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Misc What's the best resless leg syndrome drug??

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lfloyd87

lfloyd87

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Apr 22, 2012
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San Francisco, California
I know nothing about it but I have it. Can you guys tell me about it and give me the best drug that I should have in mind at my next p-doc appointment?? I tried searching the forums but I couldn't figure out what my best drug might be to try first. Opinions?? Thanks so much!
 
Is your RLS caused by opioid withdrawal? If so then you will just have to ride it out.
If you're just an RLS sufferer in general then for starters try iron supplements, iron deficiencies are known to cause RLS. If that doesnt work there is a drug called Ropinirole that can help, it's a dopamine agonist and from experience it does help, but it isn't without side effects. Check out the wikipedia page for Ropinirole.
 
Not from opiate withdrawals. So Requip huh? That's the go-to big daddy first-line treatment? I guess I'll mention that I am on 300 mg Wellbutrin daily. Seems like since you guys are talking about dopamine... will this come into play or hinder anything with the Requip? Thanks.
 
Benzos aren't exactly a long term solution tho are they. Ropinirole did help to ease mine, but i stopped taking it because the side effects were nasty. Nausea, temperature fluctuations, and pretty much turned me into a sex pest!
 
My first hunch would be a benzo with good skeletal muscle relaxant properties. Diazepam comes to mind. However, I understand that RLS is actually a neurological disorder so I don't know if a muscle relaxant would be as effective.

I have a bit of experience with with RLS. Mostly through opiate withdrawal, but I've also had bouts of it while trying to lay down and go to sleep after a night of hard drinking. I use marijuana for basically every physical malady in existence, and it seems to work well for RLS. If you take anti-histamines to fall asleep, stop taking them, possibly reduce caffeine and nicotine intake if possible.
 
Benzos are supposed to be good. In fact, the FDA has two benzodiazepines approved for the treatment of RLS, temazepam 7.5 mg (max 15 mg) and clonazepam 0.5 mg (max 1 mg).
 
low dose clonazapam is rx'd for this all the time.

~token

Edit:oops..slow today...i see now kokaino had already beat me to it. :)
 
Oh man, Temazepam would be a sweet deal for RLS relief. That's basically one of the most enjoyable drugs ever, I can't believe some people get Temazies where others get crappy Mirapex or Requip 8)
 
Benzos aren't very good for RLS, they don't really do shit besides help you fall asleep (seriously read the articles on it, its better for PLMS which is common for individuals with RLS). Something like Gabapentin, pramipexole, ropinirole, tramadol, propoxyphene, methadone, etc. are all good RLS medications.

I currently take methadone 30mg/day and 2mg of clonazepam before bed for severe RLS and PLMS.

Most doctors will start you on pramipexole (dopamine agonists) as a first line treatment, then move on to benzos (though some will start with benzos, but with newer info out, it isn't as common to start with), then try gabaergics like gabapentin, and possibly low potency opioids. You wont start getting into potent opioids unless all the other options haven't helped.

I would type more on this subject, or pull of the couple of post that I have made on the subject here, but here is a good site in the mean time, ignore the simple design.

http://www.rlshelp.org/ <-- one of the best resources for starting to understand RLS. Theres letters from patients, treatment options (drug and non-drug related), links to other sites, etc.
 
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We aren't here to assist you with obtaining specific medications, scheduled or not, from doctors.

This type of discussion is better saved for when you're in the doctors office, with the doctor. They have your medical records and can evaluate you in person, we know nothing of your medical background and the majority of us are not qualified to assess you even if we had your chart in front of us.
 
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