Tianeptine (12.5 mg 3x daily for 2 weeks, noticed a slight increase in mood/motivation)
I had wonderful results with Tianeptine Sodium, but I was taking 30-40mg BID.
What country do you live in? I was speaking with a fellow BL'er who told me they have begun, with positive results, Valdoxan (agomelatine). This person lives in Australia, though it is prescribed in the EU, too. In 2011 there were plans for Novartis Pharma to begin marketing the drug, but Im not sure what happened to it as it is 2013 and still not FDA approved, no marketed at all in the US.
It's mechanism of action is really rather interesting! Here is the Pharmacodynamics section of the Wikipedia article on agomelatine:
Of all the meds mentioned these two are definitely some of the more unusual brands. Like yourself op I tried tianeptine got an initial buzz from it which faded fast then gave up on it in a very similiar time scale to your own but I have heard that if you stick with it ie 2-3 months then the effects of it can be very good. Many people make the mistake of trying it getting an instant fix then thinking it has stopped working once the buzz wears off. I made this mistake also so something to bare in mind. Of your list I havent tried them all but been through quite a few one of the most effective for me (ie I felt something) was effexor but it made me feel totally out of my mind and I couldnt imagine being able to function normally on it. After about 3 months I gave up.
Re Valdoxan ive actually axed what the psych is telling me and made the decision to purchase this stuff myself. I too feel there is some very unusual qualities about this drug and I plan to try it soon. Other than that I feel with all of this AD medication there always seems to be something missing. It never seems to work properly. I hate to sound like a conspiracy theory developer but judging by the money the likes of Effexor make selling this junk I cant see there being a massive motive to actually develop something that works. Maybe one day there will be a pill that fixes us
