohol, methamphetamine would rank very high for similar reasons.

I wouldn't actually rank opioids all that high. They're very addictive, and can cause a lot of destructive behavior in order to make money for them, but their low physiological destructiveness knocks them off the top spots.
 
Really the only reason alcohol and tobacco are an issue is cause they are legal
 
Really the only reason alcohol and tobacco are an issue is cause they are legal

Probably not true. Alcohol was an even bigger problem when it was illegal in the USA.
 
Thats true, i just meant it's more of a problem cause its everywhere
I need to stop posting when im drunk
 
Only because it's illegal and thus all kinds of... "hobbyists" produce it without any knowledge of chemistry.

Exactly, it's not the desomorphine that necrotizes tissue like that it's the heavy metals and whatever other shitty synthesis byproducts are left in there. The drug itself is no more harmful than other strong opioids, but this is what prohibition leads to, among many other horrors.
 
^^^ Dammit, people beat me to it :( in its street form Desomorphine has to be one of the most dangerous drugs to take, cos of yeah, impurities n shit. Alcohol is socially acceptable to abuse and impairs your judgment to a ridiculous point, as well as being widely available, addictive and used by pretty much everyone. Not surprised it rates the highest.
 
IME, this is me and I'm not speaking in general terms...

Cannabis use causes more problems than cocaine.

After a day's/night's use of cocaine the worst effects that I experience are physical exhaustion, facial swelling/pain and irritability and mood swings the following and second day after use.
Generally all things that my body screams to me "have fun cause we're not doing this for a while after tonight/today", followed the next day by "I'm not doing that again for a while, god why did I do so much etc.".
3-4 days maximum I'm totally back to normal, I don't crave and I've used for a very long time, I am very aware of addiction and the worst thing cocaine does besides the unseen damage to my heart/brain is the impact on my finances. Zero craving after rest.
After resting I have no desire to continue to use as it takes so much out of me, for me it's very much like alcohol. It's nothing I can handle daily or even want.

Weed changes my personality, it changes my eating habits, my sleep patterns, everything.
I am unable to just smoke every once and a while, it becomes daily no matter how much I try, and I have such a hard time trying to resume life after cessation.
Major psychological addiction issues, unable to sleep/cope/live.
I feel the reason it becomes so easy to become a habit is because it is physically benign.

I am not naive to the health damage and toxicity of cocaine, it is much, much harder on the body and toxic than anything cannabis can do, not to mention internal damage that you can't see, but for me cannabis screws my life up more than coke.
 
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I have to agree with the people who said alcohol and tobacco. Tobacco for obvious reasons - it can lead to a very slow and painful death by cancer. And alcohol because it is so easily available.

Clocktower said:
Probably not true. Alcohol was an even bigger problem when it was illegal in the USA.

Disagree to a certain extent. True, we don't have gang violence over alcohol anymore, but cars were not nearly so ubiquitous during Prohibition and what cars were on the road couldn't go very fast. There are numerous times I should have been injured or even killed while driving drunk and escaped harm or with only minor damage to my car (destroyed tires in my case). How many times have we heard about a speeding drunk driver wrapping their vehicle around a utility pole or tree? Or hitting and killing and or injuring others? The easy availability of alcohol now also has an economic impact. I've lost jobs over drinking and there are numerous times where I've just not shown up for work because I was still drunk when I got up, or when I got up I would be way late, so I just didn't bother going. A friend I made in rehab who was a heroin addict said it best, "I feel for you alcoholics. When I need to score, it takes effort. I have to make a bunch of calls and drive to a dealer's house and sometimes it's a long way. Your dealer is 7-Eleven and Publix (grocery store chain)."

I also had a career in higher education before I drank myself out of it, and having worked at what was at the time the Princeton Review's number one party school, I have seen firsthand the effects the easy availability of alcohol has on today's college kids. Along the lines of what my heroin addict friend said, you had to REALLY want alcohol to go to the trouble to get it during Prohibition. Now it's as easy as walking into any convenience store.

Also, look at that bar graph above. Stats don't lie.
 
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I only now noticed one thing. Meth use produces practically no harm to others? What? And regular amphetamine has higher potential to harm others...

Also, what kind of harm to others does the use of cannabis have? And another thing, I think the study is basically somewhat flawed because it assumes the illegality of all the substances except alcohol and nicotine. I don't believe that heroin, crack or meth would harm users more than alcohol or tobacco if they were perfectly legal and regulated (pure, no adulterants, known dosages etc); I mean alcohol is just inevitably toxic - you can't avoid the harm because it and its metabolites are toxic, pretty much same goes for smoking tobacco. Heroin, and I mean pharmaceutical grade diacetylmorphine, is practically harmless if IV isn't your ROA. Most opioids are among the least toxic recreational drugs.
 
My vote goes to tobacco. It's the most addictive and the most lethal in the long-term. What more can you ask for? The only downside is the lack of mental intoxication.

That's pretty much what I have already said about it in the other thread. Besides it's very hard to quit as you smoke basically every hour of the day and there will always be hundreds of triggers that may lead you back to addiction.

Now IMO Crack would be the worst in terms of falling to your rock bottom very fast. Within weeks you can turn to a homeless crack head.

Opiates are also very difficult to stop but I believe you have a lot of tools that can help you to achieve that.
 
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Good points, but alcohol causes significant damage in antisocial violent behavior

My vote for most overall destructive drug goes to alcohol, methamphetamine would rank very high for similar reasons.

I wouldn't actually rank opioids all that high. They're very addictive, and can cause a lot of destructive behavior in order to make money for them, but their low physiological destructiveness knocks them off the top spots.

Yeah and the most likely person to be hurt by a opiate dependent person (that doesn't have a prescription for their supply) is that opiate dependent persons family and statistically speaking the addicts mother.. opiate addiction is unlike any other addiction and usually the person Mom ends up getting sucked into giving their son or daughter money for the drug so they don't get sick or have to steal or what not...
 
The entire family suffers and the opiate dependent who holds all of the guilt.
It's hard to be told to quit something that will make you literally sick, not to mention sad and depressed.
 
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