what kind of questions are you asking? What are you opening up with?
It really just varies between members... I'll usually try to come up with something to ask them about their profile like a band they like or such. If they don't list much on their profile for me to work with I'll usually just say hi and tell them I would like to know more about them.
Here's a few examples...
Me: Hi there... Ok I just have to ask, what the heck is environmental services at a hospital? lol
Her: Housekeeping
Me: Ah ok, I used to do that for a bed and breakfast. How are you?
Her: No reply
Another...
I ask a member who I was talking to what she was up to. She says getting ready to go out of town with her kids. I ask her where she's going. She takes it like I'm going to fucking stalk her or something and blocks me. lol
As far as people I haven't heard back from...
Me to someone who was putting down their looks on their profile: Hey how are you? Was looking at your profile, you shouldn't say you're not as pretty as most, you have some nice features.
Me to someone who claimed they had never been on a date before (although I think they were lying): Hmmm so you've never been asked out on a date... So wanna go on a date? lol Would like to know more about you.
Me: Hey there... I read your profile, sounds like have some things in common. Would like to chat some if you're interested.
Me: Hey how are you doin? That's a cool shirt where did you get it?
Me on someone's bands that they like: Props on the Pantera and Hank... Have you ever listened to Hank III?
Me: Hey how's it going? What do you think about asparagus?
Me: responding to someone who was actually topless in their photos lol: Wow you're not shy about your body. Very nice.
That's probably enough examples.